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To overcome these challenges, we develop Traveling Wave Investigation Software Tool (TWIST), a numerical framework for the systematic computation of traveling wave solutions and their spectra. Using TWIST, we compute and compare dispersion relations in the FitzHugh\u2013Nagumo, Beeler\u2013Reuter, and nine-variable ten Tusscher\u2013Panfilov models. Our analysis shows that increasing physiological detail can introduce substantial additional structure in dispersion relations. In particular, the interaction of multiple activation processes in the ten Tusscher\u2013Panfilov model gives rise to additional solution branches, including families of slow waves that are absent in minimal models and may play important roles in abnormal wave dynamics. Our comparisons across models of increasing complexity distinguish robust features of wave propagation from those arising specifically from detailed ionic interactions and represent a step toward validating that the observed behaviors reflect genuine cardiac phenomena rather than artifacts of specific model formulations.<\/jats:p>","DOI":"10.1063\/5.0336554","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:04:15Z","timestamp":1790946255000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["A comparison of traveling wave properties in minimal and biophysically detailed models of cardiac tissue using a novel software tool"],"prefix":"10.1063","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3215-8996","authenticated-orcid":false,"given":"Vincent","family":"Lovero","sequence":"first","affiliation":[{"name":"Department of Mathematics, University of California 1 , Davis, California 95616,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3430-7234","authenticated-orcid":false,"given":"Stephanie","family":"Dodson","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Colby College 2 , Waterville, Maine 04901,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1885-746X","authenticated-orcid":false,"given":"Timothy J.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Mathematics, University of California 1 , Davis, California 95616,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"317","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"key":"2026100209040681700_c1","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/S0022-5193(89)80200-0","volume":"138","year":"1989","journal-title":"J. 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