{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:25:35Z","timestamp":1784003135742,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T00:00:00Z","timestamp":1482192000000},"content-version":"vor","delay-in-days":5043,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>We evaluated changes in disease\u2010specific quality of life (QOL) for children with sleep\u2010disordered breathing (SDB).<\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS, DESIGN, AND SETTING<\/jats:title><jats:p>We conducted a cohort study in 69 children (age range, 6\u00a0months to 13 years; median age, 6.1 years) from a hospital\u2010based pediatric otolaryngology practice in a metropolitan area. We used the OSA\u201018, an 18\u2010item QOL survey with known test\u2010retest reliability, internal consistency, and construct validity. Survey domains included sleep disturbance, physical suffering, emotional distress, daytime problems, and caregiver concerns.<\/jats:p><\/jats:sec><jats:sec><jats:title>INTERVENTION<\/jats:title><jats:p>Tonsillectomy or adenoidectomy was performed as part of routine clinical care. The OSA\u201018 was completed at entry by the child's caregiver and again at least 4 weeks after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>MAIN OUTCOME MEASURES<\/jats:title><jats:p>The validity of the OSA\u201018 change score was assessed by comparison with multiple external constructs, including a validated measure of longitudinal change (OSD\u20106 survey). Responsiveness was assessed by the standardized response mean (SRM).<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The mean baseline OSA\u201018 survey score was 3.1 (SD, 0.9) of a maximum 7.0, with higher values indicating poorer QOL. Change scores were available for all children, with a mean interval between preoperative and postoperative surveys of 61\u00a0days (range, 42 to 92\u00a0days). The mean OSA\u201018 change score of 1.14 (SD, 0.71) showed significant correlation with tonsil size (<jats:italic>r<\/jats:italic> = 0.40), adenoid size (<jats:italic>r<\/jats:italic> = 0.31), OSD\u20106 change scores (<jats:italic>r<\/jats:italic> = 0.71), and the direct caregiver estimates of change (<jats:italic>r<\/jats:italic> = 0.34). OSA\u201018 change scores showed large responsiveness to change (SRM 1.44; 95% confidence interval, 1.16 to 69), with the most responsive domains being sleep disturbance, physical suffering, and care\u2010giver concerns. Significant responsiveness was also demonstrated for the domains of daytime problems and emotional distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The OSA\u201018 is a valid, reliable, and responsive QOL measure that combines the advantages of a discriminative and evaluative survey in a single instrument. The OSA\u201018 is a useful measure of patient\u2010based outcomes for clinical trials, health services research, and routine clinical care.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2003.4","type":"journal-article","created":{"date-parts":[[2003,3,25]],"date-time":"2003-03-25T21:25:50Z","timestamp":1048627550000},"page":"344-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Evaluation of Sleep\u2010Disordered Breathing in Children"],"prefix":"10.1002","volume":"128","author":[{"given":"Han","family":"Sohn","sequence":"first","affiliation":[{"name":"Department of Otolaryngology State University of New York Downstate Medical Center and The Long Island College Hospital Brooklyn New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Rosenfeld","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology State University of New York Downstate Medical Center and The Long Island College Hospital Brooklyn New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.3.616"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.5.1178"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.3.610"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900305"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.12.1423"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.105254"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.1.45"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.5.585"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90069-5"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80348-0"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)36806-7"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(94)90036-1"},{"key":"e_1_2_5_14_1","volume-title":"Health measurement scales: a practical guide to their development and use","author":"Streiner DL","year":"1995"},{"key":"e_1_2_5_15_1","volume-title":"True Epistat reference manual, 5th ed","author":"Gustafson TL","year":"1994"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-118-8-199304150-00009"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200003002-00004"},{"key":"e_1_2_5_18_1","first-page":"375","volume-title":"Evidence\u2010based otitis media","author":"Haggard MP","year":"1999"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199007000-00008"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(05)80019-4"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2003.4","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1067\/mhn.2003.4","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2003.4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:53:13Z","timestamp":1760953993000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2003.4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,3]]}},"alternative-id":["10.1067\/mhn.2003.4"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2003.4","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,3]]},"assertion":[{"value":"2016-12-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}