{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:17:55Z","timestamp":1753874275280,"version":"3.41.2"},"reference-count":16,"publisher":"AIP Publishing","issue":"11","funder":[{"DOI":"10.13039\/501100003356","name":"Gazi \u00dcniversitesi","doi-asserted-by":"publisher","award":["FDK-2021-7017"],"award-info":[{"award-number":["FDK-2021-7017"]}],"id":[{"id":"10.13039\/501100003356","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:p>The aim of this study is to design\u00a0and test a new medical sterilization system as an alternative to the techniques used in the sterilization of medical instruments. The designed system, which uses a new oxygen molecule allotrope (NOMA) in the reactive oxygen species, is developed as an alternative to the sterilization systems using other gases. The test was conducted on 12 different materials, each having a surface of 2\u00a0cm2, sterilized under 120 \u00b0C at 1 atm pressure for 20\u00a0min\u00a0in the NUVE-OT 4060 sterilizer, and all surfaces were contaminated with a biological indicator Geobacillus stearothermophilus cultured in an incubator at 37 \u00b0C. Test samples in sterile Petri dishes were placed in a desiccator, and a sample was taken at 30-, 45-, and 60-min\u00a0test periods and were placed on an agar medium and put in a Memmert incubator IN75 at 37 \u00b0C; in the controls conducted following 16\u201318 h of incubation period, no bacterial growth was observed in the newly designed system tested with gram positive bacilli; moreover, it was observed that the new system was 100% effective in sterilizing the microbes as no growth was observed on the samples. Within the scope of this study, a faster, low-cost, low-temperature, residue-free, and human and environmental friendly system was developed and tested for sterilization of medical devices compared to existing sterilization methods using NOMA.<\/jats:p>","DOI":"10.1063\/5.0065104","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T13:34:46Z","timestamp":1637242486000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Designing and application of a new medical instrument sterilization system using reactive oxygen species"],"prefix":"10.1063","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6471-959X","authenticated-orcid":false,"given":"Hesna \u00d6zbek","family":"\u00dclk\u00fcta\u015f","sequence":"first","affiliation":[{"name":"Department of Advanced Technologies, Institute of Science and Technology, Gazi University 1 , 06500 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-1186","authenticated-orcid":false,"given":"Berrin","family":"\u00d6z\u00e7elik","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Gazi University 2 , 06560 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9064-5520","authenticated-orcid":false,"given":"\u0130nan","family":"G\u00fcler","sequence":"additional","affiliation":[{"name":"Department of Electrical and Electronic Engineering, Faculty of Technology, Gazi University 3 , 06560 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"317","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"issue":"2","key":"2023071604311949600_c1","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0927-7765(99)00144-7","article-title":"Instant water sterilizing system using active oxygen species","volume":"18","year":"2002","journal-title":"Colloids Surf., B"},{"key":"2023071604311949600_c2","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.procbio.2017.01.002","article-title":"Efficient sterilization using reactive oxygen species generated by a radical vapor reactor","volume":"54","year":"2017","journal-title":"Process Biochem."},{"issue":"3","key":"2023071604311949600_c3","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.bej.2010.06.017","article-title":"Sterilization of Streptococcus pyogenes by afterglow dielectric barrier discharge using O2 and CO2 working gases","volume":"51","year":"2010","journal-title":"Biochem. 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