{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:03:43Z","timestamp":1789729423538,"version":"4.0.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2000,7]]},"abstract":"<jats:sec><jats:title>OBJECTIVES:<\/jats:title><jats:p>The goal of this study was to compare the outcome of patients with traumatic optic neuropathy (TON) treated with high\u2010dose steroids with the outcome of patients with TON treated with endoscopic optic nerve decompression (EOND) after failing high\u2010dose steroid treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>During this retrospective review of patients with TON seen from 1994 to 1998, all patients were first treated with megadose methylprednisolone for 48 hours. Patients with no improvement or with worsening visual acuity were offered EOND.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>Eleven of 34 (32%) patients treated with high\u2010dose steroids showed improvement, and 23 (68%) did not. Seventeen of the 23 patients without improvement after high\u2010dose steroid treatment underwent EOND. Fourteen of 17 (82%) surgically treated patients had improved visual acuity, and 3 (18%) did not, with an overall improvement in 25 of 34 (74%) patients (\u03c7<jats:sup>2<\/jats:sup> = 11.338, <jats:italic>P<\/jats:italic> = 0.0007).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION:<\/jats:title><jats:p>EOND is an appropriate treatment technique for patients with TON in whom high\u2010dose steroid treatment has failed. (Otolaryngol Head Neck Surg 2000;123:34\u20107.)<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2000.106007","type":"journal-article","created":{"date-parts":[[2003,2,4]],"date-time":"2003-02-04T21:49:09Z","timestamp":1044395349000},"page":"34-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Endoscopic Optic Nerve Decompression for Traumatic Blindness"],"prefix":"10.1002","volume":"123","author":[{"given":"Stilianos E.","family":"Kountakis","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Virginia Medical School Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto A. J.","family":"Maillard","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif M.","family":"El\u2010Harazi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Science University of Texas\u2010Houston Medical School Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Longhini","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Science University of Texas\u2010Houston Medical School Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard G.","family":"Urso","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Science University of Texas\u2010Houston Medical School Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2000,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198102000-00002"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(82)34769-7"},{"issue":"2","key":"e_1_2_1_4_1","first-page":"102","article-title":"Traumatic optic neuropathy: Analysis of 37 cases [abstract]","volume":"27","author":"Tang RA","year":"1986","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1989.01070010392031"},{"key":"e_1_2_1_6_1","first-page":"389","article-title":"High dose corticosteroids for treatment of vision loss due to indirect injury to the optic nerve","volume":"21","author":"Seiff SR","year":"1990","journal-title":"Ophthalmic Surg"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(61)91611-7"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1976.03910030534017"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-1810(10)80050-8"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1979.50.1.0031"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(95)90082-9"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70243-2"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2000.106007","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1067\/mhn.2000.106007","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2000.106007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:30:49Z","timestamp":1760970649000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2000.106007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["10.1067\/mhn.2000.106007"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2000.106007","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]},"assertion":[{"value":"2000-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}