{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:33:32Z","timestamp":1790710412158,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1067\/mhj.2001.112404","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T00:18:43Z","timestamp":1027556323000},"page":"190-199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":387,"title":["Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: A multinational registry of patients hospitalized with acute coronary syndromes"],"prefix":"10.1067","volume":"141","member":"78","reference":[{"key":"10.1067\/mhj.2001.112404_bib1","year":"1998"},{"key":"10.1067\/mhj.2001.112404_bib2","first-page":"227","article-title":"The World Heart Federation\u2019s white book: impending global pandemic of cardiovascular diseases: challenges and opportunities for the prevention and control of cardiovascular diseases in developing countries and economies in transition","volume":"16","author":"Chockalingam","year":"2000","journal-title":"Can J Cardiol"},{"key":"10.1067\/mhj.2001.112404_bib3","series-title":"2000 Heart and stroke statistical update","author":"American Heart Association","year":"1999"},{"key":"10.1067\/mhj.2001.112404_bib4","series-title":"Morbidity and mortality: 2000 chartbook on cardiovascular, lung, and blood diseases","author":"National Heart, Lung, and Blood Institute","year":"2000"},{"key":"10.1067\/mhj.2001.112404_bib5","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/oxfordjournals.eurheartj.a015434","article-title":"The burden of cardiovascular diseases mortality in Europe: Task Force of the European Society of Cardiology on cardiovascular mortality and morbidity statistics in Europe","volume":"18","author":"Sans","year":"1997","journal-title":"Eur Heart J"},{"key":"10.1067\/mhj.2001.112404_bib6","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1053\/euhj.1999.1983","article-title":"The ENACT study: a pan-European survey of acute coronary syndromes","volume":"21","author":"Fox","year":"2000","journal-title":"Eur Heart J"},{"key":"10.1067\/mhj.2001.112404_bib7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0895-4356(88)90084-4","article-title":"The World Health Organization MONICA Project (Monitoring Trends and Determinants in Cardiovascular Disease): a major international collaboration","volume":"41","author":"Tunstall-Pedoe","year":"1988","journal-title":"J Clin Epidemiol"},{"key":"10.1067\/mhj.2001.112404_bib8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0140-6736(99)04021-0","article-title":"Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA Project populations","volume":"353","author":"Tunstall\u2013Pedoe","year":"1999","journal-title":"Lancet"},{"key":"10.1067\/mhj.2001.112404_bib9","first-page":"134","article-title":"Cardiovascular disease mortality in the Americas","author":"Nicholls","year":"1993","journal-title":"World Health Stat Q"},{"key":"10.1067\/mhj.2001.112404_bib10","year":"1988"},{"issue":"2 Suppl","key":"10.1067\/mhj.2001.112404_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0140-6736(99)90233-7","article-title":"The challenge of acute coronary syndromes","volume":"353","author":"Simoons","year":"1999","journal-title":"Lancet"},{"key":"10.1067\/mhj.2001.112404_bib12","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1016\/S0735-1097(98)00473-2","article-title":"Clinical characteristics determining the mode of presentation in patients with acute coronary syndromes","volume":"32","author":"Kennon","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1067\/mhj.2001.112404_bib13","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0735-1097(98)00466-5","article-title":"Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb","volume":"32","author":"Alexander","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1067\/mhj.2001.112404_bib14","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1161\/01.CIR.98.11.1064","article-title":"Long-term oral anticoagulant therapy in patients with unstable angina or suspected non-Q-wave myocardial infarction: Organization to Assess Strategies for Ischemic Syndromes (OASIS) pilot study results","volume":"98","author":"Anand","year":"1998","journal-title":"Circulation"},{"key":"10.1067\/mhj.2001.112404_bib15","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1161\/01.CIR.97.12.1195","article-title":"Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction","volume":"97","author":"Theroux","year":"1998","journal-title":"Circulation"},{"key":"10.1067\/mhj.2001.112404_bib16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.0954-6820.1988.tb05549.x","article-title":"Problems with criteria and quality control in the registration of coronary events in the MONICA study","volume":"728","author":"Tunstall-Pedoe","year":"1988","journal-title":"Acta Med Scand Suppl"},{"key":"10.1067\/mhj.2001.112404_bib17","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1056\/NEJM199604043341403","article-title":"Recent trends in acute coronary heart disease\u2014mortality, morbidity, medical care, and risk factors","volume":"334","author":"McGovern","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1067\/mhj.2001.112404_bib18","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0002-8703(88)90876-9","article-title":"Incidence and case fatality rates of acute myocardial infarction (1975-1984): the Worcester Heart Attack Study","volume":"115","author":"Goldberg","year":"1988","journal-title":"Am Heart J"},{"key":"10.1067\/mhj.2001.112404_bib19","year":"1999"},{"key":"10.1067\/mhj.2001.112404_bib20","first-page":"923","article-title":"Comparison of outcomes research with clinical trials using preexisting data","volume":"84","author":"Canto","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1067\/mhj.2001.112404_bib21","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1053\/euhj.2000.2265","article-title":"Are data from clinical registries of any value?","volume":"21","author":"Alpert","year":"2000","journal-title":"Eur Heart J"},{"key":"10.1067\/mhj.2001.112404_bib22","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1053\/euhj.2000.2304","article-title":"National and regional registries: what good are they?","volume":"21","author":"Dyke","year":"2000","journal-title":"Eur Heart J"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870301536856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870301536856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T04:48:55Z","timestamp":1757566135000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870301536856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["S0002870301536856"],"URL":"https:\/\/doi.org\/10.1067\/mhj.2001.112404","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2001,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: A multinational registry of patients hospitalized with acute coronary syndromes","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1067\/mhj.2001.112404","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}