{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:11:59Z","timestamp":1790187119650,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":5418,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2001,11]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>Pilomatrixomas are benign skin neoplasms of hair follicle origin. They are one of the most common superficial masses of the head and neck excised in children. Although the entity has been well studied in the literature, few studies have been undertaken to evaluate the clinical characteristics of head and neck pilomatrixomas specifically in children. The purpose of this study was to review the clinical characteristics and management of children presenting with pilomatrixomas of the head and neck at a large tertiary care pediatric hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN<\/jats:title><jats:p>A retrospective chart review was performed of all patients with histologically confirmed pilomatrixoma of the head and neck excised during a 6\u2010year period (1992\u20131997) at the Children's Hospital of Philadelphia.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Ninety\u2010one cases of pilomatrixoma were confirmed in 86 patients. The age range was 5\u00a0months to 17 years. The median age at time of excision was 6.0 years. The most common sites of occurrence were the cheek (36%), neck (20%), periorbital region (14%), and scalp (9%). The male to female ratio was 1:1.5. Multiple lesions were found in 8.2% of patients. Surgical excision was curative in all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Pilomatrixoma is a cutaneous neoplasm that is one of most common causes of superficial head and neck masses in children. Although the presurgical diagnosis may be difficult in some cases, pilomatrixoma must be kept in the differential of superficial head and neck masses in children. Surgical excision is almost always curative.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2001.117371","type":"journal-article","created":{"date-parts":[[2003,2,4]],"date-time":"2003-02-04T21:49:09Z","timestamp":1044395349000},"page":"510-515","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Pilomatrixoma of the Head and Neck in Children"],"prefix":"10.1002","volume":"125","author":[{"given":"Ravi P.","family":"Agarwal","sequence":"first","affiliation":[{"name":"Division of Pediatric Otolaryngology The Children's Hospital of Philadelphia Philadelphia Pennsylvania"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery University of Pennsylvania School of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Handler","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology The Children's Hospital of Philadelphia Philadelphia Pennsylvania"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery University of Pennsylvania School of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Matthews","sequence":"additional","affiliation":[{"name":"Department of Pathology The Children's Hospital of Philadelphia Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Carpentieri","sequence":"additional","affiliation":[{"name":"Department of Pathology The Children's Hospital of Philadelphia Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_14_2_1","first-page":"826","article-title":"Note sur l'epitheliome calcifie des glandes sebacees","volume":"8","author":"Malherbe A","year":"1880","journal-title":"Prog Med"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1961.01580100070009"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1973.01620250020004"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.72.2.147"},{"key":"e_1_2_14_6_1","first-page":"483","article-title":"Pilomatrixoma: A common, benign childhood skin tumor","volume":"37","author":"Wells NJ","year":"1994","journal-title":"Can J Surg"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00174442"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.11.1239"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1981.tb04911.x"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)70071-X"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1972.01620100029008"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000018286"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/123.1.151"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949710600214"},{"key":"e_1_2_14_15_1","first-page":"22","volume-title":"Pathology of the skin with clinical correlations","author":"McKee PH","year":"1996"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930415)71:8<2491::AID-CNCR2820710811>3.0.CO;2-I"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb01669.x"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960401)77:7<1311::AID-CNCR13>3.0.CO;2-4"},{"key":"e_1_2_14_19_1","first-page":"847","article-title":"Fine needle aspiration cytology of pilomatrixoma (calcifying epilthelioma of Malherbe)","volume":"34","author":"Unger P","year":"1990","journal-title":"Acta Cytol"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890070114"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1976.00780170071012"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(80)80291-X"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2001.117371","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1067\/mhn.2001.117371","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2001.117371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:15:33Z","timestamp":1760962533000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2001.117371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["10.1067\/mhn.2001.117371"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2001.117371","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,11]]},"assertion":[{"value":"2016-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}