{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:50:58Z","timestamp":1792572658909,"version":"4.5.0"},"reference-count":92,"publisher":"Massachusetts Medical Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2008,3,6]]},"DOI":"10.1056\/nejmra072753","type":"journal-article","created":{"date-parts":[[2008,3,5]],"date-time":"2008-03-05T17:31:31Z","timestamp":1204738291000},"page":"1037-1052","source":"Crossref","is-referenced-by-count":723,"title":["Acute Pulmonary Embolism"],"prefix":"10.1056","volume":"358","author":[{"given":"Victor F.","family":"Tapson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01795.x"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032274"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.6.458"},{"key":"r004","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/014107688908200407","volume":"82","author":"Sandler DA","year":"1989","journal-title":"J R Soc Med"},{"key":"r005","doi-asserted-by":"crossref","first-page":"163S","DOI":"10.1378\/chest.101.4_Supplement.163S","volume":"101","author":"Elliott CG","year":"1992","journal-title":"Chest"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2004.01094.x"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.6.585"},{"key":"r008","doi-asserted-by":"crossref","first-page":"267a","DOI":"10.1182\/blood.V106.11.267.267","volume":"106","year":"2005","journal-title":"Blood"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800720211"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp067264"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00039403"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1002575"},{"key":"r013","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1182\/blood.V86.10.3685.bloodjournal86103685","volume":"86","author":"Ginsberg JS","year":"1995","journal-title":"Blood"},{"key":"r014","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1182\/blood.V85.6.1504.bloodjournal8561504","volume":"85","author":"Rosendaal FR","year":"1995","journal-title":"Blood"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.5.3372"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1378\/chest.100.3.598"},{"key":"r019","doi-asserted-by":"crossref","first-page":"589","DOI":"10.7326\/0003-4819-140-8-200404200-00005","volume":"140","author":"Stein PD","year":"2004","journal-title":"Ann Intern Med"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2007.02328.x"},{"key":"r021","doi-asserted-by":"crossref","first-page":"98","DOI":"10.7326\/0003-4819-135-2-200107170-00010","volume":"135","author":"Wells PS","year":"2001","journal-title":"Ann Intern Med"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.2.172"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.1.92"},{"key":"r024","doi-asserted-by":"crossref","first-page":"165","DOI":"10.7326\/0003-4819-144-3-200602070-00004","volume":"144","author":"Le Gal G","year":"2006","journal-title":"Ann Intern Med"},{"key":"r025","doi-asserted-by":"crossref","first-page":"812","DOI":"10.7326\/0003-4819-144-11-200606060-00007","volume":"144","author":"Kearon C","year":"2006","journal-title":"Ann Intern Med"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.22.2483"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01709.x"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.6.1947"},{"key":"r029","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.5858\/2006-130-1326-CODAAP","volume":"130","author":"Melanson SE","year":"2006","journal-title":"Arch Pathol Lab Med"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2222001802"},{"key":"r031","doi-asserted-by":"crossref","first-page":"866","DOI":"10.7326\/0003-4819-141-11-200412070-00011","volume":"141","author":"Moores LK","year":"2004","journal-title":"Ann Intern Med"},{"key":"r032","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1148\/radiology.219.2.r01ma26498","volume":"219","author":"Loud PA","year":"2001","journal-title":"Radiology"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052367"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1001\/jama.263.20.2753"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.156.5.531"},{"key":"r036","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1164\/ajrccm.160.3.16030","volume":"160","author":"Tapson VF","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.0756"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90274-K"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1378\/chest.105.3.888"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3_suppl.401S"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2000.110352"},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341101"},{"key":"r043","doi-asserted-by":"crossref","first-page":"789","DOI":"10.7326\/0003-4819-130-10-199905180-00002","volume":"130","author":"Gould MK","year":"1999","journal-title":"Ann Intern Med"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.157.22.2562"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01819.x"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1546"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7933.2004.00647.x"},{"key":"r048","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199709043371002"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199709043371001"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035451"},{"key":"r051","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.2.229"},{"key":"r052","doi-asserted-by":"crossref","first-page":"191","DOI":"10.7326\/0003-4819-134-3-200102060-00009","volume":"134","author":"Merli