{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:46:21Z","timestamp":1783633581822,"version":"3.55.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2000,12,1]],"date-time":"2000-12-01T00:00:00Z","timestamp":975628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2000,12]]},"DOI":"10.1067\/msy.2000.110847","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T04:20:13Z","timestamp":1027570813000},"page":"888-894","source":"Crossref","is-referenced-by-count":29,"title":["Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization"],"prefix":"10.1016","volume":"128","author":[{"given":"Bhuvanesh","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C.","family":"Cigudosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Ghossein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok R.","family":"Shaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Poluri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkert B.","family":"Wreesmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Tuttle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatin P.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pulivarthi H.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/msy.2000.110847_bib1","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0002-9610(05)80729-9","article-title":"Prognostic factors in differentiated carcinoma of the thyroid gland","volume":"164","author":"Shah","year":"1992","journal-title":"Am J Surg"},{"key":"10.1067\/msy.2000.110847_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1098-2264(199605)16:1<1::AID-GCC1>3.0.CO;2-4","article-title":"Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells","volume":"16","author":"Pierotti","year":"1996","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1067\/msy.2000.110847_bib3","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1210\/jc.83.2.525","article-title":"Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas","volume":"83","author":"Ward","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1067\/msy.2000.110847_bib4","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1054\/bjoc.1999.0921","article-title":"Gene rearrangement and Chernobyl related thyroid cancers","volume":"82","author":"Santoro","year":"2000","journal-title":"Br J Cancer"},{"key":"10.1067\/msy.2000.110847_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0304-3835(96)04196-1","article-title":"p53 gene mutation in thyroid carcinoma","volume":"103","author":"Ho","year":"1996","journal-title":"Cancer Lett"},{"key":"10.1067\/msy.2000.110847_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/exmp.1995.1022","article-title":"Nuclear accumulation of MDM2 protein in well-differentiated papillary thyroid carcinomas","volume":"62","author":"Jennings","year":"1995","journal-title":"Exp Mol Pathol"},{"key":"10.1067\/msy.2000.110847_bib7","first-page":"1207","article-title":"RET\/PTC oncogene activation is an early event in thyroid carcinogenesis","volume":"11","author":"Viglietto","year":"1995","journal-title":"Oncogene"},{"key":"10.1067\/msy.2000.110847_bib8","first-page":"1253","article-title":"Comparative genomic hybridization: an overview","volume":"145","author":"Houldsworth","year":"1994","journal-title":"Am J Pathol"},{"key":"10.1067\/msy.2000.110847_bib9","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1086\/301973","article-title":"From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization","volume":"63","author":"Chen","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1067\/msy.2000.110847_bib10","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/S0002-9440(10)65407-7","article-title":"DNA copy number changes in thyroid carcinoma","volume":"154","author":"Hemmer","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1067\/msy.2000.110847_bib11","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/(SICI)1098-2264(199908)25:4<349::AID-GCC6>3.0.CO;2-D","article-title":"Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization","volume":"25","author":"Frisk","year":"1999","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1067\/msy.2000.110847_bib12","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1038\/bjc.1998.620","article-title":"Comparison of benign and malignant follicular thyroid tumours by comparative genomic hybridization","volume":"78","author":"Hemmer","year":"1998","journal-title":"Br J Cancer"},{"key":"10.1067\/msy.2000.110847_bib13","first-page":"547","article-title":"Frequent chromosomal DNA unbalance in thyroid oncocytic (H\u00fcrthle cell) neoplasms detected by comparative genomic hybridization","volume":"79","author":"Tallini","year":"1999","journal-title":"Lab Invest"},{"key":"10.1067\/msy.2000.110847_bib14","first-page":"1157","article-title":"Comparative genomic hybridization defines frequent loss on 16p in human anaplastic thyroid carcinoma","volume":"14","author":"Komoike","year":"1999","journal-title":"Int J Oncol"},{"key":"10.1067\/msy.2000.110847_bib15","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/(SICI)1098-2264(200003)27:3<244::AID-GCC4>3.0.CO;2-7","article-title":"Allelotyping of anaplastic thyroid carcinoma: frequent allelic losses on 1q, 9p, 11, 17, 19p, and 22q","volume":"27","author":"Kitamura","year":"2000","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1067\/msy.2000.110847_bib16","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1038\/sj.cdd.4400624","article-title":"Structure, function, and regulation of p63 and p73","volume":"6","author":"Levrero","year":"1999","journal-title":"Cell Death Differ"},{"key":"10.1067\/msy.2000.110847_bib17","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/00042737-199809000-00009","article-title":"Occurrence of thyroid carcinoma in Dutch patients with familial adenomatous polyposis. An epidemiological study and report of new cases","volume":"10","author":"van der Linde","year":"1998","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1067\/msy.2000.110847_bib18","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000059974","article-title":"TSC1 and TSC2 gene mutations in human kidney tumors","volume":"128","author":"Kajino","year":"1999","journal-title":"Contrib Nephrol"},{"key":"10.1067\/msy.2000.110847_bib19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1089\/thy.1999.9.119","article-title":"Expression of transforming growth factor beta1, beta2, and beta3 in multinodular goiters and differentiated thyroid carcinomas: a comparative study","volume":"9","author":"Kimura","year":"1999","journal-title":"Thyroid"},{"key":"10.1067\/msy.2000.110847_NEWBIB1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0092-8674(86)90785-3","article-title":"Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains","volume":"45","author":"Young","year":"1986","journal-title":"Cell"},{"key":"10.1067\/msy.2000.110847_bib21","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/335437a0","article-title":"The mas oncogene encodes an angiotensin receptor","volume":"335","author":"Jackson","year":"1988","journal-title":"Nature"},{"key":"10.1067\/msy.2000.110847_bib22","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1006\/geno.1996.0294","article-title":"Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h","volume":"34","author":"Chiang","year":"1996","journal-title":"Genomics"},{"key":"10.1067\/msy.2000.110847_bib23","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/376066a0","article-title":"Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium","volume":"376","author":"Fong","year":"1995","journal-title":"Nature"},{"key":"10.1067\/msy.2000.110847_bib24","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1101\/gad.13.14.1774","article-title":"Transcription elongation factor hSPT5 stimulates mRNA capping","volume":"13","author":"Wen","year":"1999","journal-title":"Genes Dev"},{"key":"10.1067\/msy.2000.110847_bib25","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0090-3019(97)00487-4","article-title":"Neurofibromatosis type 2 with multiple primary brain tumors in monozygotic twins","volume":"51","author":"Harada","year":"1999","journal-title":"Surg Neurol"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606000007042?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606000007042?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T03:15:15Z","timestamp":1576466115000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606000007042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,12]]}},"alternative-id":["S0039606000007042"],"URL":"https:\/\/doi.org\/10.1067\/msy.2000.110847","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2000,12]]}}}