{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:48:55Z","timestamp":1791384535341,"version":"4.3.3"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2003,2]]},"DOI":"10.1067\/mjd.2003.69","type":"journal-article","created":{"date-parts":[[2003,2,11]],"date-time":"2003-02-11T23:37:03Z","timestamp":1045006623000},"page":"207-214","source":"Crossref","is-referenced-by-count":46,"title":["Organotypic cultures of autologous hair follicle keratinocytes for the treatment of recurrent leg ulcers"],"prefix":"10.1067","volume":"48","author":[{"given":"Alain","family":"Limat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars E.","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Blal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Hilaire","family":"Saurat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hunziker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Salomon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/mjd.2003.69_bib1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1080\/02813430050202587","article-title":"Prevalence of non healed and healed chronic leg ulcers in an elderly rural population","volume":"18","author":"Marklund","year":"2000","journal-title":"Scand J Prim Health Care"},{"key":"10.1067\/mjd.2003.69_bib2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0733-8635(05)70414-9","article-title":"What is new in clinical research in wound healing","volume":"15","author":"Choucair","year":"1997","journal-title":"Dermatol Clin"},{"key":"10.1067\/mjd.2003.69_bib3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1159\/000060608","article-title":"Therapy with growth factors","volume":"27","author":"Limat","year":"1999","journal-title":"Curr Probl Dermatol"},{"key":"10.1067\/mjd.2003.69_bib4","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1365-2133.1987.tb07491.x","article-title":"Treatment of chronic venous ulcers with sheets of cultured allogeneic keratinocytes","volume":"117","author":"Leigh","year":"1987","journal-title":"Br J Dermatol"},{"key":"10.1067\/mjd.2003.69_bib5","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2133.1990.tb08243.x","article-title":"Fresh versus cryopreserved cultured allografts for the treatment of chronic skin ulcers","volume":"122","author":"Teepe","year":"1990","journal-title":"Br J Dermatol"},{"key":"10.1067\/mjd.2003.69_bib6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0002-9610(99)80258-X","article-title":"Transplantation of keratinocytes in the treatment of wounds","volume":"170","author":"Myers","year":"1995","journal-title":"Am J Surg"},{"key":"10.1067\/mjd.2003.69_bib7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1001\/archderm.134.3.293","article-title":"Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent","volume":"134","author":"Falanga","year":"1998","journal-title":"Arch Dermatol"},{"key":"10.1067\/mjd.2003.69_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000060609","article-title":"Cultured keratinocyte grafts","volume":"27","author":"Hunziker","year":"1999","journal-title":"Curr Probl Dermatol"},{"key":"10.1067\/mjd.2003.69_bib9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0733-8635(05)70199-6","article-title":"Skin grafting","volume":"18","author":"Valencia","year":"2000","journal-title":"Dermatol Clin"},{"key":"10.1067\/mjd.2003.69_bib10","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1159\/000060645","article-title":"Surgical management of varicose veins in advanced chronic venous insufficiency","volume":"27","author":"Cassina","year":"1999","journal-title":"Curr Probl Dermatol"},{"key":"10.1067\/mjd.2003.69_bib11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000060648","article-title":"Shave therapy for recalcitrant venous ulcers","volume":"27","author":"Schmeller","year":"1999","journal-title":"Curr Probl Dermatol"},{"key":"10.1067\/mjd.2003.69_bib12","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(75)80001-8","article-title":"Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells","volume":"6","author":"Rheinwald","year":"1975","journal-title":"Cell"},{"key":"10.1067\/mjd.2003.69_bib13","first-page":"116","article-title":"Human keratinocytes cultured on membranes composed of benzyl ester of hyaluronic acid suitable for grafting","volume":"3","author":"Andreassi","year":"1991","journal-title":"Wounds"},{"key":"10.1067\/mjd.2003.69_bib14","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/0092-8674(94)90383-2","article-title":"Location of stem cells of human hair follicles by clonal analysis","volume":"76","author":"Rochat","year":"1994","journal-title":"Cell"},{"key":"10.1067\/mjd.2003.69_bib15","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/1523-1747.ep12312406","article-title":"Proliferative potential of different keratinocytes of plucked human hair