{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:58:42Z","timestamp":1770965922666,"version":"3.50.1"},"reference-count":108,"publisher":"AIP Publishing","issue":"23","funder":[{"name":"Russian Foundation for Basic Research","award":["12-03-00223-a"],"award-info":[{"award-number":["12-03-00223-a"]}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,6,21]]},"abstract":"<jats:p>The empty-level structures and formation of negative ion states via resonance attachment of low-energy (0\u201315 eV) electrons into vacant molecular orbitals in a series of non-steroidal anti-inflammatory drugs (NSAIDs), namely aspirin, paracetamol, phenacetin, and ibuprofen, were investigated in vacuo by electron transmission and dissociative electron attachment (DEA) spectroscopies, with the aim to model the behavior of these antipyretic agents under reductive conditions in vivo. The experimental findings are interpreted with the support of density functional theory calculations. The negative and neutral fragments formed by DEA in the gas phase display similarities with the main metabolites of these commonly used NSAIDs generated in vivo by the action of cytochrome P450 enzymes, as well as with several known active agents. It is concluded that xenobiotic molecules which possess pronounced electron-accepting properties could in principle follow metabolic pathways which parallel the gas-phase dissociative decay channels observed in the DEA spectra at incident electron energies below 1 eV. Unwanted side effects as, e.g., hepatoxicity or carcinogenicity produced by the NSAIDs under study in human organism are discussed within the \u201cfree radical model\u201d framework, reported earlier to describe the toxic action of the well-known model toxicant carbon tetrachloride.<\/jats:p>","DOI":"10.1063\/1.4727854","type":"journal-article","created":{"date-parts":[[2012,6,19]],"date-time":"2012-06-19T22:46:13Z","timestamp":1340145973000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Electron attachment to antipyretics: Possible implications of their metabolic pathways"],"prefix":"10.1063","volume":"136","author":[{"given":"Stanislav A.","family":"Pshenichnyuk","sequence":"first","affiliation":[{"name":"Institute of Molecule and Crystal Physics 1 , Ufa Research Centre, Russian Academy of Sciences, Prospekt Oktyabrya 151, 450075 Ufa, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Modelli","sequence":"additional","affiliation":[{"name":"Universit\u00e1 di Bologna 2 Dipartimento di Chimica \u201cG. Ciamician,\u201d , via Selmi 2, 40126 Bologna, Italy and Centro Interdipartimentale di Ricerca in Scienze Ambientali (CIRSA), , via S. Alberto 163, 48123 Ravenna, Italy"},{"name":"Universit\u00e1 di Bologna 2 Dipartimento di Chimica \u201cG. Ciamician,\u201d , via Selmi 2, 40126 Bologna, Italy and Centro Interdipartimentale di Ricerca in Scienze Ambientali (CIRSA), , via S. Alberto 163, 48123 Ravenna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"317","published-online":{"date-parts":[[2012,6,19]]},"reference":[{"key":"2023070122585132400_c1","volume-title":"The Organic Chemistry of Drug Design and Drug Action","year":"2004","edition":"2nd ed."},{"key":"2023070122585132400_c2","volume-title":"Introduction to Drug Metabolism","year":"2001","edition":"3rd ed."},{"key":"2023070122585132400_c3","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1021\/jm021104i","volume":"46","year":"2003","journal-title":"J. Med. Chem."},{"key":"2023070122585132400_c4","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/nrd2173","volume":"6","year":"2007","journal-title":"Nat. Rev. Drug Discovery"},{"key":"2023070122585132400_c5","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1021\/tx200148a","volume":"24","year":"2011","journal-title":"Chem. Res. Toxicol."},{"key":"2023070122585132400_c6","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S1359-6446(03)02971-4","volume":"9","year":"2004","journal-title":"Drug Discovery Today"},{"key":"2023070122585132400_c7","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1146\/annurev-pharmtox-010611-134748","volume":"52","year":"2012","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"2023070122585132400_c8","doi-asserted-by":"publisher","first-page":"1662","DOI":"10.1126\/science.1069492","volume":"295","year":"2002","journal-title":"Science"},{"key":"2023070122585132400_c9","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1146\/annurev.arplant.54.031902.135014","volume":"54","year":"2003","journal-title":"Annu. Rev. Plant Biol."