{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:36:09Z","timestamp":1787668569836,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":4961,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The first objective of this study was to evaluate pain intensity and opioid consumption during the first 24 hours after uvulopalatoplasty and tonsillectomy in the hospital, and the second was to evaluate pain intensity and its progression during the first 2 weeks after surgery at home.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTINGS<\/jats:title><jats:p>In a prospective parallel group study, 51 patients with uvulopalatoplasty or tonsillectomy were studied. Ketoprofen, a nonsteroidal antiinflammatory drug, and fentanyl citrate, an opioid, were used as analgesics.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Despite ketoprofen infusion and free access to a patient\u2010controlled pump with fentanyl citrate for rescue analgesia, inadequate pain relief was common both after uvulopalatoplasty (35%) and after tonsillectomy (28%) during the first 24 hours after surgery. The consumption of fentanyl citrate was similar after both operations. At home, pain intensity was highest in the mornings during the first 5\u00a0days, and 10 patients had some pain still after 2 weeks. Also at home, high pain scores were reported commonly in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Sgnificant pain after uvulopalatoplasty and tonsillectomy lasted for several days. Ketoprofen in the commercial capsule form proved to be too short acting for overnight pain relief.<\/jats:p><\/jats:sec><jats:sec><jats:title>SIGNIFICANCE<\/jats:title><jats:p>Pain treatment in patients with uvulopalatoplasty and tonsillectomy should be improved to allow patients a peaceful recovery after surgery.<\/jats:p><\/jats:sec>","DOI":"10.1067\/mhn.2003.82","type":"journal-article","created":{"date-parts":[[2003,3,4]],"date-time":"2003-03-04T13:28:22Z","timestamp":1046784502000},"page":"273-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Pain Intensity after Laseruvulopalatoplasty and Tonsillectomy"],"prefix":"10.1002","volume":"128","author":[{"given":"Hannu","family":"Kokki","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Kuopio University Hospital Department of Otorhinolaryngology Central Hospital of Central Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elina","family":"Nikanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko","family":"Aho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Kuopio University Hospital Department of Otorhinolaryngology Central Hospital of Central Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukka","family":"Virtaniemi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Kuopio University Hospital Department of Otorhinolaryngology Central Hospital of Central Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_14_2_1","first-page":"171","volume-title":"Snoring and obstructive sleep apnoea","author":"Colman MF","year":"1987"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/66.6.703"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00203-9"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199708000-00028"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1997.tb04657.x"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(97)00202-9"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199912000-00010"},{"key":"e_1_2_14_9_1","unstructured":"World Medical Association Declaration of Helsinki.Ethical Principles for Medical Research Involving Human Subjects. 52nd World Medical Association General Assembly Edinburgh Scotland October2000."},{"key":"e_1_2_14_10_1","volume-title":"Guidelines for ATC classification and DDD assignment","year":"2000"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1994.tb03979.x"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/81.3.369"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03011774"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100143087"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000604"},{"key":"e_1_2_14_16_1","first-page":"155","article-title":"One\u2010stage laser\u2010assisted uvulopalatoplasty","volume":"25","author":"Dickson RI","year":"1996","journal-title":"J Otol"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/cp.1999.v66.a101063"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2003.82","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1067\/mhn.2003.82","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1067\/mhn.2003.82","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:12:13Z","timestamp":1760965933000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1067\/mhn.2003.82"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["10.1067\/mhn.2003.82"],"URL":"https:\/\/doi.org\/10.1067\/mhn.2003.82","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,2]]},"assertion":[{"value":"2016-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}