{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:31:54Z","timestamp":1793309514923,"version":"4.5.0"},"reference-count":106,"publisher":"Massachusetts Medical Society","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2022,12,29]]},"DOI":"10.1056\/nejmra2207599","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T17:01:11Z","timestamp":1672246871000},"page":"2436-2448","source":"Crossref","is-referenced-by-count":268,"title":["Alcohol-Associated Hepatitis"],"prefix":"10.1056","volume":"387","author":[{"given":"Ramon","family":"Bataller","sequence":"first","affiliation":[{"name":"From the Liver Unit, Hospital Cl\u00ednic de Barcelona, Barcelona (R.B.); Departamento de Gastroenterolog\u00eda, Escuela de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago (J.P.A.); the Division of Gastroenterology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, and London Health Sciences Centre, London, ON, Canada (J.P.A.); and the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN (V.H.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8561-396X","authenticated-orcid":false,"given":"Juan Pablo","family":"Arab","sequence":"additional","affiliation":[{"name":"From the Liver Unit, Hospital Cl\u00ednic de Barcelona, Barcelona (R.B.); Departamento de Gastroenterolog\u00eda, Escuela de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago (J.P.A.); the Division of Gastroenterology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, and London Health Sciences Centre, London, ON, Canada (J.P.A.); and the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN (V.H.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay H.","family":"Shah","sequence":"additional","affiliation":[{"name":"From the Liver Unit, Hospital Cl\u00ednic de Barcelona, Barcelona (R.B.); Departamento de Gastroenterolog\u00eda, Escuela de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago (J.P.A.); the Division of Gastroenterology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, and London Health Sciences Centre, London, ON, Canada (J.P.A.); and the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN (V.H.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.11.042"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31310-2"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.06.018"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.05.020"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2019.04.005"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.01.026"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.05.001"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.7683"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.02.022"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.16461"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32141"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32067"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.042"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.01.018"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412278"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.05.011"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.06.019"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197106172842404"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28530"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.10.026"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105703"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.01.037"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.08.011"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-324295"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0805786"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000340"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.05.064"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.10.005"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1123"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02179.x"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.08.057"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.09.002"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30617"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2020.100220"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1742-x"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.01.056"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24843-w"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11004-3"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.05.041"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25614"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27779"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.01.042"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32110"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308410"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2021.03.001"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1306421"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.05.029"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000912"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29080"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.11.050"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31256"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25328"},{"key":"e_1_3_4_54_2","doi-asserted-by":"publisher","DOI":"10.14740\/gr1526"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.062"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.12.019"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90401-8"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20503"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.02104.x"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.050781"},{"key":"e_1_3_4_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.11.017"},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001596"},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21607"},{"key":"e_1_3_4_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.539"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29338"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20688"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21278"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03232.x"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agx100"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2021.10.005"},{"key":"e_1_3_4_71_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-021-00527-0"},{"key":"e_1_3_4_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61814-5"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.04.048"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.10.026"},{"key":"e_1_3_4_75_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31042"},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.08.001"},{"key":"e_1_3_4_77_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.13014"},{"key":"e_1_3_4_78_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.276300"},{"key":"e_1_3_4_79_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.224097"},{"key":"e_1_3_4_80_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1101214"},{"key":"e_1_3_4_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.05.030"},{"key":"e_1_3_4_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.09.011"},{"key":"e_1_3_4_83_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31984"},{"key":"e_1_3_4_84_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-021-06864-z"},{"key":"e_1_3_4_85_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32378"},{"key":"e_1_3_4_86_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13586"},{"key":"e_1_3_4_87_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001831"},{"key":"e_1_3_4_88_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.04.009"},{"key":"e_1_3_4_89_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16143"},{"key":"e_1_3_4_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.11.024"},{"key":"e_1_3_4_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00430-1"},{"key":"e_1_3_4_92_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16936"},{"key":"e_1_3_4_93_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30478"},{"key":"e_1_3_4_94_2","doi-asserted-by":"publisher","DOI":"10.1002\/cld.756"},{"key":"e_1_3_4_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.04.040"},{"key":"e_1_3_4_96_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.17059"},{"key":"e_1_3_4_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.04.026"},{"key":"e_1_3_4_98_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.26324"},{"key":"e_1_3_4_99_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.5283"},{"key":"e_1_3_4_100_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31046"},{"key":"e_1_3_4_101_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.154"},{"key":"e_1_3_4_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2020.100139"},{"key":"e_1_3_4_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.10.029"},{"key":"e_1_3_4_104_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32478"},{"key":"e_1_3_4_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30326-7"},{"key":"e_1_3_4_106_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32016"},{"key":"e_1_3_4_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2022.100325"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMra2207599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T19:02:24Z","timestamp":1749668544000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMra2207599"}},"subtitle":[],"editor":[{"given":"C. Corey","family":"Hardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,12,29]]},"references-count":106,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2022,12,29]]}},"alternative-id":["10.1056\/NEJMra2207599"],"URL":"https:\/\/doi.org\/10.1056\/nejmra2207599","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,29]]}}}