{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:45:06Z","timestamp":1791380706692,"version":"4.3.3"},"reference-count":75,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2000,8]]},"DOI":"10.1067\/mob.2000.107946","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T00:15:48Z","timestamp":1027556148000},"page":"S65-S75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"S","title":["Management of side effects and complications in medical abortion"],"prefix":"10.1067","volume":"183","author":[{"given":"Beth","family":"Kruse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Poppema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell D.","family":"Creinin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/mob.2000.107946_bib1","first-page":"197","article-title":"Abortion complications: prevention and management","author":"Lichtenberg","year":"1999"},{"key":"10.1067\/mob.2000.107946_bib2","first-page":"129","article-title":"Complications of first-trimester abortion: a report of 170,000 cases","volume":"76","author":"Hakim-Elahi","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib3","doi-asserted-by":"crossref","first-page":"142","DOI":"10.2307\/2136257","article-title":"Acceptability of medical abortion in early pregnancy","volume":"27","author":"Winikoff","year":"1995","journal-title":"Fam Plann Perspect"},{"key":"10.1067\/mob.2000.107946_bib4","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1001\/archfami.7.4.360","article-title":"Acceptability and feasibility of early pregnancy termination by mifepristone-misoprostol: results of a large multicenter trial in the United States","volume":"7","author":"Winikoff","year":"1998","journal-title":"Arch Fam Med"},{"key":"10.1067\/mob.2000.107946_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0010-7824(96)00114-X","article-title":"Methotrexate and misoprostol for early abortion: a multicenter trial. Acceptability","volume":"54","author":"Creinin","year":"1996","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib6","first-page":"95","article-title":"Sequelae of abortion","author":"Grimes","year":"1995"},{"key":"10.1067\/mob.2000.107946_bib7","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJM199305273282101","article-title":"Early termination of pregnancy with mifepristone (RU 486) and the orally active prostaglandin misoprostol","volume":"328","author":"Peyron","year":"1993","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"10.1067\/mob.2000.107946_bib8","first-page":"85","article-title":"Termination of early pregnancy (up to 63 days of amenorrhea) with mifepristone (RU486) and increasing doses of misoprostol","volume":"40","author":"Aub\u00e9ny","year":"1995","journal-title":"Int J Fertil Menopausal Stud"},{"key":"10.1067\/mob.2000.107946_bib9","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1056\/NEJM199804303381801","article-title":"Early pregnancy termination with mifepristone and misoprostol in the United States","volume":"338","author":"Spitz","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1067\/mob.2000.107946_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0010-7824(98)00150-4","article-title":"Low-dose mifepristone 200mg and vaginal misoprostol for abortion","volume":"59","author":"Schaff","year":"1999","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib11","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0010-7824(96)00080-7","article-title":"Methotrexate and misoprostol for early abortion: a multicenter trial. I. Safety and efficacy","volume":"53","author":"Creinin","year":"1996","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib12","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0029-7844(97)00266-4","article-title":"Medical abortion with oral methotrexate and vaginal misoprostol","volume":"90","author":"Creinin","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib13","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0010-7824(96)00206-5","article-title":"Analysis of failure in medical abortion","volume":"54","author":"Winikoff","year":"1996","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib14","first-page":"1","article-title":"Early abortion: surgical and medical options","volume":"20","author":"Creinin","year":"1997","journal-title":"Curr Probl Obstet Gynecol Fertil"},{"key":"10.1067\/mob.2000.107946_bib15","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1001\/jama.1994.03520150058037","article-title":"Methotrexate and misoprostol vs misoprostol alone for early abortion","volume":"272","author":"Creinin","year":"1994","journal-title":"JAMA"},{"key":"10.1067\/mob.2000.107946_bib16","first-page":"353","article-title":"Vaginal misoprostol administered at home after mifepristone (RU486) for abortion","volume":"44","author":"Schaff","year":"1997","journal-title":"J Fam Pract"},{"key":"10.1067\/mob.2000.107946_bib17","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/S0029-7844(97)81439-1","article-title":"Medical abortion in early pregnancy: a review of the evidence","volume":"89","author":"Grimes","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib18","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1093\/humrep\/13.10.2962","article-title":"An effective regimen for early medical abortion: a report of 2000 consecutive cases","volume":"13","author":"Ashok","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1067\/mob.2000.107946_bib19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0002-9378(99)70146-8","article-title":"Success