{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:49:48Z","timestamp":1773409788965,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1067\/mob.2002.122598","type":"journal-article","created":{"date-parts":[[2002,8,24]],"date-time":"2002-08-24T18:14:26Z","timestamp":1030212866000},"page":"S198-S203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"S2","title":["Gastrointestinal factors in nausea and vomiting of pregnancy"],"prefix":"10.1067","volume":"186","author":[{"given":"Kenneth L.","family":"Koch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1067\/mob.2002.122598_bib1","first-page":"245","article-title":"A prospective study of nausea and vomiting during pregnancy","volume":"43","author":"Gadsby","year":"1993","journal-title":"Br J Gen Pract"},{"key":"10.1067\/mob.2002.122598_bib2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/j.1523-536X.1992.tb00671.x","article-title":"Nausea and vomiting during pregnancy: effects on the quality of women's lives","volume":"19","author":"O'Brien","year":"1992","journal-title":"Birth"},{"key":"10.1067\/mob.2002.122598_bib3","doi-asserted-by":"crossref","first-page":"781","DOI":"10.2165\/00003495-200059040-00005","article-title":"A risk-benefit assessment of pharmacological and non-pharmacological treatments for nausea and vomiting of pregnancy","volume":"59","author":"Mazzotta","year":"2000","journal-title":"Drugs"},{"key":"10.1067\/mob.2002.122598_bib4","first-page":"163","article-title":"Review article: clinical approaches to unexplained nausea and vomiting","volume":"3","author":"Koch","year":"1998","journal-title":"Adv Gastroenterol Hepatol Clin Nutr"},{"key":"10.1067\/mob.2002.122598_bib5","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1159\/000171608","article-title":"Dyspepsia of unknown origin. Pathophysiology, diagnosis and treatment","volume":"15","author":"Koch","year":"1997","journal-title":"Dig Dis"},{"key":"10.1067\/mob.2002.122598_bib6","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1136\/gut.45.2008.ii37","article-title":"Functional gastroduodenal disorders","volume":"45","author":"Talley","year":"1999","journal-title":"Gut"},{"key":"10.1067\/mob.2002.122598_bib7","first-page":"199","article-title":"Gastroduodenal motility","author":"Koch","year":"1998"},{"key":"10.1067\/mob.2002.122598_bib8","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1053\/gast.1996.v111.pm8690216","article-title":"Case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract","volume":"111","author":"Sanders","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1067\/mob.2002.122598_bib9","first-page":"290","article-title":"Electrogastrography","author":"Koch","year":"1993"},{"key":"10.1067\/mob.2002.122598_bib10","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/00004836-200009000-00007","article-title":"Reproducibility of gastric myoelectrical activity and the water load test in patients with dysmotility-like dyspepsia symptoms and in control subjects","volume":"31","author":"Koch","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"10.1067\/mob.2002.122598_bib11","first-page":"185","article-title":"Functional disorders of the stomach","volume":"7","author":"Koch","year":"1996","journal-title":"Sem Gastroenterol"},{"key":"10.1067\/mob.2002.122598_bib12","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/0016-5085(87)90843-2","article-title":"Spectral analysis of tachygastrias recorded during motion sickness","volume":"92","author":"Stern","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1067\/mob.2002.122598_bib13","first-page":"E578","article-title":"Hypothalamic and gastric myoelectrical responses during vection-induced nausea in healthy Chinese subjects","volume":"265","author":"Xu","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2002.122598_bib14","first-page":"E304","article-title":"Gastric myoelectrical and endogenous neuroendocrine responses to illusory self-motion in man","volume":"258","author":"Koch","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2002.122598_bib15","first-page":"G418","article-title":"Differential symptomatic and electrogastrographic effects of distal and proximal human gastric distention","volume":"275","author":"Ladabaum","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2002.122598_bib16","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/0016-5085(85)90022-8","article-title":"Glucagon-evoked gastric dysrhythmias in humans shown by an improved electrogastrographic technique","volume":"88","author":"Abell","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1067\/mob.2002.122598_bib17","first-page":"A696","article-title":"Effect of ondansetron on morphine-induced nausea, gastric myoelectrical activity and plasma vasopressin levels in healthy humans","volume":"110","author":"Koch","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1067\/mob.2002.122598_bib18","first-page":"G506","article-title":"Progesterone and estrogen are potential mediators of gastric slow wave dysrhythmias in nausea of pregnancy","volume":"270","author":"Walsh","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2002.122598_bib19","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1023\/A:1026647417465","article-title":"Diabetic