{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:51:54Z","timestamp":1753872714415,"version":"3.41.2"},"reference-count":6,"publisher":"AIP Publishing","issue":"12","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2008,12,1]]},"abstract":"<jats:p>We have developed a compact, isolated, physiological, constant-current stimulator that is powered and controlled by a universal serial bus (USB) interface. The stimulator is designed to be used in ex vivo cardiac experiments but is suitable for a wide variety of settings. The cost and features compare very favorably with commercial stimulators usually used in research and student laboratories. In addition to being USB powered, other novel aspects of our stimulator include the ability to produce large currents, up to 100 mA through a typical 1\u2002k\u03a9 load, by means of a single high-voltage dc-to-dc converter; user-specified variable period, magnitude, and duration of complex monophasic or biphasic sequences; and easy integration via hardware or software into existing experimental setups.<\/jats:p>","DOI":"10.1063\/1.3030861","type":"journal-article","created":{"date-parts":[[2008,12,10]],"date-time":"2008-12-10T01:05:22Z","timestamp":1228871122000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["Universal serial bus powered and controlled isolated constant-current physiological stimulator"],"prefix":"10.1063","volume":"79","author":[{"given":"Mark R.","family":"Holcomb","sequence":"first","affiliation":[{"name":"Vanderbilt University 1 Department of Physics and Astronomy, , Nashville, Tennessee 37235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robel Y.","family":"Bekele","sequence":"additional","affiliation":[{"name":"Vanderbilt University 1 Department of Physics and Astronomy, , Nashville, Tennessee 37235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo A.","family":"Lima","sequence":"additional","affiliation":[{"name":"Vanderbilt University 2 Department of Biomedical Engineering, , Nashville, Tennessee 37235, USA"},{"name":"Vanderbilt University 3 Vanderbilt Institute for Integrative Biosystems Research and Education, , Nashville, Tennessee 37235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Wikswo","sequence":"additional","affiliation":[{"name":"Vanderbilt University 1 Department of Physics and Astronomy, , Nashville, Tennessee 37235, USA"},{"name":"Vanderbilt University 2 Department of Biomedical Engineering, , Nashville, Tennessee 37235, USA"},{"name":"Vanderbilt University 3 Vanderbilt Institute for Integrative Biosystems Research and Education, , Nashville, Tennessee 37235, USA"},{"name":"Vanderbilt University 4 Department of Molecular Physiology and Biophysics, , Nashville, Tennessee 37235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"317","published-online":{"date-parts":[[2008,12,9]]},"reference":[{"key":"2023070403071323700_c1","first-page":"A30","volume":"3","year":"2004","journal-title":"J. Undergrad. Neurosci. Ed."},{"key":"2023070403071323700_c2","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1590\/S0100-879X1999000600013","volume":"32","year":"1999","journal-title":"Braz. J. Med. Biol. Res."},{"key":"2023070403071323700_c3","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1109\/10.650352","volume":"45","year":"1998","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"2023070403071323700_c4","unstructured":"See EPAPS Document No. E-RSINAK-79-009812 for a supplement that gives additional details and discussion of the stimulator. For more information on EPAPS, see http:\/\/www.aip.org\/pubservs\/epaps.html."},{"key":"2023070403071323700_c5","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1109\/TBME.2007.912417","volume":"55","year":"2008","journal-title":"IEEE Trans. Biomed. 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Cardiol."}],"container-title":["Review of Scientific Instruments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/aip\/rsi\/article-pdf\/doi\/10.1063\/1.3030861\/9918350\/126103_1_online.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/aip\/rsi\/article-pdf\/doi\/10.1063\/1.3030861\/9918350\/126103_1_online.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T03:07:22Z","timestamp":1688440042000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/rsi\/article\/79\/12\/126103\/353883\/Universal-serial-bus-powered-and-controlled"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,1]]},"references-count":6,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12,1]]}},"URL":"https:\/\/doi.org\/10.1063\/1.3030861","relation":{},"ISSN":["0034-6748","1089-7623"],"issn-type":[{"type":"print","value":"0034-6748"},{"type":"electronic","value":"1089-7623"}],"subject":[],"published-other":{"date-parts":[[2008,12]]},"published":{"date-parts":[[2008,12,1]]},"article-number":"126103"}}