rates and estimation of gestational age for medical abortion vary with transvaginal ultrasonographic criteria","volume":"180","author":"Creinin","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1037\/h0034767","article-title":"Effects of accurate expectations about sensations on the sensory and distress components of pain","volume":"27","author":"Johnson","year":"1973","journal-title":"J Pers Soc Psychol"},{"key":"10.1067\/mob.2000.107946_bib21","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1056\/NEJM199508313330901","article-title":"Methotrexate and misoprostol to terminate early pregnancy","volume":"333","author":"Hausknecht","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1067\/mob.2000.107946_bib22","first-page":"198","article-title":"Methotrexate and misoprostol for early abortion","volume":"28","author":"Schaff","year":"1996","journal-title":"Fam Med"},{"key":"10.1067\/mob.2000.107946_bib23","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0010-7824(99)00032-3","article-title":"Early abortion with 800 \u03bcg of misoprostol by the vaginal route","volume":"59","author":"Carbonell","year":"1999","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib24","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0010-7824(99)00003-7","article-title":"Side effects of mifepristone-misoprostol abortion versus surgical abortion: data from a trial in China, Cuba, and India","volume":"59","author":"Elul","year":"1999","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0010-7824(96)00252-1","article-title":"The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK Multicentre Study\u2014final results","volume":"55","author":"Urquhart","year":"1997","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib26","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0010-7824(97)00120-0","article-title":"Effect of nonsteroidal anti-inflammatory drugs on the action of misoprostol in a regimen for early abortion","volume":"56","author":"Creinin","year":"1997","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib27","first-page":"179","article-title":"Effects of the antiprogesterone RU 486 in early pregnancy and during the menstrual cycle","author":"Herrmann","year":"1985"},{"key":"10.1067\/mob.2000.107946_bib28","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0020-7292(98)00102-7","article-title":"Blood loss with mifepristone-misoprostol abortion: measures from a trial in China, Cuba and India","volume":"63","author":"Harper","year":"1998","journal-title":"Int J Gynecol Obstet"},{"key":"10.1067\/mob.2000.107946_bib29","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1056\/NEJM199504133321502","article-title":"Induction of abortion with mifepristone (RU 486) and oral or vaginal misoprostol","volume":"332","author":"El-Refaey","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1067\/mob.2000.107946_bib30","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1093\/oxfordjournals.humrep.a138287","article-title":"The effect of dose of mifepristone and gestation on the efficacy of medical abortion with mifepristone and misoprostol","volume":"8","author":"McKinley","year":"1993","journal-title":"Hum Reprod"},{"key":"10.1067\/mob.2000.107946_bib31","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1111\/j.1471-0528.1992.tb13707.x","article-title":"Induction of abortion with mifepristone and misoprostol in early pregnancy","volume":"99","author":"Thong","year":"1992","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1067\/mob.2000.107946_bib32","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0010-7824(97)00173-X","article-title":"Medical abortion with methotrexate 75 mg intramuscularly and vaginal misoprostol","volume":"56","author":"Creinin","year":"1997","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib33","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0010-7824(99)00016-5","article-title":"Outcomes of suction curettage and mifepristone abortion in the United States: a prospective comparison study","volume":"59","author":"Jensen","year":"1999","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib34","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0002-9378(97)70511-8","article-title":"Safety, efficacy, and acceptability of medical abortion in China, Cuba, and India: a comparative trial of mifepristone-misoprostol versus surgical abortion","volume":"176","author":"Winikoff","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib35","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/00016349209021052","article-title":"Medical termination of early pregnancy with mifepristone (RU 486) followed by a prostaglandin analogue","volume":"71","author":"Ulmann","year":"1992","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1067\/mob.2000.107946_bib36","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1001\/archfami.4.9.774","article-title":"Combined methotrexate and misoprostol for early induced abortion","volume":"4","author":"Schaff","year":"1995","journal-title":"Arch Fam Med"},{"key":"10.1067\/mob.2000.107946_bib37","first-page":"91","article-title":"Medical abortion in early pregnancy","author":"Creinin","year":"1999"},{"key":"10.1067\/mob.2000.107946_bib38","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2165\/00003495-199856040-00002","article-title":"Ergot alkaloids: current status and review of clinical pharmacology and therapeutic use compared with other oxytocics in obstetrics and gynecology","volume":"56","author":"de