{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:27:53Z","timestamp":1770884873169,"version":"3.50.1"},"reference-count":71,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4580,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1067\/mva.2001.109336","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T04:22:51Z","timestamp":1027570971000},"page":"77-90","source":"Crossref","is-referenced-by-count":96,"title":["Low molecular weight heparin versus oral anticoagulants in the long-term treatment of deep venous thrombosis"],"prefix":"10.1067","volume":"33","author":[{"given":"Paloma","family":"L\u00f3pez-Beret","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Orgaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Fontcuberta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Doblas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adela","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Lozano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1067\/mva.2001.109336_bib1","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1056\/NEJM199105303242206","article-title":"Heparin","volume":"324","author":"Hirsh","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1067\/mva.2001.109336_bib2","first-page":"67","article-title":"Low molecular weight heparins in the initial treatment of deep venous thrombosis","volume":"15","author":"Volteas","year":"1996","journal-title":"Int Angiol"},{"key":"10.1067\/mva.2001.109336_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1055\/s-0038-1642676","article-title":"Treatment of venous thromboembolism","volume":"74","author":"ten Cate","year":"1995","journal-title":"Thromb Haemost"},{"issue":"Suppl 7","key":"10.1067\/mva.2001.109336_bib4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2165\/00003495-199600527-00006","article-title":"Comparison of the efficacy and safety of low molecular weight heparins and unfractionated heparin in the initial treatment of deep venous thrombosis: an updated meta-analysis","volume":"52","author":"Leizorovicz","year":"1996","journal-title":"Drugs"},{"key":"10.1067\/mva.2001.109336_bib5","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1055\/s-0038-1657575","article-title":"The treatment of deep vein thrombosis and pulmonary embolism","volume":"78","author":"Turkstra","year":"1997","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib6","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1055\/s-2007-996075","article-title":"Treatment of deep vein thrombosis with low molecular-weight heparins: a consensus stament of the Gesellschaft fur Thrombose und Hamostaseforschung (GTH)","volume":"23","author":"Harenberg","year":"1997","journal-title":"Semin Thromb Hemost"},{"key":"10.1067\/mva.2001.109336_bib7","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0025-7125(05)70012-2","article-title":"Unfractionated and low-molecular-with heparin: comparisons and current recommendations","volume":"82","author":"Pineo","year":"1998","journal-title":"Med Clin N Am"},{"key":"10.1067\/mva.2001.109336_bib8","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/0741-5214(93)90069-X","article-title":"Deep venous insufficiency: the relationship between lysis and subsequent reflux","volume":"18","author":"Meissner","year":"1993","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0741-5214(89)90223-1","article-title":"Spontaneous lysis of deep venous thrombi: rate and outcome","volume":"9","author":"Killewich","year":"1989","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib10","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0049-3848(83)90075-0","article-title":"Heparin and low molecular weight fraction enhances thrombolysis and by this pathway exercises a protective effect against thromboses","volume":"30","author":"Vairel","year":"1983","journal-title":"Thromb Res"},{"issue":"Suppl 6","key":"10.1067\/mva.2001.109336_bib11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0049-3848(86)91519-7","article-title":"Fibrinolytic activity of OP\/LMWH in experimental venous thrombosis [abstract]","volume":"44","author":"Barbanti","year":"1986","journal-title":"Thromb Res"},{"key":"10.1067\/mva.2001.109336_bib12","first-page":"64","article-title":"L'h\u00e8parine de bas poids mol\u00e9culare CY 222 (Choay) potentialise l'effect thrombolytique du t-PA chez le lapin avec thrombose exp\u00e9rimentale yugulaire","volume":"12","author":"Juhan-Vague","year":"1987","journal-title":"J Mal Vasc"},{"key":"10.1067\/mva.2001.109336_bib13","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0049-3848(92)90185-D","article-title":"The thrombolytic potency of LMW-heparin compared to urokinase in a rabbit jugular vein clot lysis model","volume":"66","author":"Bacher","year":"1992","journal-title":"Thromb Res"},{"key":"10.1067\/mva.2001.109336_bib14","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1055\/s-0038-1646021","article-title":"Potentiation by heparin fragments oh thrombolysis induced with human tissue-type plasminogen activator on human single-chain urokinase type plasminogen activator","volume":"58","author":"Stassen","year":"1987","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib15","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0049-3848(94)90029-9","article-title":"Regression of deep vein thrombosis by i.v.