{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:53:49Z","timestamp":1791417229057,"version":"4.3.3"},"reference-count":93,"publisher":"Massachusetts Medical Society","issue":"25","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2016,12,22]]},"DOI":"10.1056\/nejmra1600879","type":"journal-article","created":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T17:04:44Z","timestamp":1482339884000},"page":"2468-2479","source":"Crossref","is-referenced-by-count":292,"title":["Neonatal Abstinence Syndrome"],"prefix":"10.1056","volume":"375","author":[{"given":"Karen","family":"McQueen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodie","family":"Murphy-Oikonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","first-page":"141","volume":"2","author":"Finnegan LP","year":"1975","journal-title":"Addict Dis"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2014.114"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3524"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1186\/1940-0640-9-19"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.3951"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2015.36"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1500439"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2015-308948"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2013.05.017"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0000000000000098"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2015.08.013"},{"key":"r012","first-page":"37","volume":"64","author":"Ailes EC","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1556740"},{"key":"r014","first-page":"125","volume":"64","author":"Warren MD","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1505541"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.12927\/hcq.2016.24568"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32834fdc3a"},{"key":"r018","first-page":"35","volume":"10","author":"Jumah NA","year":"2016","journal-title":"Subst Abuse"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34855-1"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-3299"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318256496e"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1374817"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1542\/pir.32-1-5"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1089\/pop.2014.0134"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2888"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1097\/JPN.0000000000000039"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-3212"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005359"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu190"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1177\/2050312114530282"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000207"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/906723"},{"key":"r033","first-page":"147","volume":"19","author":"Siu A","year":"2014","journal-title":"J Pediatr Pharmacol Ther"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000095"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1097\/JPN.0000000000000056"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2767"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.10.004"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0b013e3182266a3a"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.05.010"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2015.12.007"},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.3411"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12513"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.1111\/jlme.12037"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001446"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318288453f"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2013.01.011"},{"key":"r048","doi-asserted-by":"publisher","DOI":"10.1097\/NMC.0000000000000117"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1097\/NMC.0000000000000160"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.10.004"},{"key":"r051","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2012.06.008"},{"key":"r052","doi-asserted-by":"publisher","DOI":"10.1053\/j.nainr.2013.12.004"},{"key":"r053","doi-asserted-by":"publisher","DOI":"10.1097\/JPN.0b013e3181fa13ea"},{"key":"r054","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/951616"},{"key":"r055","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e31815c14ce"},{"key":"r056","doi-asserted-by":"publisher","DOI":"10.1097\/JPN.0000000000000043"},{"key":"r057","doi-asserted-by":"publisher","DOI":"10.1111\/ajad.12388"},{"key":"r058","doi-asserted-by":"publisher","DOI":"10.1177\/000992287501400613"},{"key":"r059","doi-asserted-by":"publisher","DOI":"10.3109\/00952998108999125"},{"key":"r060","doi-asserted-by":"publisher","DOI":"10.1097\/00004703-199804000-00005"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000033"},{"key":"r062","first-page":"e488","volume":"19","author":"Dow K","year":"2012","journal-title":"J Popul Ther Clin Pharmacol"},{"key":"r063","doi-asserted-by":"crossref","first-page":"47","DOI":"10.5055\/jom.2009.0006","volume":"5","author":"Jansson LM","year":"2009","journal-title":"J Opioid Manag"},{"key":"r064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.09.047"},{"key":"r065","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181bc035d"},{"key":"r066","first-page":"165","volume":"40","author":"MacMullen NJ","year":"2014","journal-title":"Pediatr Nurs"},{"key":"r067","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0b013e318225a30c"},{"key":"r068","first-page":"1060","volume":"102","author":"Welle-Strand GK","year":"2013","journal-title":"Acta Paediatr"},{"key":"r069","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6909.2011.01330.x"},{"key":"r070","first-page":"12","volume":"5","author":"Wachman EM","year":"2016","journal-title":"Transl Pediatr"},{"key":"r071","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2015.9992"},{"key":"r072","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1566295"},{"key":"r073","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-2929"},{"key":"r074","doi-asserted-by":"publisher","DOI":"10.1177\/0890334416641909"},{"key":"r075","first-page":"e555","volume":"61","author":"Newman A","year":"2015","journal-title":"Can Fam Physician"},{"key":"r076","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2009.0079"},{"key":"r077","first-page":"9","volume":"10","author":"Balain M","year":"2014","journal-title":"Infant"},{"key":"r078","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2015-308275"},{"key":"r079","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-4036"},{"key":"r080","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2015.07.017"},{"key":"r081","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2013.05.004"},{"key":"r082","first-page":"CD002059","author":"Osborn DA","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"r084","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3835"},{"key":"r085","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.08.032"},{"key":"r086","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.09.038"},{"key":"r087","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.03170.x"},{"key":"r088","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.11.039"},{"key":"r089","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1610"},{"key":"r090","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.116"},{"key":"r091","first-page":"CD002053","author":"Osborn DA","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"r092","doi-asserted-by":"publisher","DOI":"10.1177\/1060028015626438"},{"key":"r093","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-014-0096-y"},{"key":"r094","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/935631"},{"key":"r095","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12603"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMra1600879","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T16:41:40Z","timestamp":1568652100000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMra1600879"}},"subtitle":[],"editor":[{"given":"Dan L.","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,12,22]]},"references-count":93,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2016,12,22]]}},"alternative-id":["10.1056\/NEJMra1600879"],"URL":"https:\/\/doi.org\/10.1056\/nejmra1600879","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,22]]}}}