{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:44:03Z","timestamp":1777506243136,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":5541,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To determine the effect of nasal irrigation on sinonasal symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>A total of 150 adult subjects with chronic sinusitis symptoms were recruited from the community and assigned to 1 of 3 treatment groups: nasal irrigation with bulb syringe, nasal irrigation with nasal irrigation pot, or control treatment with reflexology massage. Groups 1 and 2 performed daily hypertonic saline irrigation with 1 device for 2 weeks and then with the other device for 2 weeks. Group 3 performed reflexology massage daily for 2 weeks. Prospective data collected included pretreatment Medical Outcomes Study Short Form, pretreatment and posttreatment Rhinosinusitis Outcomes Measure, daily medication use, subjective treatment efficacy, and preference of irrigation method.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>There was a significant and equivalent improvement in Rhinosinusitis Outcomes Measure 31 score after 2 weeks of intervention in each treatment group; 35% of subjects reported decreased use of sinus medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Daily nasal irrigation using either a bulb syringe, nasal irrigation pot, and daily reflexology massage were equally efficacious and resulted in improvement in the symptoms of chronic sinusitis in over 70% of subjects. Medication usage was decreased in approximately one third of participants regardless of intervention.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2001.115909","type":"journal-article","created":{"date-parts":[[2003,2,4]],"date-time":"2003-02-04T21:49:09Z","timestamp":1044395349000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":131,"title":["Nasal Irrigation for the Alleviation of Sinonasal Symptoms"],"prefix":"10.1002","volume":"125","author":[{"given":"Diane G.","family":"Heatley","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery Department of Surgery University of Wisconsin School of Medicine Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kari E.","family":"McConnell","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery Department of Surgery University of Wisconsin School of Medicine Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony L.","family":"Kille","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery Department of Surgery University of Wisconsin School of Medicine Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glen E.","family":"Leverson","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Department of Surgery University of Wisconsin School of Medicine Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Annual expenses and sources of payment for health care services.","author":"Hahn B","year":"1994"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(97)80037-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200007000-00023"},{"key":"e_1_2_6_5_1","first-page":"29","article-title":"Nasal douching as a valuable adjunct in the management of chronic rhinosinusitis","volume":"37","author":"Taccariello M","year":"1999","journal-title":"Rhinology"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70166-6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.7.1.39"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065895781808711"},{"key":"e_1_2_6_10_1","volume-title":"Stories the feet have told.","author":"Ingham ED","year":"1982"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90173-Y"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199704000-00013"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199908000-00007"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2001.115909","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1067\/mhn.2001.115909","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2001.115909","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:41:03Z","timestamp":1760971263000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2001.115909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["10.1067\/mhn.2001.115909"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2001.115909","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,7]]},"assertion":[{"value":"2016-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}