{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:27:18Z","timestamp":1773293238274,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,8,1]],"date-time":"2001-08-01T00:00:00Z","timestamp":996624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":5453,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2001,8]]},"DOI":"10.1067\/mtc.2001.112336","type":"journal-article","created":{"date-parts":[[2002,8,24]],"date-time":"2002-08-24T22:14:26Z","timestamp":1030227266000},"page":"310-317","source":"Crossref","is-referenced-by-count":19,"title":["Prevention of allograft heart valve failure in a rat model"],"prefix":"10.25013","volume":"122","author":[{"given":"Jean-Francois","family":"L\u00e9gar\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas B.","family":"Issekutz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Ruigrok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberley","family":"Creaser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg M.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy D.G.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1067\/mtc.2001.112336_bib1","first-page":"447","article-title":"Homograft replacement of the aortic valve","volume":"2","author":"Ross","year":"1962","journal-title":"Lancet."},{"key":"10.1067\/mtc.2001.112336_bib2","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/S0140-6736(66)90600-3","article-title":"Correction of pulmonary atresia with a homograft aortic valve","volume":"2","author":"Ross","year":"1966","journal-title":"Lancet."},{"key":"10.1067\/mtc.2001.112336_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0003-4975(10)65895-X","article-title":"Long-term performance of 555 aortic homografts in the aortic position","volume":"46","author":"Matsuki","year":"1988","journal-title":"Ann Thorac Surg."},{"key":"10.1067\/mtc.2001.112336_bib4","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S0022-5223(19)34168-6","article-title":"Degeneration of aortic valve allografts in young recipients","volume":"105","author":"Clarke","year":"1993","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib5","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/0003-4975(94)91347-1","article-title":"Donor-specific immune response after aortic valve allografting in the rat","volume":"57","author":"Zhao","year":"1994","journal-title":"Ann Thorac Surg."},{"key":"10.1067\/mtc.2001.112336_bib6","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/S0022-5223(96)70139-3","article-title":"Human aortic allografts elicit a donor-specific immune response","volume":"112","author":"Hogan","year":"1996","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0022-5223(96)70250-7","article-title":"Donor-specific cellular immune response against human cardiac valve allografts","volume":"112","author":"Hoekstra","year":"1996","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0022-5223(98)70449-0","article-title":"Evidence for rejection of homograft cardiac valves in infants","volume":"115","author":"Rajani","year":"1998","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib9","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1540-8191.1991.tb00345.x","article-title":"Immunogenicity, antigenicity and endothelial viability of aortic valves preserved at 4\u00b0C in a nutrient medium","volume":"6","author":"Lupinetti","year":"1991","journal-title":"J Card Surg."},{"key":"10.1067\/mtc.2001.112336_bib10","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0022-5223(97)70002-3","article-title":"Aortic valve grafts in the rat: evidence for rejection","volume":"114","author":"Moustapha","year":"1997","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib11","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1097\/00007890-199004000-00022","article-title":"Antigenicity of fresh and cryopreserved rat valve allografts","volume":"49","author":"Khatib","year":"1990","journal-title":"Transplantation."},{"key":"10.1067\/mtc.2001.112336_bib12","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0002-9149(92)90627-B","article-title":"Effects of homograft blood type and anatomic type on stenosis, regurgitation and calcium in homografts in the pulmonary position","volume":"70","author":"Shaddy","year":"1992","journal-title":"Am J Cardiol."},{"key":"10.1067\/mtc.2001.112336_bib13","doi-asserted-by":"crossref","first-page":"S146","DOI":"10.1016\/0003-4975(95)00290-2","article-title":"Short-course cyclosporin A therapy for definite allograft valve survival: immunosuppression in allograft valve operations","volume":"60","author":"Yankah","year":"1995","journal-title":"Ann Thorac Surg."},{"key":"10.1067\/mtc.2001.112336_bib14","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/S0003-4975(00)01677-5","article-title":"T lymphocytes are responsible for allograft aortic valve failure in rat","volume":"70","author":"L\u00e9gar\u00e9","year":"2000","journal-title":"Ann Thorac Surg."},{"key":"10.1067\/mtc.2001.112336_bib15","first-page":"3285","article-title":"Cellular adhesion molecules in transplantation","volume":"28","author":"Rodriguez-Iturbe","year":"1996","journal-title":"Transplant Proc."