},{"key":"2023070122585132400_c10","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/mas.20108","volume":"26","year":"2007","journal-title":"Mass Spectrom. Rev."},{"key":"2023070122585132400_c11","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s11306-008-0152-0","volume":"5","year":"2009","journal-title":"Metabolomics"},{"key":"2023070122585132400_c12","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1038\/2121460a0","volume":"212","year":"1966","journal-title":"Nature (London)"},{"key":"2023070122585132400_c13","doi-asserted-by":"publisher","first-page":"2S","DOI":"10.1016\/S0002-9343(97)00203-9","volume":"104","year":"1998","journal-title":"Am. J. Med."},{"key":"2023070122585132400_c14","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1021\/cr0307143","volume":"105","year":"2005","journal-title":"Chem. Rev."},{"key":"2023070122585132400_c15","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1126\/science.1193478","volume":"330","year":"2010","journal-title":"Science"},{"key":"2023070122585132400_c16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1046\/j.1365-2125.1998.00721.x","volume":"45","year":"1998","journal-title":"Br. J. Clin. Pharmacol."},{"key":"2023070122585132400_c17","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1146\/annurev.bi.44.070175.002113","volume":"44","year":"1975","journal-title":"Annu. Rev. Biochem."},{"key":"2023070122585132400_c18","doi-asserted-by":"publisher","first-page":"3569","DOI":"10.1073\/pnas.0830019100","volume":"100","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"2023070122585132400_c19","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1021\/cr9002193","volume":"110","year":"2010","journal-title":"Chem. Rev."},{"key":"2023070122585132400_c20","doi-asserted-by":"publisher","first-page":"3947","DOI":"10.1021\/cr020443g","volume":"104","year":"2004","journal-title":"Chem. Rev."},{"key":"2023070122585132400_c21","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/B0-12-443710-9\/00143-5","volume":"1","year":"2004","journal-title":"Encyclopedia Biol. Chem."},{"key":"2023070122585132400_c22","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1021\/ar00033a001","volume":"26","year":"1993","journal-title":"Acc. Chem. Res."},{"key":"2023070122585132400_c23","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1149\/2.F07024IF","volume":"11","year":"2002","journal-title":"Electrochem. Soc. Interface"},{"key":"2023070122585132400_c24","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1039\/b300085k","volume":"34","year":"2005","journal-title":"Chem. Soc. Rev."},{"key":"2023070122585132400_c25","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1103\/PhysRevA.5.1672","volume":"5","year":"1972","journal-title":"Phys. Rev. A"},{"key":"2023070122585132400_c26","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1103\/RevModPhys.45.423","volume":"45","year":"1973","journal-title":"Rev. Mod. Phys."},{"key":"2023070122585132400_c27","volume-title":"Gaseous Molecular Ions. An Introduction to Elementary Processes Induced by Ionization","year":"1992"},{"key":"2023070122585132400_c28","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/978-1-4419-1352-4_4","volume":"203","year":"2010","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"2023070122585132400_c29","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/978-1-4419-0032-6_2","volume":"201","year":"2009","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"2023070122585132400_c30","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2174\/1381612003401046","volume":"6","year":"2000","journal-title":"Curr. Pharm. Des."},{"key":"2023070122585132400_c31","doi-asserted-by":"publisher","first-page":"2705","DOI":"10.2174\/0929867033456314","volume":"10","year":"2003","journal-title":"Curr. Med. Chem."},{"key":"2023070122585132400_c32","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.mehy.2004.07.021","volume":"64","year":"2005","journal-title":"Med. Hypotheses"},{"key":"2023070122585132400_c33","doi-asserted-by":"publisher","first-page":"212","DOI":"10.2307\/3575502","volume":"86","year":"1981","journal-title":"Radiat. Res."},{"key":"2023070122585132400_c34","doi-asserted-by":"publisher","first-page":"8521","DOI":"10.1021\/jp0357323","volume":"107","year":"2003","journal-title":"J. Phys. Chem. A"},{"key":"2023070122585132400_c35","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0163-7258(89)90050-8","volume":"43","year":"1989","journal-title":"Pharmacol. Ther."