\u2014administration of a low molecular weight heparin. Results of a pilot study","volume":"73","author":"Kirchmaier","year":"1994","journal-title":"Thromb Res"},{"key":"10.1067\/mva.2001.109336_bib16","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1055\/s-2007-1000398","article-title":"Evaluation of hemostatic and fibrinolytic alterations associated with daily administration of low-molecular-weight heparins for a 12 week period","volume":"21","author":"Lojewski","year":"1995","journal-title":"Semin Thromb Hemost"},{"key":"10.1067\/mva.2001.109336_bib17","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0741-5214(97)70101-0","article-title":"Regression of proximal deep venous thrombosis is associated with fibrinolytic enhancement","volume":"26","author":"Killewich","year":"1997","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib18","first-page":"363","article-title":"Long term anticoagulation with low molecular weight heparin in outpatients with side effects on oral anticoagulants","volume":"31","author":"Harenberg","year":"1989","journal-title":"Nouv Rev Fr Hematol"},{"key":"10.1067\/mva.2001.109336_bib19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1055\/s-0038-1648837","article-title":"Low molecular weight heparin versus warfarin in the prevention of recurrences after deep vein thrombosis","volume":"72","author":"Pini","year":"1994","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1055\/s-0038-1642376","article-title":"Comparison of subcutaneous unfractionated heparin with a low molecular with heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin","volume":"71","author":"Monreal","year":"1994","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib21","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1177\/014107689608901108","article-title":"Anticoagulation in venous thrombosis","volume":"89","author":"Schulman","year":"1996","journal-title":"J R Soc Med"},{"key":"10.1067\/mva.2001.109336_bib22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s002770050336","article-title":"Subcutaneous low-molecular-weight heparin for treatment of Trousseau's syndrome","volume":"75","author":"Zuger","year":"1997","journal-title":"Ann Hematal"},{"key":"10.1067\/mva.2001.109336_bib23","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/(SICI)1097-0142(19970815)80:4<649::AID-CNCR1>3.0.CO;2-I","article-title":"Low-molecular-weight heparin in the management of Trousseau's syndrome","volume":"80","author":"Walsh-McMonagle","year":"1997","journal-title":"Cancer"},{"key":"10.1067\/mva.2001.109336_bib24","unstructured":"Suarez C, G\u00f3mez N, Casado LF, Nuche JM. Comparaci\u00f3n de la heparina subcut\u00e1nea con la de bajo peso molecular en el tratamiento a largo plazo de la TVP en pacientes mayores de 60 a\u00f1os. III Cong Nac Cap Flebol de la SEAC 1995; num 15. Costa de Almer\u00eda."},{"key":"10.1067\/mva.2001.109336_bib25","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.1182\/blood.V89.9.3236","article-title":"A histomorphometric comparison of the effects of heparin and low molecular weight heparin on cancellous bone in rats","volume":"89","author":"Muir","year":"1997","journal-title":"Blood"},{"key":"10.1067\/mva.2001.109336_bib26","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1056\/NEJM199603143341102","article-title":"Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home","volume":"334","author":"Koopman","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1067\/mva.2001.109336_bib27","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1056\/NEJM199506223322501","article-title":"Duration of anticoagulation trial study group: a comparison of six weeks with six month of oral anticoagulant therapy after a first episode of venous thromboembolism","volume":"332","author":"Schulman","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1067\/mva.2001.109336_bib28","first-page":"163","article-title":"Peripheral vascular ultrasongraphy","author":"Moneta","year":"1994"},{"key":"10.1067\/mva.2001.109336_bib29","first-page":"93","article-title":"Profilaxis de la trombosis en microcirug\u00eda vascular","author":"L\u00f3pez-Beret","year":"1990"},{"key":"10.1067\/mva.2001.109336_bib30","first-page":"113","article-title":"Evaluation of peripheral venous disease","volume":"27","author":"Merrit","year":"1992","journal-title":"Clin Diagn Ultrasound"},{"key":"10.1067\/mva.2001.109336_bib31","series-title":"Trombosis de miembros inferiores. Estudio comparativo entre ecograf\u00eda duplex\u2014doppler color y flebograf\u00eda","author":"Florensa","year":"1993"},{"key":"10.1067\/mva.2001.109336_bib32","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.0954-6820.1978.tb14908.x","article-title":"A prospective study of streptokinase and heparin in the treatment of deep venous thrombosis","volume":"203","author":"Arnesen","year":"1978","journal-title":"Acta Med Scand"},{"key":"10.1067\/mva.2001.109336_bib33","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/0741-5214(89)90011-6","article-title":"Quantification of venous reflux by means of duplex scanning","volume":"10","author":"Vasdekis","year":"1989","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib34","first-page":"190","article-title":"Die charakterisierung des poetthrombotischen refluxes mittels farbcodierter duplexsonographie","volume":"26","author":"Evers","year":"1997","journal-title":"Vasa"},{"key":"10.1067\/mva.2001.109336_bib35","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1055\/s-0038-1647660","volume":"65","year":"1991","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib36","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1055\/s-0037-1615089","article-title":"Comparison of a once daily with a twice daily subcutaneous low molecular