{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:06:55Z","timestamp":1783350415052,"version":"3.54.6"},"reference-count":13,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1067\/mjd.2001.112219","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T04:18:43Z","timestamp":1027570723000},"page":"298-299","source":"Crossref","is-referenced-by-count":62,"special_numbering":"P1","title":["Recurrent erythema nodosum associated with echinacea herbal therapy"],"prefix":"10.1067","volume":"44","author":[{"given":"Seaver","family":"Lee Soon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard I.","family":"Crawford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/mjd.2001.112219_bib1","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1001\/jama.280.18.1569","article-title":"Trends in alternative medicine use in the United States","volume":"280","author":"Eisenberg","year":"1998","journal-title":"JAMA"},{"key":"10.1067\/mjd.2001.112219_bib2","series-title":"A treatise on echinacea","author":"Lloyd","year":"1924"},{"key":"10.1067\/mjd.2001.112219_bib3","series-title":"Herbal medicine: a guide for health care professionals","author":"Newall","year":"1996"},{"key":"10.1067\/mjd.2001.112219_bib4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0002-9343(98)00406-9","article-title":"A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections","volume":"106","author":"Grimm","year":"1999","journal-title":"Am J Med"},{"key":"10.1067\/mjd.2001.112219_bib5","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0162-3109(96)00125-7","article-title":"In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients","volume":"35","author":"See","year":"1997","journal-title":"Immunopharmacology"},{"key":"10.1067\/mjd.2001.112219_bib6","first-page":"276","article-title":"Immunologic in vivo and in vitro studies on Echinacea extracts","volume":"38","author":"Bauer","year":"1988","journal-title":"Arzneimittel-forschung"},{"key":"10.1067\/mjd.2001.112219_bib7","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/0192-0561(91)90046-A","article-title":"Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to test subjects mediates activation of the phagocyte system","volume":"13","author":"Roesler","year":"1991","journal-title":"Int J Immunopharmacol"},{"key":"10.1067\/mjd.2001.112219_bib8","first-page":"1076","article-title":"Toxicity of Echinacea purpurea","volume":"41","author":"Mengs","year":"1991","journal-title":"Arzneimettelforschung"},{"key":"10.1067\/mjd.2001.112219_bib9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.5694\/j.1326-5377.1998.tb126773.x","article-title":"Echinacea-associated anaphylaxis","volume":"168","author":"Mullins","year":"1998","journal-title":"Med J Aust"},{"key":"10.1067\/mjd.2001.112219_bib10","series-title":"Herb contraindications and drug interactions","author":"Brinker","year":"1998"},{"key":"10.1067\/mjd.2001.112219_bib11","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/iai.46.3.845-849.1984","article-title":"Macrophage activation and induction of macropage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea","volume":"46","author":"Stimpel","year":"1984","journal-title":"Infect Immun"},{"key":"10.1067\/mjd.2001.112219_bib12","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/0192-0561(93)90078-D","article-title":"Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes","volume":"15","author":"Steinmuller","year":"1993","journal-title":"Int J Immunopharmacol"},{"key":"10.1067\/mjd.2001.112219_bib13","year":"1999"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962201570899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962201570899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T15:02:56Z","timestamp":1680534176000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962201570899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["S0190962201570899"],"URL":"https:\/\/doi.org\/10.1067\/mjd.2001.112219","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}