{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:06:19Z","timestamp":1791846379838,"version":"4.3.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2001,12]]},"DOI":"10.1067\/msy.2001.118371","type":"journal-article","created":{"date-parts":[[2002,8,24]],"date-time":"2002-08-24T18:14:26Z","timestamp":1030212866000},"page":"1011-1018","source":"Crossref","is-referenced-by-count":96,"title":["In vitro accumulation of technetium-99m-sestamibi in human parathyroid mitochondria"],"prefix":"10.1016","volume":"130","author":[{"given":"Nophadol","family":"Hetrakul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.Cahid","family":"Civelek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole A.","family":"Stagg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Udelsman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1067\/msy.2001.118371_bib1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/ajcp\/55.5.523","article-title":"Serum calcium: surgery for hyperparathyroidism: results in 50,000 clinical patients","volume":"55","author":"Boonstra","year":"1971","journal-title":"J Clin Pathol"},{"key":"10.1067\/msy.2001.118371_bib2","first-page":"764","article-title":"Persistent postoperative hyperparathyroidism","volume":"151","author":"Martin","year":"1980","journal-title":"Surg Gynecol Obstet"},{"key":"10.1067\/msy.2001.118371_bib3","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1210\/jc.78.1.77","article-title":"Preoperative localization of parathyroid tissue with technetium-99m sestamibi 123-I subtraction scanning","volume":"78","author":"Thule","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1067\/msy.2001.118371_bib4","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/bjs.1800750202","article-title":"Localization studies in patients with primary hyperparathyroidism","volume":"75","author":"Thompson","year":"1988","journal-title":"Br J Surg"},{"key":"10.1067\/msy.2001.118371_bib5","first-page":"582","article-title":"Cost-effectiveness of preoperative localization studies in primary hyperparathyroid disease","volume":"219","author":"Roe","year":"1994","journal-title":"Ann Surg"},{"key":"10.1067\/msy.2001.118371_bib6","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S0039-6060(97)90201-4","article-title":"Minimally invasive parathyroidectomy facilitated by intraoperative nuclear mapping","volume":"122","author":"Norman","year":"1997","journal-title":"Surgery"},{"key":"10.1067\/msy.2001.118371_bib7","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1067\/msy.1998.92007","article-title":"Minimally invasive radioguided parathyroidectomy in the reoperative neck","volume":"124","author":"Norman","year":"1998","journal-title":"Surgery"},{"key":"10.1067\/msy.2001.118371_bib8","first-page":"639","article-title":"Prospective comparison of radionuclide, computed tomographic, sonographic, and magnetic resonance localization of parathyroid tumors","volume":"106","author":"Krubsack","year":"1989","journal-title":"Surgery"},{"key":"10.1067\/msy.2001.118371_bib9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1126\/science.6897930","article-title":"Heart imaging with cationic complexes of technetium","volume":"214","author":"Deutsch","year":"1981","journal-title":"Science"},{"key":"10.1067\/msy.2001.118371_bib10","first-page":"1350","article-title":"A new Tc-99m-labeled myocardial imaging agent, hexakis (t-Butylisonitrile)-technetium(I) [Tc-99m TBI]: initial experience in the human","volume":"25","author":"Holman","year":"1984","journal-title":"J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib11","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1097\/00006231-198911000-00003","article-title":"99 Tc m sestamibi: a new agent for parathyroid imaging","volume":"10","author":"Coakley","year":"1989","journal-title":"Nucl Med Commun"},{"key":"10.1067\/msy.2001.118371_bib12","first-page":"12","article-title":"Impact of technetium-99m-sestamibi localization on operative time and success of operations for primary hyperparathyroidism","volume":"60","author":"Casas","year":"1994","journal-title":"Am Surg"},{"key":"10.1067\/msy.2001.118371_bib13","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1210\/jc.81.1.346","article-title":"The accuracy of parathyroid gland localization in primary hyperparathyroidism using sestamibi radionuclide imaging","volume":"81","author":"Johnston","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1067\/msy.2001.118371_bib14","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0002-9610(05)80335-6","article-title":"Prospective comparison of technetium-99m-sestamibi\/iodine-123 radionuclide scan versus high resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism","volume":"166","author":"Casas","year":"1993","journal-title":"Am J Surg"},{"key":"10.1067\/msy.2001.118371_bib15","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0039-6060(97)90215-4","article-title":"Concise parathyroidectomy: the impact of preoperative SPECT 99mTc sestamibi scanning and intraoperative quick parathormone assay","volume":"122","author":"Carty","year":"1997","journal-title":"Surgery"},{"key":"10.1067\/msy.2001.118371_bib16","first-page":"40","article-title":"Thallium-technetium isotope subtraction scanning in primary hyperparathyroidism","volume":"34","author":"Maltby","year":"1989","journal-title":"J R Coll Surg Edinb"},{"key":"10.1067\/msy.2001.118371_bib17","first-page":"210","article-title":"Accuracy and cost-effectiveness of only delayed Tc-99m sestamibi SPECT scintigraphy in diagnosing parathyroid adenomas in individuals with primary hyperparathyroidism [abstract]","volume":"40","author":"Civelek","year":"1999","journal-title":"J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib18","first-page":"1801","article-title":"Detection and localization of parathyroid adenomas in patients with hyperparathyroidism using a single radionuclide imaging procedure with technetium-99m-sestamibi (double phase study)","volume":"33","author":"Taillefer","year":"1992","journal-title":"J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib19","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1161\/01.CIR.82.5.1826","article-title":"Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium (I) in cultured chick myocardial cells mitochondrial and plasma membrane potential dependence","volume":"82","author":"Piwnica-Worms","year":"1990","journal-title":"Circulation"},{"key":"10.1067\/msy.2001.118371_bib20","first-page":"1646","article-title":"Effect of mitochondrial and plasma membrane potentials on accumulation of hexakis (2-methoxyisobutylisonitrile) technetium (I) in cultured mouse fibroblasts","volume":"31","author":"Chiu","year":"1990","journal-title":"J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF02261241","article-title":"Effect of mitochondrial viability and metabolism on technetium-99m-sestamibi myocardial retention","volume":"20","author":"Crane","year":"1993","journal-title":"Eur J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib22","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1042\/bj0800649","article-title":"Biochemistry of dystrophic muscle: mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase","volume":"80","author":"Pennington","year":"1961","journal-title":"Biochem J"},{"key":"10.1067\/msy.2001.118371_bib23","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1073\/pnas.76.2.650","article-title":"Use of a lipophilic cation for determination of membrane potential in neuroblastoma-glioma hybrid cell suspensions","volume":"76","author":"Lichtshtein","year":"1979","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1067\/msy.2001.118371_bib24","first-page":"1441","article-title":"Preoperative localization of parathyroid lesions in hyperparathyroidism: relationship between technetium-99m-MIBI uptake and oxyphil cell content","volume":"39","author":"Carpentier","year":"1998","journal-title":"J Nucl Med"},{"key":"10.1067\/msy.2001.118371_bib25","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0039-6060(96)80052-3","article-title":"Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein","volume":"120","author":"Mitchell","year":"1996","journal-title":"Surgery"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003960600120419X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003960600120419X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T09:25:14Z","timestamp":1557393914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003960600120419X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["S003960600120419X"],"URL":"https:\/\/doi.org\/10.1067\/msy.2001.118371","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}