{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T19:17:29Z","timestamp":1715023049007},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1067\/mhj.2002.121808","type":"journal-article","created":{"date-parts":[[2002,10,9]],"date-time":"2002-10-09T21:24:11Z","timestamp":1034198651000},"page":"748-752","source":"Crossref","is-referenced-by-count":3,"title":["Enoxaparin in acute coronary syndromes: Evidence for superiority over placebo or untreated control"],"prefix":"10.1067","volume":"143","author":[{"given":"David","family":"Massel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moira K.","family":"Cruickshank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1067\/mhj.2002.121808_bib1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJM199201233260406","article-title":"The pathogenesis of coronary artery disease and the acute coronary syndromes","volume":"326","author":"Fuster","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1067\/mhj.2002.121808_bib2","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1161\/01.CIR.97.12.1195","article-title":"Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction","volume":"97","author":"Theroux","year":"1998","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/bmj.308.6921.81","article-title":"Collaborative overview of randomised trials of antiplatelet therapy I: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients","volume":"308","author":"Antiplatelet Trialists' Collaboration","year":"1994","journal-title":"Br Med J"},{"key":"10.1067\/mhj.2002.121808_bib4","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1001\/jama.1996.03540100055028","article-title":"Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients with unstable angina. A meta-analysis","volume":"276","author":"Oler","year":"1996","journal-title":"JAMA"},{"key":"10.1067\/mhj.2002.121808_bib5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"Dersimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1067\/mhj.2002.121808_bib6","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1016\/S0140-6736(00)02324-2","article-title":"Unfractionated heparin and low-molecular weight heparin in acute coronary syndrome without ST elevation: a meta-analysis","volume":"355","author":"Eikelboom","year":"2000","journal-title":"Lancet"},{"key":"10.1067\/mhj.2002.121808_bib7","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1056\/NEJM199709043371007","article-title":"Low-molecular-weight heparins","volume":"337","author":"Weitz","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1067\/mhj.2002.121808_bib8","doi-asserted-by":"crossref","first-page":"489S","DOI":"10.1378\/chest.114.5_Supplement.489S","article-title":"Heparin and low-molecular-weight heparin: mechanism of action, dosing, considerations, monitoring, efficacy, and safety","volume":"114","author":"Hirsh","year":"1998","journal-title":"Chest"},{"key":"10.1067\/mhj.2002.121808_bib9","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1161\/01.CIR.98.15.1575","article-title":"Low-molecular-weight heparin: a review of the results of recent studies of the treatment of venous thromboembolism and unstable angina","volume":"98","author":"Hirsh","year":"1998","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib10","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0735-1097(95)80001-W","article-title":"LMWH versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia","volume":"26","author":"Gurfinkel","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1067\/mhj.2002.121808_bib11","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0140-6736(96)91270-2","article-title":"Low-molecular-weight heparin during instability in coronary artery disease","volume":"347","author":"Fragmin during Instabiliry in Coronary Artery Disease FRISC study group","year":"1996","journal-title":"Lancet"},{"key":"10.1067\/mhj.2002.121808_bib12","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0140-6736(99)07350-X","article-title":"Long-term low-molecular-mass heparin in unstable coronary artery disease: FRISC II prospective randomised multicentre study","volume":"354","author":"Fragmin and fast revascularization during instability in coronary artery disease FRISC II investigators","year":"1999","journal-title":"Lancet"},{"key":"10.1067\/mhj.2002.121808_bib13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1161\/01.CIR.96.1.61","article-title":"Fragmin in unstable coronary artery disease study: comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease","volume":"96","author":"Klein","year":"1997","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib14","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1056\/NEJM199708143370702","article-title":"A comparison of low- molecular-weight heparin with UFH for unstable coronary artery disease: Efficacy and Safety of Subcutaneous enoxaparin in Non-Q-Wave Coronary Events Study Group","volume":"337","author":"Cohen","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1067\/mhj.2002.121808_bib15","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1161\/01.CIR.100.15.1593","article-title":"Enoxaparin prevents death and cardiac ischaemic events in unstable angina\/non-Q-wave myocardial infarction: results of the thrombolysis in myocardial infarction (TlMI) IIB trial","volume":"100","author":"Antman","year":"1999","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib16","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1053\/euhj.1999.1879","volume":"20","author":"The FRAXIS Study Group","year":"1999","journal-title":"Eur Heart J"},{"key":"10.1067\/mhj.2002.121808_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1067\/mhj.2001.111262","article-title":"Active-control trials: how would a new agent compare with placebo? A method illustrated with clopidogrel, aspirin, and placebo","volume":"141","author":"Fisher","year":"2000","journal-title":"Am Heart J"},{"key":"10.1067\/mhj.2002.121808_bib18","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0033-0620(85)80003-7","article-title":"Beta blockade during and after MI: an overview of the randomized trials","volume":"27","author":"Yusuf","year":"1985","journal-title":"Prog Cardiovascular Dis"},{"key":"10.1067\/mhj.2002.121808_bib19","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1056\/NEJM198810273191701","article-title":"Aspirin, heparin, or both to treat acute unstable angina","volume":"319","author":"Theroux","year":"1988","journal-title":"N Bngl J Med"},{"key":"10.1067\/mhj.2002.121808_bib20","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/0002-9149(90)91155-Y","article-title":"Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave myocardial infarction in preventing death and myocardial infarction (a pilot study from the Antithrombotic Therapy in Acute Coronary Syndromes Study Group)","volume":"66","author":"Cohen","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1067\/mhj.2002.121808_bib21","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0140-6736(90)92336-G","article-title":"Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease","volume":"336","author":"The RISC Group","year":"1990","journal-title":"Lancet"},{"key":"10.1067\/mhj.2002.121808_bib22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1161\/01.CIR.89.1.81","article-title":"Combination antithrombotic therapy in unstable rest angina and non-Q-wave infarction in nonprior aspirin users. Primary end points analysis from the ATACS trial","volume":"89","author":"Cohen","year":"1994","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib23","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0735-1097(94)90539-8","article-title":"Comparison of the effect of heparin and aspirin versus aspirin alone on transient myocardial ischemia and in-hospital prognosis in patients with unstable angina","volume":"24","author":"Holdright","year":"1994","journal-title":"J Am Coll Cardiol"},{"key":"10.1067\/mhj.2002.121808_bib24","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1161\/01.CIR.100.15.1602","article-title":"Assessment of the treatment effect of enoxaparin for unstable angina\/non-Q-wave myocardial infarction: TIMI11B-ESSENCE meta-analysis","volume":"100","author":"Antman","year":"1999","journal-title":"Circulation"},{"key":"10.1067\/mhj.2002.121808_bib25","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/j.0006-341X.1999.00484.x","article-title":"Bayesian design and analysis of active control clinical trials","volume":"55","author":"Simon","year":"1999","journal-title":"Biometrics"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870302404474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870302404474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T10:50:24Z","timestamp":1554720624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870302404474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S0002870302404474"],"URL":"https:\/\/doi.org\/10.1067\/mhj.2002.121808","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}