{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T03:13:04Z","timestamp":1768533184014,"version":"3.49.0"},"reference-count":42,"publisher":"AIP Publishing","issue":"3","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,1,21]]},"abstract":"<jats:p>Calcium phosphate based biomaterials are extensively used in the context of tissue engineering: small changes in composition can lead to significant changes in properties allowing their use in a wide range of applications. Samples of composition (Al2O3)x(Na2O)0.11-x(CaO)0.445(P2O5)0.445, where x = 0, 0.03, 0.05, and 0.08, were prepared by melt quenching. The atomic-scale structure has been studied using neutron diffraction and solid state 27Al MAS NMR, and these data have been rationalised with the determined density of the final glass product. With increasing aluminium concentration the density increases initially, but beyond about 3 mol. % Al2O3 the density starts to decrease. Neutron diffraction data show a concomitant change in the aluminium speciation, which is confirmed by 27Al MAS NMR studies. The NMR data reveal that aluminium is present in 4, 5, and 6-fold coordination and that the relative concentrations of these environments change with increasing aluminium concentration. Materials containing aluminium in 6-fold coordination tend to have higher densities than analogous materials with the aluminium found in 4-fold coordination. Thus, the density changes may readily be explained in terms of an increase in the relative concentration of 4-coordinated aluminium at the expense of 6-fold aluminium as the Al2O3 content is increased beyond 3 mol. %.<\/jats:p>","DOI":"10.1063\/1.4774330","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T23:26:11Z","timestamp":1358378771000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Structural study of Al2O3-Na2O-CaO-P2O5 bioactive glasses as a function of aluminium content"],"prefix":"10.1063","volume":"138","author":[{"given":"J. M.","family":"Smith","sequence":"first","affiliation":[{"name":"University of Kent 1 School of Physical Sciences, , Canterbury CT2 7NH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. P.","family":"King","sequence":"additional","affiliation":[{"name":"University of Warwick 2 Department of Physics, , Coventry CV4 7AL, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. R.","family":"Barney","sequence":"additional","affiliation":[{"name":"University of Nottingham 3 Electrical Systems and Optics Research Division, Faculty of Engineering, , Nottingham NG7 2RD, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. V.","family":"Hanna","sequence":"additional","affiliation":[{"name":"University of Warwick 2 Department of Physics, , Coventry CV4 7AL, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J.","family":"Newport","sequence":"additional","affiliation":[{"name":"University of Kent 1 School of Physical Sciences, , Canterbury CT2 7NH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Pickup","sequence":"additional","affiliation":[{"name":"University of Kent 1 School of Physical Sciences, , Canterbury CT2 7NH, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"317","published-online":{"date-parts":[[2013,1,15]]},"reference":[{"key":"2023062520492219500_c1","doi-asserted-by":"publisher","first-page":"035109","DOI":"10.1088\/0953-8984\/21\/3\/035109","volume":"21","year":"2009","journal-title":"J. Phys.: Condens. Matter"},{"key":"2023062520492219500_c2","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/j.jnoncrysol.2009.04.016","volume":"355","year":"2009","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c3","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1111\/j.1551-2916.2010.04292.x","volume":"94","year":"2011","journal-title":"J. Am. Ceram. Soc."},{"key":"2023062520492219500_c4","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/S0022-3093(99)00645-6","volume":"263\u2013264","year":"2000","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c5","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1039\/a608325k","volume":"7","year":"1997","journal-title":"J. Mater. Chem."},{"key":"2023062520492219500_c6","volume-title":"Biomaterials, Artificial Organs and Tissue Engineering","author":"Hench","year":"2005"},{"key":"2023062520492219500_c7","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/S0142-9612(03)00546-5","volume":"25","year":"2004","journal-title":"Biomaterials"},{"key":"2023062520492219500_c8","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1016\/j.ceramint.2007.05.016","volume":"34","year":"2008","journal-title":"Ceram. Int."},{"key":"2023062520492219500_c9","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1002\/pssa.200824426","volume":"206","year":"2009","journal-title":"Phys. Status Solidi A"},{"key":"2023062520492219500_c10","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1021\/ic0499704","volume":"44","year":"2005","journal-title":"Inorg. Chem."},{"key":"2023062520492219500_c11","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/S0022-3093(99)00625-0","volume":"263\u2013264","year":"2000","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c12","doi-asserted-by":"publisher","first-page":"4777","DOI":"10.1039\/b709955j","volume":"17","year":"2007","journal-title":"J. Mater. Chem."},{"key":"2023062520492219500_c13","doi-asserted-by":"publisher","first-page":"485403","DOI":"10.1088\/0953-8984\/22\/48\/485403","volume":"22","year":"2010","journal-title":"J. Phys.: Condens. Matter"},{"key":"2023062520492219500_c14","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1111\/j.1151-2916.2003.tb00017.x","volume":"86","year":"2003","journal-title":"J. Am. Ceram. Soc."