},{"key":"2023070122585132400_c36","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/0748-5514(85)90026-1","volume":"1","year":"1985","journal-title":"J. Free Radic. Biol. Med."},{"key":"2023070122585132400_c37","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1080\/10590500701569398","volume":"25","year":"2007","journal-title":"J. Environ. Sci. Health [C]"},{"key":"2023070122585132400_c38","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1098\/rstb.1985.0169","volume":"311","year":"1985","journal-title":"Philos. Trans. R. Soc. London, Ser. B"},{"key":"2023070122585132400_c39","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.chemphyslip.2009.02.006","volume":"159","year":"2009","journal-title":"Chem. Phys. Lipids"},{"key":"2023070122585132400_c40","first-page":"111","volume":"56","year":"2001","journal-title":"Z Naturforsch. C"},{"key":"2023070122585132400_c41","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/0009-3084(87)90063-6","volume":"45","year":"1987","journal-title":"Chem. Phys. Lipids"},{"key":"2023070122585132400_c42","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0002-9343(99)00365-4","volume":"107","year":"1999","journal-title":"Am. J. Med."},{"key":"2023070122585132400_c43","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1177\/014107688607901014","volume":"79","year":"1986","journal-title":"J. R. Soc. Med."},{"key":"2023070122585132400_c44","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1136\/adc.85.5.351","volume":"85","year":"2001","journal-title":"Arch. Dis. Child"},{"key":"2023070122585132400_c45","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1093\/qjmed\/95.9.609","volume":"95","year":"2002","journal-title":"Q. J. Med."},{"key":"2023070122585132400_c46","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1124\/dmd.31.12.1499","volume":"31","year":"2003","journal-title":"Drug Metab. Dispos."},{"key":"2023070122585132400_c47","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/0041-008X(59)90108-5","volume":"1","year":"1959","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"2023070122585132400_c48","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1126\/science.204.4389.130","volume":"204","year":"1979","journal-title":"Science"},{"key":"2023070122585132400_c49","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1093\/toxsci\/50.1.82","volume":"50","year":"1999","journal-title":"Toxicol. Sci."},{"key":"2023070122585132400_c50","doi-asserted-by":"crossref","first-page":"291S","DOI":"10.1111\/j.1365-2125.1980.tb01812.x","volume":"10","year":"1980","journal-title":"Br. J. Clin. Pharmacol."},{"key":"2023070122585132400_c51","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S0026-895X(25)15108-0","volume":"26","year":"1984","journal-title":"Mol. Pharmacol."},{"key":"2023070122585132400_c52","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S0304-3940(00)01294-5","volume":"289","year":"2000","journal-title":"Neurosci. Lett."},{"key":"2023070122585132400_c53","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1111\/j.1553-2712.2000.tb02278.x","volume":"7","year":"2000","journal-title":"Acad. Emerg. Med."},{"key":"2023070122585132400_c54","doi-asserted-by":"publisher","first-page":"13345","DOI":"10.1021\/jp076553e","volume":"111","year":"2007","journal-title":"J. Phys. Chem. B"},{"key":"2023070122585132400_c55","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/BFb0048262","volume":"127","year":"1996","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"2023070122585132400_c56","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1146\/annurev.pa.23.040183.002405","volume":"23","year":"1983","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"2023070122585132400_c57","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/0009-2614(82)83539-2","volume":"86","year":"1982","journal-title":"Chem. Phys. Lett."},{"key":"2023070122585132400_c58","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/0009-2614(89)80048-X","volume":"163","year":"1989","journal-title":"Chem. Phys. Lett."},{"key":"2023070122585132400_c59","volume-title":"Negative Ion Mass Spectrometry in Organic Chemistry","year":"1981"},{"key":"2023070122585132400_c60","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1255\/ejms.650","volume":"10","year":"2004","journal-title":"Eur. J. Mass Spectrom."},{"key":"2023070122585132400_c61","year":"2009"},{"key":"2023070122585132400_c62","doi-asserted-by":"publisher","first-page":"5648","DOI":"10.1063\/1.464913","volume":"98","year":"1993","journal-title":"J. Chem. Phys."