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One of the innovations of the protocol is the opportunity to reconstruct an interpolated micro-CT image under the same angle as the physical cutting angle of the microscopic sections. Also, a novel thresholding method is developed based on matching micro-CT and microscopic images. In this study, titanium porous structures are assessed as proof of principle. It is concluded for these structures that micro-CT visualizes 89% of the total amount of voxels (solid and pore) correctly. However, 8% represents an overestimation of the real structure and 3% are real structural features not visualized by micro-CT. When exclusively focusing on the solid fraction in both the micro-CT and microscopic images, only an overestimation of about 5% is found.<\/jats:p>","DOI":"10.1063\/1.2838584","type":"journal-article","created":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:18:50Z","timestamp":1201825130000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":91,"title":["Validation of x-ray microfocus computed tomography as an imaging tool for porous structures"],"prefix":"10.1063","volume":"79","author":[{"given":"G.","family":"Kerckhofs","sequence":"first","affiliation":[{"name":"Katholieke Universiteit Leuven 1 Department of Metallurgy and Materials Engineering, , Kasteelpark Arenberg 44-bus 2450, B-3001 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schrooten","sequence":"additional","affiliation":[{"name":"Katholieke Universiteit Leuven 1 Department of Metallurgy and Materials Engineering, , Kasteelpark Arenberg 44-bus 2450, B-3001 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Van Cleynenbreugel","sequence":"additional","affiliation":[{"name":"Katholieke Universiteit Leuven 2 Division of Biomechanics and Engineering Design, , Celestijnenlaan 300C, B-3001 Leuven, Belgium"},{"name":"Materialise Dental NV 3 , Technologielaan 15, B-3001 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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