},{"key":"2023062520492219500_c15","doi-asserted-by":"publisher","first-page":"9510","DOI":"10.1021\/jp972147r","volume":"101","year":"1997","journal-title":"J. Phys. Chem. B"},{"key":"2023062520492219500_c16","doi-asserted-by":"publisher","first-page":"S2413","DOI":"10.1088\/0953-8984\/15\/31\/316","volume":"15","year":"2003","journal-title":"J. Phys.: Condens. Matter"},{"key":"2023062520492219500_c17","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1111\/j.1151-2916.2001.tb00785.x","volume":"84","year":"2001","journal-title":"J. Am. Ceram. Soc."},{"key":"2023062520492219500_c18","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/S1386-1425(98)00316-3","volume":"55","year":"1999","journal-title":"Spectrochim. Acta, Part A"},{"key":"2023062520492219500_c19","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.ssnmr.2007.07.004","volume":"32","year":"2007","journal-title":"Solid State Nucl. Magn. Reson."},{"key":"2023062520492219500_c20","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0022-3093(99)00606-7","volume":"261","year":"2000","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c21","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.nima.2005.07.053","volume":"551","year":"2005","journal-title":"Nucl. Instrum. Methods Phys. Res. A"},{"key":"2023062520492219500_c22","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1088\/0022-3719\/2\/2\/305","volume":"2","year":"1969","journal-title":"J. Phys. C"},{"key":"2023062520492219500_c23","volume-title":"Materials Science and Technology","author":"Zarzycki","year":"1991"},{"key":"2023062520492219500_c24","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1016\/j.jnoncrysol.2010.03.006","volume":"356","year":"2010","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c25","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.ssnmr.2008.12.003","volume":"35","year":"2009","journal-title":"Solid State Nucl. Magn. Reson."},{"key":"2023062520492219500_c26","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1021\/ci960015+","volume":"36","year":"1996","journal-title":"Chem. Inf. Comput. Sci."},{"key":"2023062520492219500_c27","doi-asserted-by":"publisher","first-page":"2788","DOI":"10.1107\/S0567740882009960","volume":"38","year":"1982","journal-title":"Acta Crystallogr. Sect. B"},{"key":"2023062520492219500_c28","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1107\/S0365110X63001687","volume":"16","year":"1963","journal-title":"Acta Crystallogr."},{"key":"2023062520492219500_c29","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1107\/S0365110X63001109","volume":"16","year":"1963","journal-title":"Acta Crystallogr."},{"key":"2023062520492219500_c30","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1107\/S0365110X6100245X","volume":"14","year":"1961","journal-title":"Acta Crystallogr."},{"key":"2023062520492219500_c31","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1107\/S0567740868004747","volume":"24","year":"1968","journal-title":"Acta Crystallogr., Sect. B"},{"key":"2023062520492219500_c32","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.2138\/am.2007.2581","volume":"92","year":"2007","journal-title":"Am. Mineral."},{"key":"2023062520492219500_c33","doi-asserted-by":"publisher","first-page":"045107","DOI":"10.1103\/PhysRevB.81.045107","volume":"81","year":"2010","journal-title":"Phys. Rev. B"},{"key":"2023062520492219500_c34","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1524\/zkri.1994.209.7.616","volume":"209","year":"1994","journal-title":"Z. Kristallogr."},{"key":"2023062520492219500_c35","doi-asserted-by":"publisher","first-page":"115204","DOI":"10.1088\/0953-8984\/20\/11\/115204","volume":"20","year":"2008","journal-title":"J. Phys.: Condens. Matter"},{"key":"2023062520492219500_c36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0022-3093(99)00620-1","volume":"263","year":"2000","journal-title":"J. Non-Cryst. Solids"},{"key":"2023062520492219500_c37","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1038\/nmat1966","volume":"6","year":"2007","journal-title":"Nature Mater."},{"key":"2023062520492219500_c38","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1107\/S0108768110051050","volume":"67","year":"2011","journal-title":"Acta Crystallogr., Sect. B"},{"key":"2023062520492219500_c39","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1111\/j.1151-2916.1993.tb05316.x","volume":"76","year":"1993","journal-title":"J. Am. Ceram. Soc."},{"key":"2023062520492219500_c40","doi-asserted-by":"publisher","first-page":"3884","DOI":"10.1016\/j.jnoncrysol.2011.07.025","volume":"357","year":"2011","journal-title":"J. Non-Cryst. Solids."},{"key":"2023062520492219500_c41","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1016\/j.actbio.2010.11.037","volume":"7","year":"2011","journal-title":"Acta Biomater."},{"key":"2023062520492219500_c42","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.1016\/j.jnoncrysol.2011.05.031","volume":"357","year":"2011","journal-title":"J. Non-Cryst. Solids"}],"container-title":["The Journal of Chemical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/aip\/jcp\/article-pdf\/doi\/10.1063\/1.4774330\/15458366\/034501_1_online.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/aip\/jcp\/article-pdf\/doi\/10.1063\/1.4774330\/15458366\/034501_1_online.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T20:49:27Z","timestamp":1687726167000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/jcp\/article\/138\/3\/034501\/192463\/Structural-study-of-Al2O3-Na2O-CaO-P2O5-bioactive"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,15]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,1,21]]}},"URL":"https:\/\/doi.org\/10.1063\/1.4774330","relation":{},"ISSN":["0021-9606","1089-7690"],"issn-type":[{"value":"0021-9606","type":"print"},{"value":"1089-7690","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2013,1,21]]},"published":{"date-parts":[[2013,1,15]]},"article-number":"034501"}}