{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:48:18Z","timestamp":1761580098079},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1067\/mob.2003.102","type":"journal-article","created":{"date-parts":[[2003,2,11]],"date-time":"2003-02-11T16:25:29Z","timestamp":1044980729000},"page":"84-91","source":"Crossref","is-referenced-by-count":15,"title":["Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pig"],"prefix":"10.1067","volume":"188","author":[{"given":"Jorge A.","family":"Carvajal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loren P.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl P.","family":"Weiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1067\/mob.2003.102_bib1","first-page":"484","article-title":"Preterm labor and delivery","author":"Creasy","year":"1994"},{"key":"10.1067\/mob.2003.102_bib2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/1097-4652(200009)184:3<409::AID-JCP16>3.0.CO;2-K","article-title":"Molecular mechanism of cGMP-mediated smooth muscle relaxation","volume":"184","author":"Carvajal","year":"2000","journal-title":"J Cell Physiol"},{"key":"10.1067\/mob.2003.102_bib3","first-page":"216","article-title":"Parturition","author":"Cunningham","year":"1997"},{"key":"10.1067\/mob.2003.102_bib4","article-title":"The human fetal membranes and decidua as a model for paracrine interactions","author":"Bryant-Greenwood","year":"1998"},{"key":"10.1067\/mob.2003.102_bib5","first-page":"1479","article-title":"Human fetal membranes inhibit spontaneous uterine contractions","volume":"77","author":"Collins","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1067\/mob.2003.102_bib6","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/humrep\/16.4.638","article-title":"Chorion releases a factor that inhibits oxytocin-stimulated myometrial contractility in the pregnant guinea pig","volume":"16","author":"Carvajal","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1067\/mob.2003.102_bib7","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1210\/endo.135.6.7988434","article-title":"Pregnancy increases guanosine 3\u2032,5\u2032-monophosphate in the myometrium independent of nitric oxide synthesis","volume":"135","author":"Weiner","year":"1994","journal-title":"Endocrinology"},{"key":"10.1067\/mob.2003.102_bib8","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/0002-9378(95)90500-6","article-title":"Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy","volume":"172","author":"Buhimschi","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2003.102_bib9","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1172\/JCI927","article-title":"Hemoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy","volume":"101","author":"Acevedo","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1067\/mob.2003.102_bib10","first-page":"89","article-title":"Prostaglandin receptors in lower segment myometrium during gestation and labor","volume":"93","author":"Brodt-Eppley","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1067\/mob.2003.102_bib11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1098\/rspb.1993.0002","article-title":"Properties of large-conductance K+ channels in human myometrium during pregnancy and labour","volume":"251","author":"Khan","year":"1993","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"10.1067\/mob.2003.102_bib12","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0002-9378(98)70543-5","article-title":"Activation of large-conductance potassium channels in pregnant human myometrium by pinacidil","volume":"178","author":"Khan","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2003.102_bib13","first-page":"885","article-title":"Activation of guanosine 3\u2032,5\u2032-cyclic monophosphate (cGMP)-dependent protein kinase in rabbit aorta by nitroglycerin and sodium nitroprusside","volume":"283","author":"Patel","year":"1997","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1067\/mob.2003.102_bib14","doi-asserted-by":"crossref","first-page":"C1668","DOI":"10.1152\/ajpcell.1998.275.6.C1668","article-title":"Nitric oxide relaxes human myometrium by a cGMP-independent mechanism","volume":"275","author":"Bradley","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2003.102_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1139\/y97-187","article-title":"Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor","volume":"76","author":"Wang","year":"1998","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1067\/mob.2003.102_bib16","doi-asserted-by":"crossref","first-page":"183A","DOI":"10.1016\/S1071-5576(97)86666-X","article-title":"Effect of different agonists and antagonists on the stimulatory properties of chorion on myometrial cGMP production in pregnant guinea-pigs","volume":"5","author":"Buhimschi","year":"1998","journal-title":"J Soc Gynecol Invest"},{"key":"10.1067\/mob.2003.102_bib17","doi-asserted-by":"crossref","first-page":"C748","DOI":"10.1152\/ajpcell.1998.274.3.C748","article-title":"Regulation of cGMP-induced relaxation and cGMP-dependent protein kinase in rat myometrium during pregnancy","volume":"274","author":"Word","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2003.102_bib18","doi-asserted-by":"crossref","first-page":"C1751","DOI":"10.1152\/ajpcell.2000.279.6.C1751","article-title":"BK (Ca) channel activation by membrane-associated cGMP kinase may contribute to uterine quiescence in pregnancy","volume":"279","author":"Zhou","year":"2000","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1067\/mob.2003.102_bib19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0028-2243(95)02096-B","article-title":"Relaxant effects of nitric oxide and cyclic GMP on pregnant rat uterine longitudinal smooth muscle","volume":"60","author":"Izumi","year":"1995","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1067\/mob.2003.102_bib20","doi-asserted-by":"crossref","first-page":"11083","DOI":"10.1016\/S0021-9258(19)38560-6","article-title":"Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus","volume":"265","author":"Galvez","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1067\/mob.2003.102_bib21","doi-asserted-by":"crossref","first-page":"C1721","DOI":"10.1152\/ajpcell.1997.273.5.C1721","article-title":"Ca2+ dependence and pharmacology of large-conductance K+ channels in nonlabor and labor human uterine myocytes","volume":"273","author":"Khan","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1067\/mob.2003.102_bib22","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/humrep\/13.1.208","article-title":"Contribution of calcium-sensitive potassium channels to NS1619-induced relaxation in human pregnant myometrium","volume":"13","author":"Khan","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1067\/mob.2003.102_bib23","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/S0002-9378(98)70204-2","article-title":"Human fetal membranes release a Ca++ channel inhibitor","volume":"179","author":"Emery","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2003.102_bib24","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1067\/mob.2001.108855","article-title":"Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor","volume":"184","author":"Carroll","year":"2001","journal-title":"Am J Obstet Gynecol"},{"key":"10.1067\/mob.2003.102_bib25","first-page":"56","article-title":"The placenta of laboratory animals and man","author":"Ramsey","year":"1975"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937802714324?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937802714324?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T12:03:32Z","timestamp":1622721812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937802714324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["S0002937802714324"],"URL":"https:\/\/doi.org\/10.1067\/mob.2003.102","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}