{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:43:35Z","timestamp":1761007415823,"version":"build-2065373602"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":5814,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2000,10]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Technetium Tc 99m sestamibi scan is the standard of care for localizing parathyroid adenomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS AND MATERIAL<\/jats:title><jats:p>We performed a retrospective, single\u2010institution study of 111 consecutive patients with primary hyperparathyroidism who underwent standard sestamibi scan for localization of a parathyroid lesion. A revised protocol of reduced\u2010time\u2010window sestamibi scan was used in nonlocalized patients. The protocol was composed of single\u2010view scans at 15, 30, 45, and 120\u00a0minutes and tomograms at 60\u00a0minutes.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Thirty\u2010five patients underwent surgery at our institution. Thirty\u2010one had adenomas, and 4 had hyperplasia. Three of 31 patients did not show localization on the standard scan and underwent reduced\u2010time\u2010window scans, which localized 2\u00a0more adenomas. These were confirmed at the time of surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>We suggest that all patients with a high degree of suspicion for a parathyroid adenoma, which is not visualized by a standard scan, undergo a reduced\u2010time\u2010window scan.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2000.109017","type":"journal-article","created":{"date-parts":[[2003,2,4]],"date-time":"2003-02-04T21:49:09Z","timestamp":1044395349000},"page":"456-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Reduced\u2010Time\u2010Window Sestamibi Scanning for Nonlocalized Primary Hyperparathyroidism"],"prefix":"10.1002","volume":"123","author":[{"given":"Ashutosh","family":"Kacker","sequence":"first","affiliation":[{"name":"Departments of Otorhinolaryngology Lenox Hill Hospital New York New York"},{"name":"Departments of Nuclear Medicine Lenox Hill Hospital New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Scharf","sequence":"additional","affiliation":[{"name":"Departments of Otorhinolaryngology Lenox Hill Hospital New York New York"},{"name":"Departments of Nuclear Medicine Lenox Hill Hospital New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnold","family":"Komisar","sequence":"additional","affiliation":[{"name":"Departments of Otorhinolaryngology Lenox Hill Hospital New York New York"},{"name":"Departments of Nuclear Medicine Lenox Hill Hospital New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"681","article-title":"Parathyroid imaging","volume":"29","author":"Petti GH","year":"1996","journal-title":"Otolaryngol Clin North Am"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430140106026"},{"key":"e_1_2_6_4_2","first-page":"582","article-title":"Cost effectiveness of preoperative localization studies in primary hyperparathyroid disease","volume":"219","author":"Roe S","year":"1994","journal-title":"Ann Surg"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890160011002"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556139607500713"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199805000-00001"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.6.649"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(98)00016-7"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/02841851960373P260"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199702000-00001"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2000.109017","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1067\/mhn.2000.109017","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2000.109017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:13:11Z","timestamp":1760965991000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2000.109017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["10.1067\/mhn.2000.109017"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2000.109017","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2000,10]]},"assertion":[{"value":"2016-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}