{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:20:44Z","timestamp":1792059644650,"version":"4.4.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":5114,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The study goal was to demonstrate that blink reflex analysis can predict postoperative facial nerve outcome in cerebellopontine angle tumor surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN, SETTING, AND PATIENTS<\/jats:title><jats:p>In an open and prospective study conducted at a single tertiary care center over 3 years, 91 subjects with a vestibular schwannoma filling the internal auditory meatus were enrolled and operated on via a translabyrinthine approach. The difference in latency of the early response (\u03b4R1) of the blink reflex between the pathologic side and the healthy side was calculated in every patient during a complete electrophysiologic examination of the facial nerve performed on the day before surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>MAIN OUTCOME MEASURES<\/jats:title><jats:p>\u03b4R1 was compared with the other preoperative data (tumor volume, facial function), with the perioperative observations (difficulties with the dissection of the facial nerve), and especially with the postoperative status after 1 year. The statistical study was conducted using polynomial regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Patients with a negative or zero \u03b4R1 have normal facial function at 1 year. For those with a positive \u03b4R1 the outcome is not favorable unless the tumor is small. For patients presenting with an immediate complete facial paralysis, the value of \u03b4R1 is also indicative of facial function outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Statistical analysis shows that the blink reflex, through \u03b4R1, has an excellent prognostic value in anticipating the difficulties with facial nerve dissection and postoperative facial function after 1 year.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2002.127606","type":"journal-article","created":{"date-parts":[[2003,2,4]],"date-time":"2003-02-04T21:49:09Z","timestamp":1044395349000},"page":"153-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Prognostic Value of the Blink Reflex in Acoustic Neuroma Surgery"],"prefix":"10.1002","volume":"127","author":[{"given":"Vincent","family":"Darrouzet","sequence":"first","affiliation":[{"name":"Department of Skull Base Surgery University Hospital of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Hilton","sequence":"additional","affiliation":[{"name":"University Department of Otolaryngology Southmead Hospital Bristol United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Pinder","sequence":"additional","affiliation":[{"name":"University Department of Otolaryngology St Michael's Hospital Bristol United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jio\u2010Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"University Department of Otolaryngology Rui Jin Hospital Shangai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Guerin","sequence":"additional","affiliation":[{"name":"Department of Skull Base Surgery University Hospital of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Pierre","family":"Bebear","sequence":"additional","affiliation":[{"name":"Department of Skull Base Surgery University Hospital of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"437","article-title":"Preservation of the functions of facial and cochlear nerves after excision of acoustic neurinoma","volume":"109","author":"Portmann M","year":"1988","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"e_1_2_6_3_1","first-page":"487","article-title":"Surgery of acoustic neuroma and other tumors of the internal auditory canal and cerebellopontile angle. Apropos of 602 cases","volume":"103","author":"Sterkers JM","year":"1986","journal-title":"Ann Otolaryngol Chir Cervicofac"},{"key":"e_1_2_6_4_1","first-page":"119","article-title":"Presurgical electrophysiological findings in acoustic nerve tumors","volume":"32","author":"Pavesi G","year":"1992","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170209"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988709700302"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00306812"},{"key":"e_1_2_6_8_1","first-page":"1117","article-title":"Evaluation of blink reflexes in cerebellopontine angle tumors","volume":"35","author":"Nagahiro S","year":"1983","journal-title":"No To Shinkei"},{"key":"e_1_2_6_9_1","first-page":"201","article-title":"Blink reflex and jaw reflex in neurinoma of the acoustic and trigeminal nerves (author's transl)","volume":"80","author":"Gil R","year":"1980","journal-title":"Acta Neurol Belg"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0370-4475(78)80004-5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880171209"},{"key":"e_1_2_6_12_1","volume-title":"Electrodiagnosis in Disease of Nerve and Muscle: Principles and Practice","author":"Kimura J","year":"1983"},{"key":"e_1_2_6_13_1","first-page":"497","volume-title":"Long\u2010Term Results and Indications in Otology and Otoneurosurgery","author":"Bebear J","year":"1990"},{"key":"e_1_2_6_14_1","volume-title":"Valeur Pronostique de l'Electrophisologie Pre\u2010operatoire du Nerf Facial Dans la Chirurgie du Neurinome de l'Acoustique","author":"Daverat F","year":"1989"},{"key":"e_1_2_6_15_1","first-page":"139","volume-title":"Le Neurinome de l'Acoustique et la Pathologie Chirurgicale de l'angle Ponto\u2010Cerebelleux","author":"Portmann M","year":"1982"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300202"},{"key":"e_1_2_6_17_1","first-page":"27","article-title":"The blink reflex as a diagnostic procedure","volume":"50","author":"Bender LF","year":"1969","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770080188002"},{"key":"e_1_2_6_19_1","unstructured":"SterkersJ.Complications: Prevention et traitement. 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