weight heparin regimen in the treatment of deep vein thrombosis","volume":"79","author":"Charbonier","year":"1998","journal-title":"Thromb Haemost"},{"issue":"Suppl 1","key":"10.1067\/mva.2001.109336_bib37","first-page":"45","article-title":"Dalteparin prevention of recurrent DVT: a study versus warfarin [abstract]","volume":"24","author":"Kakkar","year":"1994","journal-title":"Haemostasis"},{"key":"10.1067\/mva.2001.109336_bib38","first-page":"124","article-title":"Tratamiento de las trombosis venosas profundas con fracciones de heparina de bajo peso molecular. Resultados preliminares","volume":"31","author":"Fontcuberta","year":"1986","journal-title":"Sangre"},{"issue":"Suppl 120","key":"10.1067\/mva.2001.109336_bib39","first-page":"430","article-title":"Subcutaneous administration of a low molecular weight heparin CY 222 compared with subcutaneous administration of standard heparin in patients with acute deep vein thrombosis","volume":"58","author":"Faivre","year":"1987","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib40","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0140-6736(92)91054-C","article-title":"Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis","volume":"339","author":"Prandoni","year":"1992","journal-title":"Lancet"},{"key":"10.1067\/mva.2001.109336_bib41","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1055\/s-0038-1656309","article-title":"Subcutaneous low molecular weight heparin versus subcutaneous unfractionated heparin in the treatment of deep vein thrombosis: a Polish multicenter trial","volume":"68","author":"Lopaciuk","year":"1992","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib42","first-page":"438","article-title":"Home treatment of deep vein thrombosis: a two years experience of a single institution","volume":"83","author":"Grau","year":"1998","journal-title":"Haematologica"},{"key":"10.1067\/mva.2001.109336_bib43","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1177\/106002809703100705","article-title":"Economic evaluation of the use of Nadroparin in the treatment of deep vein thrombosis in Switzerland","volume":"31","author":"Lloyd","year":"1997","journal-title":"Ann Pharmacother"},{"key":"10.1067\/mva.2001.109336_bib44","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1055\/s-0037-1614988","article-title":"Pharmaco-dynamics and tolerance of two Nadroparin formulations (10,250 and 20,500 anti Xa IU ml) delivered for 10 days at therapeutic dose","volume":"79","author":"Boneu","year":"1998","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib45","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1056\/NEJM199204093261502","article-title":"Subcutaneous low molecular weight heparin compared with continuous intravenous heparin in the treatment of proximal vein thrombosis","volume":"326","author":"Hull","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1067\/mva.2001.109336_bib46","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1056\/NEJM199211193272103","article-title":"Acenocoumarol and heparin compared with acenocoumarol alone in the initial treatment of proximal vein thrombosis","volume":"327","author":"Brandjes","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1067\/mva.2001.109336_bib47","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1161\/01.CIR.88.4.1730","article-title":"A simple ultrasound approach for detection of recurrent proximal-vein thromboses","volume":"88","author":"Prandoni","year":"1993","journal-title":"Circulation"},{"key":"10.1067\/mva.2001.109336_bib48","doi-asserted-by":"crossref","first-page":"511","DOI":"10.7326\/0003-4819-118-7-199304010-00005","article-title":"Risk factors for complications of chronic anticoagulation","volume":"118","author":"Fihn","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1067\/mva.2001.109336_bib49","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1001\/archinte.1993.00410130073007","article-title":"Bleeding complications in oral anticoagulant therapy: an analysis of risk factors","volume":"153","author":"van der Meer","year":"1993","journal-title":"Arch Intern Med"},{"key":"10.1067\/mva.2001.109336_bib50","doi-asserted-by":"crossref","first-page":"742","DOI":"10.7326\/0003-4819-126-9-199705010-00025","article-title":"Thrombocytosis associated with low-molecular-weight heparin [letter]","volume":"126","author":"Rizzieri","year":"1996","journal-title":"Ann Intern Med"},{"key":"10.1067\/mva.2001.109336_bib51","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1055\/s-2007-996087","article-title":"Low-molecular-weight heparin therapy and mortality","volume":"23","author":"Valentine","year":"1997","journal-title":"Semin Thromb Hemost"},{"key":"10.1067\/mva.2001.109336_bib52","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1001\/jama.1983.03340100023022","article-title":"Long-term sequelae of acute venous thrombosis","volume":"250","author":"Strandness","year":"1983","journal-title":"JAMA"},{"key":"10.1067\/mva.2001.109336_bib53","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1161\/01.CIR.93.1.74","article-title":"Prospective 12-year follow-up study of clinical and hemodynamic sequelae after vein thrombosis in low-risk patients (Zurich study)","volume":"93","author":"Franzeck","year":"1996","journal-title":"Circulation"},{"key":"10.1067\/mva.2001.109336_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-125-1-199607010-00001","article-title":"The long-term clinical course of acute deep venous thrombosis","volume":"125","author":"Prandoni","year":"1996","journal-title":"Ann