Groot","year":"1998","journal-title":"Drugs"},{"key":"10.1067\/mob.2000.107946_bib39","first-page":"248","article-title":"A medical approach to management of spontaneous abortion using misoprostol","volume":"76","author":"Chung","year":"1997","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1067\/mob.2000.107946_bib40","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0029-7844(97)81438-X","article-title":"Misoprostol for medical evacuation of early pregnancy failure","volume":"89","author":"Creinin","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib41","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1111\/j.1471-0528.1998.tb10269.x","article-title":"Vaginal misoprostol alone is effective in the treatment of missed abortion","volume":"105","author":"Zalanyi","year":"1998","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1067\/mob.2000.107946_bib42","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S0002-9378(98)70212-1","article-title":"Rectal misoprostol in the prevention of postpartum hemorrhage: a placebo-controlled trial","volume":"179","author":"Bamigboye","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib43","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1034\/j.1600-0412.1998.770209.x","article-title":"Randomized comparison of rectal misoprostol with Syntometrine for management of third stage of labor","volume":"77","author":"Bamigboye","year":"1998","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1067\/mob.2000.107946_bib44","first-page":"255","article-title":"Oral misoprostol for third stage of labor: a randomized placebo-controlled trial","volume":"94","author":"Surbek","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib45","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00006250-199808000-00011","article-title":"Rectally administered misoprostol for the treatment of postpartum hemorrhage unresponsive to oxytocin and ergometrine: a descriptive study","volume":"92","author":"O\u2019Brien","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib46","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0010-7824(93)90079-M","article-title":"Methotrexate and misoprostol for early abortion","volume":"48","author":"Creinin","year":"1993","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib47","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0010-7824(97)00021-8","article-title":"Abortion induced with methotrexate and misoprostol: a comparison of various protocols","volume":"55","author":"Wiebe","year":"1997","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib48","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/0002-9378(95)90652-5","article-title":"A randomized trial comparing misoprostol three and seven days after methotrexate for early abortion","volume":"173","author":"Creinin","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib49","series-title":"Recommended guidelines for use of methotrexate and misoprostol in early abortion","author":"National Abortion Federation","year":"1996"},{"key":"10.1067\/mob.2000.107946_bib50","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0010-7824(93)90114-M","article-title":"Methotrexate for abortion at \u226442 days gestation","volume":"48","author":"Creinin","year":"1993","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib51","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1148\/radiology.186.1.8416592","article-title":"Endovaginal US and Doppler findings after first-trimester abortion","volume":"186","author":"Dillon","year":"1993","journal-title":"Radiology"},{"key":"10.1067\/mob.2000.107946_bib52","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/(SICI)1097-0096(199606)24:5<257::AID-JCU5>3.0.CO;2-D","article-title":"Transvaginal sonohysterography: a new aid in the diagnosis of residual trophoblastic tissue","volume":"24","author":"Wolman","year":"1996","journal-title":"J Clin Ultrasound"},{"key":"10.1067\/mob.2000.107946_bib53","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000009954","article-title":"Evaluation of the accuracy of transvaginal sonography for the assessment of retained products of conception after spontaneous abortion","volume":"45","author":"Chung","year":"1998","journal-title":"Gynecol Obstet Invest"},{"key":"10.1067\/mob.2000.107946_bib54","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0010-7824(97)00121-2","article-title":"Misoprostol 3, 4,, or 5 days after methotrexat for early abortion: a randomized trial","volume":"56","author":"Carbonell","year":"1997","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib55","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0010-7824(98)00004-3","article-title":"Oral methotrexate and vaginal misoprostol for early abortion","volume":"57","author":"Carbonell","year":"1998","journal-title":"Contraception"},{"key":"10.1067\/mob.2000.107946_bib56","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000010090","article-title":"25 mg or 50 mg of oral methotrexate followed by vaginal misoprostol 7 days after for early abortion","volume":"47","author":"Carbonell","year":"1999","journal-title":"Gynecol Obstet Invest"},{"key":"10.1067\/mob.2000.107946_bib57","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1056\/NEJM199003083221001","article-title":"Voluntary interruption of pregnancy with mifepristone (RU 486) and a prostaglandin analogue: a large scale French