G","year":"2001","journal-title":"Ann Intern Med"},{"key":"r053","doi-asserted-by":"crossref","first-page":"867","DOI":"10.7326\/0003-4819-140-11-200406010-00007","volume":"140","author":"Buller HR","year":"2004","journal-title":"Ann Intern Med"},{"key":"r054","doi-asserted-by":"crossref","first-page":"211","DOI":"10.7326\/0003-4819-146-3-200702060-00150","volume":"146","author":"Segal JB","year":"2007","journal-title":"Ann Intern Med"},{"key":"r055","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3_suppl.188S"},{"key":"r056","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39098.583356.55"},{"key":"r057","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054444"},{"key":"r058","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025313"},{"key":"r060","doi-asserted-by":"publisher","DOI":"10.1038\/nature00963"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802123380701"},{"key":"r062","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-0631"},{"key":"r063","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000203418-39769.0D"},{"key":"r064","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(67)90104-X"},{"key":"r065","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.3.877"},{"key":"r066","doi-asserted-by":"publisher","DOI":"10.1378\/chest.111.1.218"},{"key":"r067","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.154.14.1601"},{"key":"r068","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.19.2197"},{"key":"r069","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021274"},{"key":"r070","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)07534-5"},{"key":"r071","doi-asserted-by":"publisher","DOI":"10.1378\/chest.106.5.1558"},{"key":"r072","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2004.10.023"},{"key":"r073","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90792-O"},{"key":"r074","doi-asserted-by":"publisher","DOI":"10.1001\/jama.236.13.1477"},{"key":"r075","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3_suppl.338S"},{"key":"r076","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.17.1909"},{"key":"r077","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.09.057"},{"key":"r078","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2993"},{"key":"r079","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60202-0"},{"key":"r080","first-page":"101","volume":"25","author":"Nicolaides AN","year":"2006","journal-title":"Int Angiol"},{"key":"r081","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2106\/00004623-199401000-00002","volume":"76","author":"Colwell CW","year":"1994","journal-title":"J Bone Joint Surg Am"},{"key":"r082","doi-asserted-by":"publisher","DOI":"10.1054\/arth.2001.21499"},{"key":"r083","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199609053351003"},{"key":"r084","doi-asserted-by":"crossref","first-page":"571","DOI":"10.7326\/0003-4819-113-8-571","volume":"113","author":"Green D","year":"1990","journal-title":"Ann Intern Med"},{"key":"r085","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909093411103"},{"key":"r086","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000138928.83266.24"},{"key":"r087","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38733.466748.7C"},{"key":"r088","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2003.189"},{"key":"r089","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60633-3"},{"key":"r090","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00373-5"},{"key":"r091","unstructured":"Hull RD, Schellong S, Tapson V, et al. Extended-duration venous thromboembolism prophylaxis in acutely ill medical patients with recent reduced mobility: the EXCLAIM study. In: Program and abstracts of the XXI Congress of the International Society on Thrombosis and Haemostasis, Geneva, July 6\u201312, 2007:O-S-001."},{"key":"r092","first-page":"641","volume":"180","author":"Rogers FB","year":"1995","journal-title":"J Am Coll Surg"},{"key":"r096","doi-asserted-by":"crossref","first-page":"697","DOI":"10.7326\/0003-4819-143-10-200511150-00006","volume":"143","author":"Heit JA","year":"2005","journal-title":"Ann Intern Med"},{"key":"r097","doi-asserted-by":"publisher","DOI":"10.1161\/hq0202.102318"},{"key":"r098","doi-asserted-by":"crossref","first-page":"689","DOI":"10.7326\/0003-4819-132-9-200005020-00002","volume":"132","author":"Grady D","year":"2000","journal-title":"Ann Intern Med"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMra072753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T04:39:23Z","timestamp":1630816763000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMra072753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,6]]},"references-count":92,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,3,6]]}},"alternative-id":["10.1056\/NEJMra072753"],"URL":"https:\/\/doi.org\/10.1056\/nejmra072753","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,6]]}}}