{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:01:13Z","timestamp":1783382473651,"version":"3.54.6"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1067\/moe.2001.112949","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T04:21:43Z","timestamp":1027570903000},"page":"535-540","source":"Crossref","is-referenced-by-count":122,"title":["Reliability of toluidine blue application in the detection of oral epithelial dysplasia and in situ and invasive squamous cell carcinomas"],"prefix":"10.1067","volume":"91","author":[{"given":"Mirian Aparecida","family":"Onofre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Regina","family":"Sposto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e1udia Maria","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e3o","family":"Paulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/moe.2001.112949_bib1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.14219\/jada.archive.1964.0190","article-title":"In vivo staining test for delineation of oral intraepithelial neoplastic change: preliminary report","volume":"68","author":"Niebel","year":"1964","journal-title":"J Am Dent Assoc"},{"key":"10.1067\/moe.2001.112949_bib2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0002-9610(65)90052-8","article-title":"In vivo staining properties of oral cancer","volume":"110","author":"Shedd","year":"1965","journal-title":"Am J Surg"},{"key":"10.1067\/moe.2001.112949_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1001\/archsurg.1967.01330130018004","article-title":"Further appraisal of in vivo staining properties of oral cancer","volume":"95","author":"Shedd","year":"1967","journal-title":"Arch Surg"},{"key":"10.1067\/moe.2001.112949_bib4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3322\/canjclin.20.3.134","article-title":"The toluidine blue test in lesions of the oral cavity","volume":"20","author":"Myers","year":"1970","journal-title":"Cancer J Clin"},{"key":"10.1067\/moe.2001.112949_bib5","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/jso.2930040505","article-title":"Toluidine blue test for detection of carcinoma of the oral cavity: an evaluation","volume":"4","author":"Vahidy","year":"1972","journal-title":"J Surg Oncol"},{"key":"10.1067\/moe.2001.112949_bib6","first-page":"1161","article-title":"Toluidine blue staining of oral cancer and precancerous lesions","volume":"61","author":"Reddy","year":"1973","journal-title":"Indian J Med Res"},{"key":"10.1067\/moe.2001.112949_bib7","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/1097-0142(19800815)46:4<758::AID-CNCR2820460420>3.0.CO;2-8","article-title":"Reevaluation of toluidine blue application as a diagnostic adjunct in the detection of asymptomatic oral squamous carcinoma: a continuing prospective study of oral cancer III","volume":"46","author":"Mashberg","year":"1980","journal-title":"Cancer"},{"key":"10.1067\/moe.2001.112949_bib8","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1001\/jama.1981.03310480024019","article-title":"Tolonium (toluidine blue) rinse: a screening method for recognition of squamous carcinoma\u2014continuing prospective study of oral cancer IV","volume":"245","author":"Mashberg","year":"1981","journal-title":"JAMA"},{"key":"10.1067\/moe.2001.112949_bib9","first-page":"87","article-title":"Le d\u00e9pistage des cancers de la cavit\u00e9 buccale par le bleu de toluidine","volume":"137","author":"Barrellier","year":"1982","journal-title":"Actualiti\u00e9s Odonto-Stomatol"},{"key":"10.1067\/moe.2001.112949_bib10","doi-asserted-by":"crossref","first-page":"319","DOI":"10.14219\/jada.archive.1983.0063","article-title":"Final evaluation of tolonium chloride rinse for screening of high-risk patients with asymptomatic squamous carcinoma","volume":"106","author":"Mashberg","year":"1983","journal-title":"J Am Dent Assoc"},{"key":"10.1067\/moe.2001.112949_bib11","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0030-4220(84)90154-3","article-title":"Toluidine blue staining in the detection of oral precancerous and malignant lesions","volume":"57","author":"Silverman","year":"1984","journal-title":"Oral Surg"},{"key":"10.1067\/moe.2001.112949_bib12","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/0030-4220(89)90286-7","article-title":"Use of meta-analysis to evaluate tolonium chloride in oral cancer screening","volume":"67","author":"Rosenberg","year":"1989","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1067\/moe.2001.112949_bib13","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1600-0714.1992.tb00094.x","article-title":"Toluidine blue and lugol\u2019s iodine application in the assessment of oral malignant disease and lesions at risk of malignancy","volume":"21","author":"Epstein","year":"1992","journal-title":"J Oral Pathol Med"},{"key":"10.1067\/moe.2001.112949_bib14","first-page":"51","article-title":"Utilisation du bleu de toluidine dans