{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T20:29:34Z","timestamp":1793046574760,"version":"4.5.0"},"reference-count":77,"publisher":"Massachusetts Medical Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2026,7,9]]},"DOI":"10.1056\/nejmra2506111","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:00:26Z","timestamp":1783544426000},"page":"162-174","source":"Crossref","is-referenced-by-count":4,"title":["Nutrition Therapy in Critically Ill Adults"],"prefix":"10.1056","volume":"395","author":[{"given":"Jayshil J.","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen A.","family":"McClave","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Louisville School of Medicine, Louisville, KY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.08.037"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeu187"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.4065\/78.12.1471"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-04253-0"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00090011"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2017-211073"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/shk.0b013e31805569df"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30036-0"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(15)00427-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.113"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-024-00954-4"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/0884533615609904"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607115621863"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/0884533613510948"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.5124"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409860"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32146-3"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.137"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1502826"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(15)00418-X"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1811687"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(23)00092-9"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02469-2"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01304-7"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.9110"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-010-1856-y"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.196377"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2539"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu17010010"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2005.10.010"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2005.03.006"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607115585142"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12659"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.08.017"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4880-3"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.005074"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31820a905a"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.088609"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.086322"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2016.05.004"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607114528980"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1782"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu12113518"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.6.1603"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/132.9.2717"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2023.07.011"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2267"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuaf042"},{"key":"e_1_3_3_50_2","first-page":"165","article-title":"Enteral nutrition in septic shock: a call for a paradigm shift.","volume":"30","author":"Patel JJ","year":"2024","unstructured":"Patel JJ, Lopez-Delgado JC, Stoppe C, McClave SA. Enteral nutrition in septic shock: a call for a paradigm shift. Curr Opin Crit Care 2024;30:165-171.38441124","journal-title":"Curr Opin Crit Care"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10320"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1177\/0884533617691245"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202112-2780OC"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04663-8"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2212159"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.02.008"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.17433"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04783-1"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2406954"},{"key":"e_1_3_3_60_2","first-page":"463","article-title":"Gastrointestinal function in critically ill patients.","volume":"26","author":"Reintam Blaser A","year":"2023","unstructured":"Reintam Blaser A, Bachmann KF, Deane AM. Gastrointestinal function in critically ill patients. Curr Opin Clin Nutr Metab Care 2023;26:463-469.37389469","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1136\/flgastro-2016-100722"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2404245"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10646"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000006174"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10474"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004712"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000153413.46627.3A"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.13124"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(23)00237-0"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2748"},{"key":"e_1_3_3_71_2","doi-asserted-by":"crossref","unstructured":"Jangda M Patel J Gill J et al. NutriSighT: interpretable transformer model for dynamic prediction of hypocaloric enteral nutrition in mechanically ventilated patients. January 6 2025 (https:\/\/www.medrxiv.org\/content\/10.1101\/2025.01.06.25320067v1). preprint.","DOI":"10.1101\/2025.01.06.25320067"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03208-7"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.05.008"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000006537"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2104669"},{"issue":"1","key":"e_1_3_3_76_2","first-page":"E118","article-title":"Resistance training reduces the acute exercise-induced increase in muscle protein turnover.","volume":"276","author":"Phillips SM","year":"1999","unstructured":"Phillips SM, Tipton KD, Ferrando AA, Wolfe RR. Resistance training reduces the acute exercise-induced increase in muscle protein turnover. Am J Physiol 1999;276(1):E118-E124.9886957","journal-title":"Am J Physiol"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4711-6"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-021-01492-6"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMra2506111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:00:38Z","timestamp":1783544438000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMra2506111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,9]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,7,9]]}},"alternative-id":["10.1056\/NEJMra2506111"],"URL":"https:\/\/doi.org\/10.1056\/nejmra2506111","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,9]]}}}