Intern Med"},{"key":"10.1067\/mva.2001.109336_bib55","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0741-5214(98)70322-2","article-title":"Duplex ultrasound in the hemodynamic evaluation of the late sequelae of deep vein thrombosis","volume":"27","author":"Haenen","year":"1998","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib56","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0741-5214(97)70084-3","article-title":"Where does venous reflux start?","volume":"26","author":"Labropoulos","year":"1997","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib57","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0741-5214(95)70087-0","article-title":"New insights into the pathophysiology of venous ulceration using colour flow duplex imaging: implications for treatment","volume":"22","author":"Labropoulos","year":"1995","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib58","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1055\/s-0038-1656121","article-title":"On the relationship between changes in the deep veins evaluated by duplex sonography and the post-thrombotic syndrome 12 years after deep vein thrombosis","volume":"77","author":"Franzeck","year":"1997","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib59","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/(SICI)1097-0096(199801)26:1<7::AID-JCU3>3.0.CO;2-L","article-title":"Short and medium-term duplex sonography follow-up of deep venous thrombosis of the lower limbs","volume":"26","author":"Baud","year":"1998","journal-title":"J Clin Ultrasound"},{"key":"10.1067\/mva.2001.109336_bib60","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1161\/01.CIR.86.2.414","article-title":"Thrombus regression in deep venous thrombosis: quantification of spontaneous thrombolysis with duplex scanning","volume":"86","author":"Van Ramshorst","year":"1992","journal-title":"Circulation"},{"key":"10.1067\/mva.2001.109336_bib61","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/archsurg.1986.01400090078013","article-title":"A study of valve incompetence that developed in a experimental model of venous hypertension","volume":"121","author":"Van Bemmelen","year":"1986","journal-title":"Arch Surg"},{"key":"10.1067\/mva.2001.109336_bib62","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1148\/radiology.177.2.2217798","article-title":"Evolution of deep venous thrombosis: a prospective evaluation with US","volume":"177","author":"Murphy","year":"1990","journal-title":"Radiology"},{"key":"10.1067\/mva.2001.109336_bib63","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0741-5214(95)70289-X","article-title":"Venous duplex imaging follow-up of acute symptomatic deep venous thrombosis of the leg","volume":"21","author":"Caprini","year":"1995","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib64","first-page":"1018","article-title":"Quantitative venographic assessment of deep vein thrombosis in the evaluation of streptokinase and heparin therapy","volume":"89","author":"Marder","year":"1977","journal-title":"J Lab Clin Med"},{"key":"10.1067\/mva.2001.109336_bib65","first-page":"1","article-title":"Reporting standards in venous diseases","volume":"48","author":"Porter","year":"1982","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib66","first-page":"1","article-title":"Low molecular weight heparin (s)","volume":"9","author":"Barrowcliffe","year":"1955","journal-title":"Br J Haematol"},{"key":"10.1067\/mva.2001.109336_bib67","first-page":"538","article-title":"Does anticoagulation with heparin followed by daily long-term LMW heparin activate the fibrinolytic system?","volume":"69","author":"Bacher","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1067\/mva.2001.109336_bib68","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S1078-5884(96)80247-4","article-title":"The development of valvular incompetence after deep vein thrombosis: a 7 year follow-up study with duplex scanning","volume":"12","author":"Van Haarst","year":"1996","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1067\/mva.2001.109336_bib69","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0741-5214(89)90417-5","article-title":"Quantitative segmental evaluation of venous valvular reflux with duplex ultrasound scanning","volume":"10","author":"Van Bemmelen","year":"1989","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib70","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0741-5214(95)70271-7","article-title":"Relationship between changes in the deep venous system and the development of the postthrombotic syndrome after an acute episode of lower limb deep vein thrombosis: a one- to six-year follow-up","volume":"21","author":"Johnson","year":"1995","journal-title":"J Vasc Surg"},{"key":"10.1067\/mva.2001.109336_bib71","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/S0741-5214(94)70218-7","article-title":"The development of valvular incompetence after deep vein thrombosis: a follow-up study with duplex scanning","volume":"19","author":"Van Ramshorst","year":"1994","journal-title":"J Vasc Surg"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521401706258?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521401706258?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T03:58:53Z","timestamp":1576468733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521401706258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["S0741521401706258"],"URL":"https:\/\/doi.org\/10.1067\/mva.2001.109336","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}