gastropathy: gastric neuromuscular dysfunction in diabetes mellitus. A review of symptoms, pathophysiology, and treatment","volume":"44","author":"Koch","year":"1999","journal-title":"Dig Dis Sci"},{"key":"10.1067\/mob.2002.122598_bib20","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1007\/BF01308614","article-title":"Electrogastrography in patients with gastroparesis and effect of long-term cisapride","volume":"38","author":"Rothstein","year":"1993","journal-title":"Dig Dis Sci"},{"key":"10.1067\/mob.2002.122598_bib21","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/BF01537244","article-title":"Gastric dysrhythmias and nausea of pregnancy","volume":"35","author":"Koch","year":"1990","journal-title":"Dig Dis Sci"},{"key":"10.1067\/mob.2002.122598_bib22","first-page":"G855","article-title":"Protein meals reduce nausea and gastric slow wave dysrhythmic activity in first trimester pregnancy","volume":"277","author":"Jednak","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2002.122598_bib23","first-page":"266","article-title":"Effect of hypo- and hyper-thyroidism on gastric myoelectrical activity and gastric emptying","volume":"13","author":"Gunsar","year":"2001","journal-title":"Neurogastroenterol Mot"},{"key":"10.1067\/mob.2002.122598_bib24","first-page":"731","article-title":"Therapy of nausea and vomiting","author":"Koch","year":"2000"},{"key":"10.1067\/mob.2002.122598_bib25","doi-asserted-by":"crossref","first-page":"704","DOI":"10.7326\/0003-4819-126-9-199705010-00005","article-title":"Intractable nausea presenting as gastroesophageal reflux disease","volume":"126","author":"Brzana","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1067\/mob.2002.122598_bib26","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/0002-9378(95)90359-3","article-title":"Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial","volume":"173","author":"Vutyavanich","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2002.122598_bib27","first-page":"269","article-title":"The effect of liquid carbohydrate and protein meals on gastric tachyarrhythmia and susceptibility to vection-induced motion sickness","volume":"13","author":"Levine","year":"2001","journal-title":"Neurogastroenterol Mot"},{"key":"10.1067\/mob.2002.122598_bib28","first-page":"266","article-title":"Ginger reduces hyperglycemia-induced gastric dysrhythmias in nausea in healthy humans: possible mediation by inhibiting the action of endogenous prostaglandins","volume":"13","author":"Gonlachanvit","year":"2001","journal-title":"Neurogastroenterol Mot"},{"key":"10.1067\/mob.2002.122598_bib29","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1177\/014107688808100813","article-title":"P6 acupressure reduces morning sickness","volume":"81","author":"Dundee","year":"1988","journal-title":"J R Soc Med"},{"key":"10.1067\/mob.2002.122598_bib30","first-page":"603","article-title":"Suppression of pregnancy-induced nausea and vomiting with sensory afferent stimulation","volume":"38","author":"Evans","year":"1993","journal-title":"J Reprod Med"},{"key":"10.1067\/mob.2002.122598_bib31","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1023\/A:1018878324327","article-title":"Tricyclic antidepressants for functional nausea and vomiting: clinical outcome in 37 patients","volume":"43","author":"Prakash","year":"1998","journal-title":"Dig Dis Sci"},{"key":"10.1067\/mob.2002.122598_bib32","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/BF02088230","article-title":"Safety of first trimester exposure to histamine H2 blockers: a prospective cohort study","volume":"41","author":"Magee","year":"1996","journal-title":"Dig Dis Sci"},{"key":"10.1067\/mob.2002.122598_bib33","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0002-9378(98)70072-9","article-title":"Safety of omeprazole during pregnancy: a multi-centre prospective cohort study","volume":"179","author":"Lalkin","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2002.122598_bib34","first-page":"1128","article-title":"Drugs and pregnancy","volume":"338","author":"Koren","year":"1998","journal-title":"Am J Med"},{"key":"10.1067\/mob.2002.122598_bib35","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/S0002-9378(96)70213-2","article-title":"Droperidol and diphenhydramine in the management of hyperemesis gravidarum","volume":"174","author":"Nageotte","year":"1996","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937802800187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937802800187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:58:21Z","timestamp":1757584701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937802800187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S0002937802800187"],"URL":"https:\/\/doi.org\/10.1067\/mob.2002.122598","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gastrointestinal factors in nausea and vomiting of pregnancy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1067\/mob.2002.122598","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2002 Published by Mosby, Inc.","name":"copyright","label":"Copyright"}]}}