},{"key":"2023070122585132400_c63","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/S0031-8914(34)90011-2","volume":"1","year":"1934","journal-title":"Physica"},{"key":"2023070122585132400_c64","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1021\/cr00079a004","volume":"87","year":"1987","journal-title":"Chem. Rev."},{"key":"2023070122585132400_c65","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1021\/j100052a020","volume":"98","year":"1994","journal-title":"J. Phys. Chem."},{"key":"2023070122585132400_c66","doi-asserted-by":"publisher","first-page":"8893","DOI":"10.1063\/1.459228","volume":"93","year":"1990","journal-title":"J. Chem. Phys."},{"key":"2023070122585132400_c67","doi-asserted-by":"publisher","first-page":"2923","DOI":"10.1039\/b304083f","volume":"5","year":"2003","journal-title":"Phys. Chem. Chem. Phys."},{"key":"2023070122585132400_c68","doi-asserted-by":"publisher","first-page":"17751","DOI":"10.1021\/jp0628784","volume":"110","year":"2006","journal-title":"J. Phys. Chem. B"},{"key":"2023070122585132400_c69","doi-asserted-by":"publisher","first-page":"4157","DOI":"10.1039\/b923202h","volume":"12","year":"2010","journal-title":"Phys. Chem. Chem. Phys."},{"key":"2023070122585132400_c70","doi-asserted-by":"publisher","first-page":"8986","DOI":"10.1021\/jp061845l","volume":"100","year":"2006","journal-title":"J. Phys. Chem. A"},{"key":"2023070122585132400_c71","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1021\/jo001241s","volume":"66","year":"2001","journal-title":"J. Org. Chem."},{"key":"2023070122585132400_c72","doi-asserted-by":"publisher","first-page":"7933","DOI":"10.1021\/jo201389d","volume":"76","year":"2011","journal-title":"J. Org. Chem."},{"key":"2023070122585132400_c73","first-page":"57","volume":"6","year":"1997","journal-title":"Trends Chem. Phys."},{"key":"2023070122585132400_c74","doi-asserted-by":"publisher","first-page":"1843011","DOI":"10.1063\/1.3658372","volume":"135","year":"2011","journal-title":"J. Chem. Phys."},{"key":"2023070122585132400_c75","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.ijms.2010.05.025","volume":"294","year":"2010","journal-title":"Int. J. Mass Spectrom."},{"key":"2023070122585132400_c76","unstructured":"See supplementary material at http:\/\/dx.doi.org\/10.1063\/1.4727854 for currents of mass-selected negative ions formed by DEA to I and II with low relative intensity as well as metastable ions detected in I."},{"key":"2023070122585132400_c77","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1038\/355796a0","volume":"355","year":"1992","journal-title":"Nature (London)"},{"key":"2023070122585132400_c78","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1021\/cr00079a003","volume":"87","year":"1987","journal-title":"Chem. Rev."},{"key":"2023070122585132400_c79","doi-asserted-by":"publisher","first-page":"13148","DOI":"10.1021\/jp9605663","volume":"100","year":"1996","journal-title":"J. Phys. Chem."},{"key":"2023070122585132400_c80","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.cplett.2005.11.095","volume":"419","year":"2006","journal-title":"Chem. Phys. Lett."},{"key":"2023070122585132400_c81","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1021\/jp210224j","volume":"116","year":"2012","journal-title":"J. Phys. Chem. A"},{"key":"2023070122585132400_c82","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1063\/1.481963","volume":"113","year":"2000","journal-title":"J. Chem. Phys."},{"key":"2023070122585132400_c83","doi-asserted-by":"publisher","first-page":"239","DOI":"10.3109\/00498258609043527","volume":"16","year":"1986","journal-title":"Xenobiotica"},{"key":"2023070122585132400_c84","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0049-3848(03)00379-7","volume":"110","year":"2003","journal-title":"Thromb. Res."},{"key":"2023070122585132400_c85","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/0006-2952(88)90729-0","volume":"37","year":"1988","journal-title":"Biochem. Pharmacol."},{"key":"2023070122585132400_c86","doi-asserted-by":"publisher","first-page":"6647","DOI":"10.1021\/ja071355m","volume":"129","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"2023070122585132400_c87","doi-asserted-by":"publisher","first-page":"18783","DOI":"10.1073\/pnas.1012381107","volume":"107","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"2023070122585132400_c88","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1126\/science.1099320","volume":"305","year":"2004","journal-title":"Science"},{"key":"2023070122585132400_c89","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0022-3565(25)20745-5","volume":"278","year":"1996","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"2023070122585132400_c90","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1046\/j.1365-2036.2000.00723.x","volume":"14","year":"2000","journal-title":"Aliment. Pharmacol. Ther."