{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T21:35:38Z","timestamp":1794000938918,"version":"4.8.0"},"reference-count":18,"publisher":"Massachusetts Medical Society","issue":"18","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"funder":[{"DOI":"10.13039\/501100000664","name":"Health Technology Assessment Programme","doi-asserted-by":"publisher","award":["NIHR130593"],"award-info":[{"award-number":["NIHR130593"]}],"id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2026,5,7]]},"DOI":"10.1056\/nejmoa2515704","type":"journal-article","created":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T13:32:31Z","timestamp":1774791151000},"page":"1779-1789","source":"Crossref","is-referenced-by-count":44,"title":["Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention"],"prefix":"10.1056","volume":"394","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6362-1291","authenticated-orcid":false,"given":"Divaka","family":"Perera","sequence":"first","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8256-195X","authenticated-orcid":false,"given":"Matthew","family":"Ryan","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad M.","family":"Ezad","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"University Hospitals Dorset NHS Foundation Trust, Bournemouth, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohail Q.","family":"Khan","sequence":"additional","affiliation":[{"name":"University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Webb","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"King\u2019s College Hospital NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"O\u2019Kane","sequence":"additional","affiliation":[{"name":"University Hospitals Dorset NHS Foundation Trust, Bournemouth, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan","family":"Weerackody","sequence":"additional","affiliation":[{"name":"Bart\u2019s Health NHS Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Dodd","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Kwok","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Laidlaw","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Van Dyck","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Wrigley","sequence":"additional","affiliation":[{"name":"Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian W.","family":"Strange","sequence":"additional","affiliation":[{"name":"University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Bagnall","sequence":"additional","affiliation":[{"name":"Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzin","family":"Fath-Ordoubadi","sequence":"additional","affiliation":[{"name":"Manchester University NHS Foundation Trust, Manchester, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios F.","family":"Panoulas","sequence":"additional","affiliation":[{"name":"Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Ladwiniec","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester NHS Trust, Leicester, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Davies","sequence":"additional","affiliation":[{"name":"Mid and South Essex NHS Foundation Trust, Basildon, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Chase","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colum G.","family":"Owens","sequence":"additional","affiliation":[{"name":"Belfast Health and Social Care Trust, Belfast, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Watkins","sequence":"additional","affiliation":[{"name":"NHS Golden Jubilee, Glasgow, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haseeb","family":"Rahman","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilesh","family":"Pareek","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, King\u2019s College London, London"},{"name":"King\u2019s College Hospital NHS Foundation Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnaraj","family":"Rathod","sequence":"additional","affiliation":[{"name":"Bart\u2019s Health NHS Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Rawlins","sequence":"additional","affiliation":[{"name":"University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Evans","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen P.","family":"Hoole","sequence":"additional","affiliation":[{"name":"Royal Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod H.","family":"Stables","sequence":"additional","affiliation":[{"name":"Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Curzen","sequence":"additional","affiliation":[{"name":"University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Clayton","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu303"},{"issue":"3","key":"e_1_3_4_3_2","first-page":"e18","article-title":"2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines.","volume":"145","author":"Lawton JS","year":"2022","unstructured":"Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines. Circulation 2022;145(3):e18-e114.34882435","journal-title":"Circulation"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1190"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2008.11.005"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.124.011636"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2025.09.008"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2022.08.032"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.098194"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.044007"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.123.013367"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.09.015"},{"key":"e_1_3_4_13_2","first-page":"219","article-title":"The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease.","volume":"1","author":"Sianos G","year":"2005","unstructured":"Sianos G, Morel M-A, Kappetein AP, et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 2005;1:219-227.19758907","journal-title":"EuroIntervention"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2024.04.043"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr352"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-308562"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2022.02.006"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.17925\/HI.2020.14.2.92"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2312572"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2515704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T21:00:32Z","timestamp":1778101232000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2515704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":18,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,5,7]]}},"alternative-id":["10.1056\/NEJMoa2515704"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2515704","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]}}}