experience","volume":"322","author":"Silvestre","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1067\/mob.2000.107946_bib58","first-page":"1","volume":"47","year":"1998","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1067\/mob.2000.107946_bib59","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/0029-7844(96)00252-9","article-title":"Life-threatening neutropenia following methotrexate treatment of ectopic pregnancy: a report of two cases","volume":"88","author":"Isaacs","year":"1996","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib60","first-page":"884","article-title":"Antibiotics at the time of induced abortion: the case for universal prophylaxis based on a meta-analysis","volume":"87","author":"Sawaya","year":"1996","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib61","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/0029-7844(95)00035-P","article-title":"A randomized trial of prophylactic doxycycline for curettage in incomplete abortion","volume":"85","author":"Prieto","year":"1995","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib62","first-page":"55","article-title":"Mif\u00e9pristone: risque t\u00e9raogenes","author":"Goujard","year":"1997"},{"key":"10.1067\/mob.2000.107946_bib63","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/tera.1420360111","article-title":"Pathogenesis of median facial clefts in mice treated with methotrexate","volume":"36","author":"Darab","year":"1987","journal-title":"Teratology"},{"key":"10.1067\/mob.2000.107946_bib64","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0002-9343(90)90522-F","article-title":"Outcome of first-trimester exposure to low-dose methotrexate in eight patients with rheumatic disease","volume":"88","author":"Kozlowski","year":"1990","journal-title":"Am J Med"},{"key":"10.1067\/mob.2000.107946_bib65","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/0140-6736(91)90046-R","article-title":"Misoprostol and congenital malformations [letter]","volume":"338","author":"Fonseca","year":"1991","journal-title":"Lancet"},{"key":"10.1067\/mob.2000.107946_bib66","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/ajmg.1320470113","article-title":"Limb deficiency with or without M\u00f6bius sequence in seven Brazilian children associated with misoprostol use in the first trimester of pregnancy","volume":"47","author":"Gonzalez","year":"1993","journal-title":"Am J Med Genet"},{"key":"10.1067\/mob.2000.107946_bib67","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1056\/NEJM199806253382604","article-title":"Use of misoprostol during pregnancy and M\u00f6bius\u2019 syndrome in infants","volume":"338","author":"Pastuszak","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1067\/mob.2000.107946_bib68","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0890-6238(98)00072-0","article-title":"Pregnancy outcome after exposure to misoprostol in Brazil: a prospective, controlled study","volume":"13","author":"Sch\u00fcler","year":"1999","journal-title":"Reprod Toxicol"},{"key":"10.1067\/mob.2000.107946_bib69","first-page":"46","volume":"44","year":"1995","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1067\/mob.2000.107946_bib70","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0015-0282(16)54527-0","article-title":"Mifepristone (RU486) alone or in combination with a prostaglandin analogue for termination of early pregnancy: a review","volume":"56","author":"Avrech","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1067\/mob.2000.107946_bib71","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0015-0282(16)55208-X","article-title":"Immunohistochemical analysis of estrogen and progesterone receptors in fallopian tubes during ectopic pregnancy","volume":"58","author":"Land","year":"1992","journal-title":"Fertil Steril"},{"key":"10.1067\/mob.2000.107946_bib72","first-page":"97","article-title":"ACOG practice bulletin","volume":"65","author":"Medical management of tubal pregnancy","year":"1999","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1067\/mob.2000.107946_bib73","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0015-0282(97)00284-7","article-title":"Medical treatment of ectopic pregnancy with methotrexate","volume":"68","author":"Thoen","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1067\/mob.2000.107946_bib74","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/S0002-9378(98)70343-6","article-title":"Analysis of three hundred fifteen ectopic pregnancies treated with single-dose methotrexate","volume":"178","author":"Lipscomb","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2000.107946_bib75","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0736-4679(98)00098-5","article-title":"Rupture of ectopic pregnancy after medical therapy with methotrexate: a case series","volume":"16","author":"Heard","year":"1998","journal-title":"J Emerg Med"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937800275303?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937800275303?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:37:22Z","timestamp":1757583442000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937800275303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":75,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["S0002937800275303"],"URL":"https:\/\/doi.org\/10.1067\/mob.2000.107946","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2000,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of side effects and complications in medical abortion","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1067\/mob.2000.107946","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}