le diagnostic des l\u00e9sions n\u00e9oplasiques de la cavit\u00e9 buccale","volume":"94","author":"Barrellier","year":"1993","journal-title":"Rev Stomatol Chir Maxillofac"},{"key":"10.1067\/moe.2001.112949_bib15","first-page":"782","article-title":"Assessment of the blue toluidine stain in oral lesions with suspicious of malignancy","volume":"74","author":"Onofre","year":"1995","journal-title":"J Dent Res"},{"key":"10.1067\/moe.2001.112949_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1600-0714.1996.tb00201.x","article-title":"Sensitivity and specificity of OraScan toluidine blue mouthrinse in the detection of oral cancer and precancer","volume":"25","author":"Warnakulasuriya","year":"1996","journal-title":"J Oral Pathol Med"},{"key":"10.1067\/moe.2001.112949_bib17","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S1079-2104(97)90117-7","article-title":"The utility of toluidine blue application as a diagnostic aid in patients previously treated for upper oropharyngeal carcinoma","volume":"83","author":"Epstein","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1067\/moe.2001.112949_bib18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0714.1996.tb00191.x","article-title":"An international collaborative group on oral white lesions","author":"Ax\u00e9ll","year":"1996","journal-title":"J Oral Pathol Med"},{"key":"10.1067\/moe.2001.112949_bib19","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1601-0825.1997.tb00026.x","article-title":"Potentially malignant epithelial oral lesions: discrepancies between clinical and histological diagnosis","volume":"3","author":"Onofre","year":"1997","journal-title":"Oral Diseases"},{"key":"10.1067\/moe.2001.112949_bib20","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1002\/1097-0142(197312)32:6<1436::AID-CNCR2820320622>3.0.CO;2-C","article-title":"A study of the appearance of early asymptomatic oral squamous cell carcinoma","volume":"32","author":"Mashberg","year":"1973","journal-title":"Cancer"},{"key":"10.1067\/moe.2001.112949_bib21","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/sj.bdj.4804055","article-title":"The clinical features and risk of malignant transformation in sublingual keratosis","volume":"144","author":"Kramer","year":"1978","journal-title":"Br Dent J"},{"issue":"suppl 1","key":"10.1067\/moe.2001.112949_bib22","first-page":"53","article-title":"Management options in potentially malignant and malignant oral epithelial lesions","volume":"10","author":"Lamey","year":"1993","journal-title":"Community Dental Health"},{"issue":"suppl 1","key":"10.1067\/moe.2001.112949_bib23","first-page":"43","article-title":"Clinical diagnostic methods for the detection of premalignant and early malignant oral lesions","volume":"10","author":"Scully","year":"1993","journal-title":"Community Dental Health"},{"key":"10.1067\/moe.2001.112949_bib24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/0030-4220(78)90383-3","article-title":"Definition of leukoplakia and related lesions: an aid to studies an oral precancer","volume":"46","author":"World Health Organization Collaborating Center for Oral Precancerous Lesions","year":"1978","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1067\/moe.2001.112949_bib25","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1111\/j.1600-0714.1985.tb00549.x","article-title":"Subjectivity in evaluating oral epithelial dysplasia, carcinoma in situ and initial carcinoma","volume":"14","author":"Pindborg","year":"1985","journal-title":"J Oral Pathol Med"},{"key":"10.1067\/moe.2001.112949_bib26","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0030-4220(85)90315-9","article-title":"Lichenoid dysplasic: a distinct histopathologic entity","volume":"30","author":"Krutchkoff","year":"1985","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1067\/moe.2001.112949_bib27","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/0030-4220(90)90113-7","article-title":"Candidal infection in oral lichen planus","volume":"70","author":"Hatchuel","year":"1990","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1067\/moe.2001.112949_bib28","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S1079-2104(98)90071-3","article-title":"The application of toluidine blue as a diagnostic adjunct in the detection of epithelial dysplasia","volume":"85","author":"Martin","year":"1998","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210401303177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210401303177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:10:16Z","timestamp":1703895016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079210401303177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["S1079210401303177"],"URL":"https:\/\/doi.org\/10.1067\/moe.2001.112949","relation":{},"ISSN":["1079-2104"],"issn-type":[{"value":"1079-2104","type":"print"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}