},{"key":"2023070122585132400_c91","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1006\/abbi.1993.1452","volume":"305","year":"1993","journal-title":"Arch. Biochem. Biophys."},{"key":"2023070122585132400_c92","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/0167-4838(91)90164-U","volume":"1078","year":"1991","journal-title":"Biochim. Biophys. Acta"},{"key":"2023070122585132400_c93","article-title":"Acetaminophen","volume-title":"Goldfrank's Manual of Toxicologic Emergencies","author":"Hoffman","year":"2007"},{"key":"2023070122585132400_c94","doi-asserted-by":"publisher","first-page":"31405","DOI":"10.1074\/jbc.M501489200","volume":"280","year":"2005","journal-title":"J. Biol. Chem."},{"key":"2023070122585132400_c95","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1136\/ard.2011.200087","volume":"71","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"2023070122585132400_c96","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1097\/00045391-200501000-00008","volume":"12","year":"2005","journal-title":"Am. J. Ther."},{"key":"2023070122585132400_c97","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/ncomms1559","volume":"2","year":"2011","journal-title":"Nature Commun."},{"key":"2023070122585132400_c98","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S0090-9556(24)13665-3","volume":"28","year":"2000","journal-title":"Drug Metab. Dispos."},{"key":"2023070122585132400_c99","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1073\/pnas.81.5.1327","volume":"81","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"2023070122585132400_c100","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S0021-9258(18)48355-X","volume":"267","year":"1992","journal-title":"J. Biol. Chem."},{"key":"2023070122585132400_c101","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1289\/ehp.834971","volume":"49","year":"1983","journal-title":"Environ. Health Perspect."},{"key":"2023070122585132400_c102","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3109\/00498258709047181","volume":"17","year":"1987","journal-title":"Xenobiotica"},{"key":"2023070122585132400_c103","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.jpba.2007.12.035","volume":"47","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"key":"2023070122585132400_c104","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0006-2952(97)00143-3","volume":"54","year":"1997","journal-title":"Biochem. Pharmacol."},{"key":"2023070122585132400_c105","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/0190-9622(92)70018-B","volume":"26","year":"1992","journal-title":"J. Am. Acad. Dermatol."},{"key":"2023070122585132400_c106","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1046\/j.0022-3042.2002.00744.x","volume":"80","year":"2002","journal-title":"J. Neurochem."},{"key":"2023070122585132400_c107","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1038\/ni1202-1129","volume":"3","year":"2002","journal-title":"Nat. Immunol."},{"key":"2023070122585132400_c108","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1146\/annurev.pharmtox.37.1.517","volume":"37","year":"1997","journal-title":"Annu. Rev. Pharmacol. Toxicol."}],"container-title":["The Journal of Chemical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/aip\/jcp\/article-pdf\/doi\/10.1063\/1.4727854\/15451654\/234307_1_online.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/aip\/jcp\/article-pdf\/doi\/10.1063\/1.4727854\/15451654\/234307_1_online.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T06:51:33Z","timestamp":1743576693000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/jcp\/article\/136\/23\/234307\/315953\/Electron-attachment-to-antipyretics-Possible"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,19]]},"references-count":108,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2012,6,21]]}},"URL":"https:\/\/doi.org\/10.1063\/1.4727854","relation":{},"ISSN":["0021-9606","1089-7690"],"issn-type":[{"value":"0021-9606","type":"print"},{"value":"1089-7690","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2012,6,21]]},"published":{"date-parts":[[2012,6,19]]},"article-number":"234307"}}