},{"key":"10.1067\/mtc.2001.112336_bib16","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0022-5223(94)70327-2","article-title":"Effects of preservation techniques on in vivo expression of adhesion molecules by aortic valve allografts","volume":"107","author":"Mulligan","year":"1994","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib17","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/00007890-199102000-00050","article-title":"Induced expression of endothelial-leukocyte adhesion molecules in human cardiac allografts","volume":"51","author":"Briscoe","year":"1991","journal-title":"Transplantation."},{"key":"10.1067\/mtc.2001.112336_bib18","volume":"Vol 1","year":"1993"},{"key":"10.1067\/mtc.2001.112336_bib19","first-page":"77","article-title":"Antigenicity and fate of cellular components of heart valve allografts","author":"Yankah","year":"1988"},{"key":"10.1067\/mtc.2001.112336_bib20","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/S0022-5223(99)70405-8","article-title":"Homograft valve failure in children","volume":"117","author":"Ross","year":"1999","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4049\/jimmunol.147.1.109","article-title":"Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat","volume":"147","author":"Issekutz","year":"1991","journal-title":"J Immunol."},{"key":"10.1067\/mtc.2001.112336_bib22","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/eji.1830210314","article-title":"Characterization of the rat leukocyte integrin, CD11\/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies","volume":"21","author":"Tamatami","year":"1991","journal-title":"Eur J Immunol."},{"key":"10.1067\/mtc.2001.112336_bib23","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1365-2567.1996.d01-695.x","article-title":"Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late antigen-4 integrins suppresses neutrophil and T-lymphocyte migration to the joints and improves clinical disease","volume":"88","author":"Issekutz","year":"1996","journal-title":"Immunology."},{"key":"10.1067\/mtc.2001.112336_bib24","doi-asserted-by":"crossref","first-page":"6258","DOI":"10.4049\/jimmunol.161.11.6258","article-title":"Blood monocyte migration to acute lung inflammation involves both CD11\/CD18 and very late activation antigen-4-dependent and independent pathways","volume":"161","author":"Li","year":"1998","journal-title":"J Immunol."},{"key":"10.1067\/mtc.2001.112336_bib25","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0022-5223(99)70324-7","article-title":"Allograft heart valves: the role of apoptosis-mediated cell loss","volume":"117","author":"Hilbert","year":"1998","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1067\/mtc.2001.112336_bib26","first-page":"3262","article-title":"Rapamycin and cyclosporine synergistically prolong heart and kidney allograft survival","volume":"23","author":"Stepkowski","year":"1991","journal-title":"Transplant Proc."},{"key":"10.1067\/mtc.2001.112336_bib27","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1053\/ejvs.1999.0936","article-title":"Immune response following fresh homograft replacement for aortoiliac graft infection","volume":"18","author":"Mirelli","year":"1999","journal-title":"Eur J Endovasc Surg"},{"key":"10.1067\/mtc.2001.112336_bib28","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/346425a0","article-title":"Adhesion receptors of the immune system","volume":"346","author":"Springer","year":"1990","journal-title":"Nature."},{"issue":"Suppl 1","key":"10.1067\/mtc.2001.112336_bib29","doi-asserted-by":"crossref","first-page":"S310","DOI":"10.1111\/j.1432-2277.1998.tb01141.x","article-title":"Transplantation tolerance by a combined therapy with sulfatide, anti-LFA-1\/ICAM-1 monoclonal antibodies and FK06 in rat cardiac transplantation","volume":"11","author":"Horimoto","year":"1998","journal-title":"Transplant Int."},{"key":"10.1067\/mtc.2001.112336_bib30","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1172\/JCI119457","article-title":"The cytokine-adhesion molecule cascade in ischemia\/reperfusion injury of the rat kidney","volume":"99","author":"Takada","year":"1997","journal-title":"J Clin Invest."},{"key":"10.1067\/mtc.2001.112336_bib31","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1097\/00007890-199305000-00051","article-title":"The efficacy of LFA-1 and VLA-4 antibody treatment in rat vascularized cardiac allograft rejection","volume":"55","author":"Paul","year":"1993","journal-title":"Transplantation."}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002252230160847X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002252230160847X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T14:51:50Z","timestamp":1680533510000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002252230160847X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,8]]}},"alternative-id":["S002252230160847X"],"URL":"https:\/\/doi.org\/10.1067\/mtc.2001.112336","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2001,8]]}}}