{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T06:41:13Z","timestamp":1791700873979,"version":"4.3.4"},"reference-count":0,"publisher":"CSIRO Publishing","issue":"4","license":[{"start":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T00:00:00Z","timestamp":1757116800000},"content-version":"vor","delay-in-days":16076,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,9,1]]},"abstract":"<jats:p>Sheep were immunized with antigens extracted from third-instar larvae of L. cuprina. This procedure produced substantial titres of circulating antibody as measured by solid-phase radioimmunoassay or immunodiffusion or by both techniques. However, immunization did not confer protection against subsequent implant challenge with first-instar larvae. In vitro studies indicated that pooled sera from immunized sheep (mean immunodiffusion titre = 3) significantly reduced larval survival. Antigen specificity and the modulating effects of concomitant humoral responses to larval challenge are discussed in relation to the findings.<\/jats:p>","DOI":"10.1071\/bi9810411","type":"journal-article","created":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T02:54:32Z","timestamp":1467341672000},"page":"411-418","source":"Crossref","is-referenced-by-count":23,"title":["Immunization of Sheep With Larval Antigens of Lucilia cuprina"],"prefix":"10.1071","volume":"34","author":[{"given":"IJ","family":"O'Donnell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PE","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JA","family":"Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PS","family":"Hopkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[1981,9,1]]},"container-title":["Australian Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/bi\/article-pdf\/34\/4\/411\/1341854\/bi9810411.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/bi\/article-pdf\/34\/4\/411\/1341854\/bi9810411.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:18:55Z","timestamp":1762298335000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/bi\/article\/34\/4\/411\/195435\/Immunization-of-Sheep-With-Larval-Antigens-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,9,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1981,9,1]]},"published-print":{"date-parts":[[1981,9,1]]}},"URL":"https:\/\/doi.org\/10.1071\/bi9810411","relation":{},"ISSN":["0004-9417"],"issn-type":[{"value":"0004-9417","type":"print"}],"subject":[],"published":{"date-parts":[[1981,9,1]]}}}