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To assess the technique\u2019s safety and utility, we acquired microindentation measurements of bone material strength index (BMSi) using the OsteoProbe prior to distal radius fixation with a volar locking plate. Subsequently, the patients received a dual-energy x-ray absorptiometry scan to measure the areal bone mineral density of the proximal femur, lumbar spine, and contralateral distal radius. By assigning the patients to low-energy, fragility fracture (n = 17) and high-energy fracture (n = 11) groups based on clinical history, we investigated whether intraoperative BMSi was sensitive to osteoporosis. Impact microindentation added a maximum of 10\u00a0min\u00a0of operative time and did not result in any intraoperative or postoperative complications. There were, however, no significant differences in BMSi at the radius between these two groups. This study demonstrates the feasibility of performing intraoperative impact microindentation to directly assess a patient\u2019s bone quality, but additional research is necessary to establish whether intraoperative microindentation can identify patients with inferior bone matrix quality.<\/jats:p>","DOI":"10.1063\/5.0082751","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T12:24:18Z","timestamp":1654172658000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Intraoperative use of impact microindentation to assess distal radius bone quality"],"prefix":"10.1063","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6761-9188","authenticated-orcid":false,"given":"Donald H.","family":"Lee","sequence":"first","affiliation":[{"name":"Vanderbilt Orthopaedic Institute and the Department of Orthopaedic Surgery Hand and Upper Extremity Center, Vanderbilt University Medical Center, Medical Center East 1 , South Tower Suite 3200, 1215 21 st Avenue South, Nashville, Tennessee 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn","family":"Reasoner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Vanderbilt University Medical Center 2 , D-3100 Medical Center North, 1161 21 st Avenue South, Nashville, Tennessee 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasidhar","family":"Uppuganti","sequence":"additional","affiliation":[{"name":"Vanderbilt Orthopaedic Institute and the Department of Orthopaedic Surgery Hand and Upper Extremity Center, Vanderbilt University Medical Center, Medical Center East 1 , South Tower Suite 3200, 1215 21 st Avenue South, Nashville, Tennessee 37232, USA"},{"name":"Center of Bone Biology, Vanderbilt University Medical Center 3 , B-0213 Medical Center North, 1161 21 st Avenue South, Nashville, Tennessee 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir J.","family":"Desai","sequence":"additional","affiliation":[{"name":"Vanderbilt Orthopaedic Institute and the Department of Orthopaedic Surgery Hand and Upper Extremity Center, Vanderbilt University Medical Center, Medical Center East 1 , South Tower Suite 3200, 1215 21 st Avenue South, Nashville, Tennessee 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffry S.","family":"Nyman","sequence":"additional","affiliation":[{"name":"Vanderbilt Orthopaedic Institute and the Department of Orthopaedic Surgery Hand and Upper Extremity Center, Vanderbilt University Medical Center, Medical Center East 1 , South Tower Suite 3200, 1215 21 st Avenue South, Nashville, Tennessee 37232, USA"},{"name":"Center of Bone Biology, Vanderbilt University Medical Center 3 , B-0213 Medical Center North, 1161 21 st Avenue South, Nashville, Tennessee 37232, USA"},{"name":"Department of Biomedical Engineering, Vanderbilt University 4 , PMB 351631, 2301 Vanderbilt Place, Nashville, Tennessee 37232, USA"},{"name":"Department of Veterans Affairs, Tennessee Valley Healthcare System 5 , 1310 24 th Avenue South, Nashville, Tennessee 37212, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"317","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"2023081102224454300_c1","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/j.injury.2011.08.025","volume":"43","year":"2012","journal-title":"Injury"},{"key":"2023081102224454300_c2","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1302\/0301-620x.95b3.30514","volume":"95-B","year":"2013","journal-title":"Bone Joint J."},{"key":"2023081102224454300_c3","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.1007\/s11999-011-1838-6","volume":"469","year":"2011","journal-title":"Clin. 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