{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T23:19:29Z","timestamp":1791674369355,"version":"4.3.4"},"reference-count":25,"publisher":"Massachusetts Medical Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2025,7,31]]},"DOI":"10.1056\/nejmoa2502114","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T21:00:16Z","timestamp":1753909216000},"page":"469-478","source":"Crossref","is-referenced-by-count":16,"title":["Resolution of Squamous-Cell Carcinoma by Restoring T-Cell Receptor Signaling"],"prefix":"10.1056","volume":"393","author":[{"given":"Peiying","family":"Ye","sequence":"first","affiliation":[{"name":"Laboratory of Immunoregulation and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna R.E.","family":"Bergerson","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Brownell","sequence":"additional","affiliation":[{"name":"Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel J.","family":"Starrett","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular Oncology, National Cancer Institute (NCI), Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshini S.","family":"Abraham","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Nationwide Children\u2019s Hospital, Columbus, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan V.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Laboratory of Immunoregulation and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Triscia","family":"Martin","sequence":"additional","affiliation":[{"name":"Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek","family":"MacMath","sequence":"additional","affiliation":[{"name":"Laboratory of Immunoregulation and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Sun","family":"Kuehn","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyothi","family":"Padiadpu","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung, and Blood Institute, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Immune Regulation Unit, National Institute of Dental and Craniofacial Research, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio D.","family":"Rosenzweig","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxane","family":"Tussiwand","sequence":"additional","affiliation":[{"name":"Immune Regulation Unit, National Institute of Dental and Craniofacial Research, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren J.","family":"Leonard","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung, and Blood Institute, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Pittaluga","sequence":"additional","affiliation":[{"name":"Department of Pathology, NCI, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Raffeld","sequence":"additional","affiliation":[{"name":"Department of Pathology, NCI, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle E.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Immune Deficiency Cellular Therapy Program, NCI, NIH, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1475-356X","authenticated-orcid":false,"given":"Andrea","family":"Lisco","sequence":"additional","affiliation":[{"name":"Laboratory of Immunoregulation and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2206348"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.1187"},{"key":"e_1_3_5_4_2","unstructured":"American Cancer Society. Cancer facts and figures 2024 (https:\/\/www.cancer.org\/research\/cancer-facts-statistics\/all-cancer-facts-figures\/2024-cancer-facts-figures.html)."},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.11.037"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15967"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pvr.2019.04.003"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(23)00459-X"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2102715"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiab025"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI180251"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-020-02183-x"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00576"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2020.01.035"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27581"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.4530"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41525-021-00226-4"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06027-1"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1015"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40822-9"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018016113"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a002279"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2020.2327"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2015.02.004"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1719-9"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2024.11.013"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2502114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T21:00:36Z","timestamp":1753909236000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2502114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,7,31]]}},"alternative-id":["10.1056\/NEJMoa2502114"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2502114","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]}}}