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In the present study, TTCF was used to evaluate the shear rate dependence of the slip length in a high-slip system consisting of water confined between graphene walls at experimentally accessible shear rates, for which classical nonequilibrium molecular dynamics (NEMD) is unfeasible. The corresponding Navier friction coefficient was computed for all shear rates spanning six orders of magnitude and compared with the equilibrium limit. We report for the first time NEMD results obtained at experimentally accessible shear rates using the TTCF approach for a system that has attracted significant interest over the past decades. The slip length calculated with TTCF is in good agreement with previous equilibrium molecular dynamics simulations and experiments. Our aim here is to highlight the extraordinary power of TTCF, particularly for high-slip (low effective shear rate) systems, and to verify that equilibrium methods directly match NEMD measurements at experimentally accessible shear rates.<\/jats:p>","DOI":"10.1063\/5.0334301","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T11:33:13Z","timestamp":1781695993000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Molecular dynamics simulation of high slip flow of water confined between graphene nanochannels at experimentally accessible shear rates"],"prefix":"10.1063","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1586-566X","authenticated-orcid":false,"given":"Carmelo Riccardo","family":"Civello","sequence":"first","affiliation":[{"name":"Department of Mathematics, Faculty of Science, Computing and Emerging Technologies, Swinburne University of Technology 1 , P.O. 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