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The heating process is parametrically investigated to obtain an optimized condition in which a sterilization load is heated from 20 to 45\u2009\u00b0C within 2\u00a0min, and the forced convection is experimentally and numerically analyzed to find that the convection coefficient is dramatically increased to 450 W\/m2\u00a0K when compared with the conventional natural convection coefficient of 80 W\/m2\u00a0K. The optimized heating process is applied to a sterilization cycle using the impermeable pouch, and the overall sterilization cycle is found to be completed within 7.5\u00a0min whose performance is validated by using a process challenge device.<\/jats:p>","DOI":"10.1063\/5.0048688","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T10:01:24Z","timestamp":1623664884000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Forced convective heating for low-temperature sterilization"],"prefix":"10.1063","volume":"92","author":[{"given":"Seung Hun","family":"Lee","sequence":"first","affiliation":[{"name":"Plasmapp Co., Ltd. 1 , 372 Dongbu-daero, Osan-si, Gyeonggi-do 18151, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Jeong","family":"Jeon","sequence":"additional","affiliation":[{"name":"Plasmapp Co., Ltd. 1 , 372 Dongbu-daero, Osan-si, Gyeonggi-do 18151, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9923-8753","authenticated-orcid":false,"given":"Youbong","family":"Lim","sequence":"additional","affiliation":[{"name":"Plasmapp Co., Ltd. 1 , 372 Dongbu-daero, Osan-si, Gyeonggi-do 18151, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Plasmapp Co., Ltd. 1 , 372 Dongbu-daero, Osan-si, Gyeonggi-do 18151, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8952-8252","authenticated-orcid":false,"given":"Wonho","family":"Choe","sequence":"additional","affiliation":[{"name":"Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST) 2 , Daejeon 34141, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"317","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"issue":"2","key":"2023080502413009800_c1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1086\/647251","article-title":"Low-temperature sterilization technologies: Do we need to redefine `sterilization'","volume":"17","year":"1996","journal-title":"Infect. 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