follicles","volume":"105","author":"Moll","year":"1995","journal-title":"J Invest Dermatol"},{"key":"10.1067\/mjd.2003.69_bib16","first-page":"21","article-title":"Cultivation of keratinocytes from the outer root sheath of human hair follicles","author":"Limat","year":"1996"},{"key":"10.1067\/mjd.2003.69_bib17","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0014-4827(91)90357-Z","article-title":"Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts","volume":"194","author":"Limat","year":"1991","journal-title":"Exp Cell Res"},{"key":"10.1067\/mjd.2003.69_bib18","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1097\/00007890-199504150-00020","article-title":"Formation of a regular neo-epidermis by cultured human outer root sheath cells grafted on nude mice","volume":"59","author":"Limat","year":"1995","journal-title":"Transplantation"},{"key":"10.1067\/mjd.2003.69_bib19","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0092-8674(01)00208-2","article-title":"Morphogenesis and renewal of hair follicles from adult multipotent stem cells","volume":"104","author":"Oshima","year":"2001","journal-title":"Cell"},{"key":"10.1067\/mjd.2003.69_bib20","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/jid.1955.112","article-title":"Responses of the superficial portion of the human pilosebaceous apparatus to controlled injury","volume":"15","author":"Eisen","year":"1955","journal-title":"J Invest Dermatol"},{"key":"10.1067\/mjd.2003.69_bib21","first-page":"324","article-title":"Kinetics of epidermal production during epidermal regeneration following abrasion in mice","volume":"83","author":"Argyris","year":"1976","journal-title":"Am J Pathol"},{"key":"10.1067\/mjd.2003.69_bib22","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/1523-1747.ep12298415","article-title":"Successful treatment of chronic leg ulcers with epidermal equivalents generated from cultured autologous outer root sheath cells","volume":"107","author":"Limat","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1067\/mjd.2003.69_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0002-9610(99)80258-X","article-title":"Transplantation of keratinocytes in the treatment of wounds","volume":"170","author":"Myers","year":"1995","journal-title":"Am J Surg"},{"key":"10.1067\/mjd.2003.69_bib24","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s004030050417","article-title":"Human melanocytes grown in epidermal equivalents transfer their melanin to follicular outer root sheath keratinocytes","volume":"291","author":"Limat","year":"1999","journal-title":"Arch Dermatol Res"},{"key":"10.1067\/mjd.2003.69_bib25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0190-9622(90)70197-P","article-title":"Cultured epidermal autografts and allografts: a study of differentiation and allograft survival","volume":"23","author":"Phillips","year":"1990","journal-title":"J Am Acad Dermatol"},{"key":"10.1067\/mjd.2003.69_bib26","first-page":"170","article-title":"Treatment of leg ulcers with cultured epithelial autografts: treatment protocol and five year experience","volume":"7","author":"Limova","year":"1995","journal-title":"Wounds"},{"key":"10.1067\/mjd.2003.69_bib27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0190-9622(91)70015-T","article-title":"Grafting of venous leg ulcers. An intraindividual comparison between cultured skin equivalents and full-thickness skin punch grafts","volume":"24","author":"Mol","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"10.1067\/mjd.2003.69_bib28","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1126\/science.276.5309.75","article-title":"Wound healing-aiming for perfect skin regeneration","volume":"276","author":"Martin","year":"1997","journal-title":"Science"},{"key":"10.1067\/mjd.2003.69_bib29","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0306-3623(97)00419-9","article-title":"Regulation of keratinocyte proliferation","volume":"30","author":"Gniadnecki","year":"1998","journal-title":"Gen Pharmacol"},{"key":"10.1067\/mjd.2003.69_bib30","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1242\/jcs.112.12.1843","article-title":"Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism","volume":"112","author":"Maas-Szabowski","year":"1999","journal-title":"J Cell Sci"},{"key":"10.1067\/mjd.2003.69_bib31","first-page":"47","article-title":"Growth factors and wound healing","author":"Falanga","year":"1993"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962202614732?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962202614732?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T05:16:50Z","timestamp":1622783810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962202614732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["S0190962202614732"],"URL":"https:\/\/doi.org\/10.1067\/mjd.2003.69","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2003,2]]}}}