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In this work, a technique based on a flow focusing technique is used to produce PDMS spherical particles with sizes of a few microns. PDMS precursor is injected through a hypodermic needle to form a film\/reservoir over the needle's outer surface. This film flows towards the needle tip until a liquid ligament is steadily ejected thanks to the action of a coflowing viscous liquid stream. The outcome is a capillary jet which breaks up into PDMS precursor droplets due to the growth of capillary waves producing a micrometer emulsion. The PDMS liquid droplets in the solution are thermally cured into solid microparticles. The size distribution of the particles is analyzed before and after curing, showing an acceptable degree of monodispersity. The PDMS liquid droplets suffer shrinkage while curing. These microparticles can be used in very varied technological fields, such as biomedicine, biotechnology, pharmacy, and industrial engineering.<\/jats:p>","DOI":"10.1063\/1.4943007","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T18:00:39Z","timestamp":1456423239000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":38,"title":["Generation of micro-sized PDMS particles by a flow focusing technique for biomicrofluidics applications"],"prefix":"10.1063","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6059-6913","authenticated-orcid":false,"given":"B. N.","family":"Mu\u00f1oz-S\u00e1nchez","sequence":"first","affiliation":[{"name":"Universidad de Sevilla 1 Depto. de Mec\u00e1nica de Fluidos e Ingenier\u00eda Aeroespacial, , E-41092 Sevilla, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8377-800X","authenticated-orcid":false,"given":"S. F.","family":"Silva","sequence":"additional","affiliation":[{"name":"Polytechnic Institute of Bragan\u00e7a 2 , Campus de Santa Apol\u00f3nia, Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3884-6496","authenticated-orcid":false,"given":"D.","family":"Pinho","sequence":"additional","affiliation":[{"name":"Polytechnic Institute of Bragan\u00e7a 2 , Campus de Santa Apol\u00f3nia, Bragan\u00e7a, Portugal"},{"name":"CEFT, FEUP 3 , R. Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"given":"E. J.","family":"Vega","sequence":"additional","affiliation":[{"name":"Universidad de Extremadura 4 Depto. de Ingenier\u00eda Mec\u00e1nica, Energ\u00e9tica y de los Materiales and Instituto de Computaci\u00f3n Cient\u00edfica Avanzada (ICCAEx), , E-06006 Badajoz, Spain"}]},{"given":"R.","family":"Lima","sequence":"additional","affiliation":[{"name":"CEFT, FEUP 3 , R. 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