{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:13:53Z","timestamp":1792844033865,"version":"4.5.0"},"reference-count":35,"publisher":"Massachusetts Medical Society","issue":"7","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"funder":[{"DOI":"10.13039\/501100013120","name":"EMA","doi-asserted-by":"publisher","award":["EMA\/2021\/17\/TDA"],"award-info":[{"award-number":["EMA\/2021\/17\/TDA"]}],"id":[{"id":"10.13039\/501100013120","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003042","name":"Else Kr\u00f6ner-Fresenius-Stiftung","doi-asserted-by":"publisher","award":["Dr. Schonburg"],"award-info":[{"award-number":["Dr. Schonburg"]}],"id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Universitatsmedizin Greifswald","award":["Gerhard Domagk Research Program(Schonborn, Muller)"],"award-info":[{"award-number":["Gerhard Domagk Research Program(Schonborn, Muller)"]}]},{"name":"Next Generation Sequencing Competence Network","award":["Project 407495230 (DFG Research Infrastructure NGS"],"award-info":[{"award-number":["Project 407495230 (DFG Research Infrastructure NGS"]}]},{"name":"Next Generation Sequencing Competence Network","award":["Project 423957469"],"award-info":[{"award-number":["Project 423957469"]}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["374031971-TRR240"],"award-info":[{"award-number":["374031971-TRR240"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["GR 2232\/9-1"],"award-info":[{"award-number":["GR 2232\/9-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SCHO 2052\/1-1"],"award-info":[{"award-number":["SCHO 2052\/1-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["TH 2320\/3-1"],"award-info":[{"award-number":["TH 2320\/3-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2037700"],"award-info":[{"award-number":["2037700"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001422","name":"ASH Foundation","doi-asserted-by":"publisher","award":["ASH Global Research Award-Dr. Schonborn"],"award-info":[{"award-number":["ASH Global Research Award-Dr. Schonborn"]}],"id":[{"id":"10.13039\/100001422","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022217","name":"Flinders Foundation","doi-asserted-by":"publisher","award":["Health Seed Grant (Dr. Wang)"],"award-info":[{"award-number":["Health Seed Grant (Dr. Wang)"]}],"id":[{"id":"10.13039\/501100022217","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2026,2,12]]},"DOI":"10.1056\/nejmoa2514824","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T22:00:26Z","timestamp":1770847226000},"page":"669-683","source":"Crossref","is-referenced-by-count":26,"title":["Adenoviral Inciting Antigen and Somatic Hypermutation in VITT"],"prefix":"10.1056","volume":"394","author":[{"given":"Jing Jing","family":"Wang","sequence":"first","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"},{"name":"Department of Immunology, South Australia Pathology, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6660-9949","authenticated-orcid":false,"given":"Linda","family":"Sch\u00f6nborn","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8046-7588","authenticated-orcid":false,"given":"Theodore E.","family":"Warkentin","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7942-3273","authenticated-orcid":false,"given":"Luisa","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0177-6508","authenticated-orcid":false,"given":"Thomas","family":"Thiele","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Ulm","sequence":"additional","affiliation":[{"name":"Friedrich Loeffler Institute of Medical Microbiology, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"V\u00f6lker","sequence":"additional","affiliation":[{"name":"Department of Functional Genomics, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3095-8362","authenticated-orcid":false,"given":"Sabine","family":"Ameling","sequence":"additional","affiliation":[{"name":"Department of Functional Genomics, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f6ren","family":"Franzenburg","sequence":"additional","affiliation":[{"name":"Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Kaderali","sequence":"additional","affiliation":[{"name":"Institute of Bioinformatics, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Tzvetkova","sequence":"additional","affiliation":[{"name":"Institute of Bioinformatics, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Colella","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Chataway","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee Wee","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridie","family":"Armour","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Troelnikov","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Rutten","sequence":"additional","affiliation":[{"name":"Johnson & Johnson Innovative Medicine, Leiden, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"McCluskey","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Zahn","sequence":"additional","affiliation":[{"name":"Johnson & Johnson Innovative Medicine, Leiden, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom P.","family":"Gordon","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia"},{"name":"Department of Immunology, South Australia Pathology, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8343-7336","authenticated-orcid":false,"given":"Andreas","family":"Greinacher","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Universit\u00e4tsmedizin Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2104882"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2104840"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2105385"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2024.01.045"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.280154"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2307721"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023022136"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2310644"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2402592"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022016474"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2021014588"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023021307"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines13010003"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/v13030388"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(99)00003-4"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2012.01118.x"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2023.06.027"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107051"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2112974"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-05-850370"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-11-3994"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.7.4311"},{"key":"e_1_3_5_24_2","first-page":"102925","article-title":"A mouse model of vaccine-induced immune thrombocytopenia and thrombosis (VITT).","volume":"9","author":"M\u00fcller L","year":"2025","unstructured":"M\u00fcller L, Klauke J, Owczarek C, et al. A mouse model of vaccine-induced immune thrombocytopenia and thrombosis (VITT). Res Pract Thromb Haemost 2025;9:Suppl 2:102925-102925.","journal-title":"Res Pract Thromb Haemost"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.214"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2021012217"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03744-4"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1913810117"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/v16111747"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2507175"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR02132D"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14945"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.20092"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000661"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16275"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.19354"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2514824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T22:00:36Z","timestamp":1770847236000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2514824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,12]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,2,12]]}},"alternative-id":["10.1056\/NEJMoa2514824"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2514824","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,12]]}}}