{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:07:06Z","timestamp":1786115226603,"version":"build-2736575974"},"reference-count":25,"publisher":"CSIRO Publishing","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100023240","name":"New Zealand Pharmacy Education and Research Foundation","doi-asserted-by":"publisher","award":["Grant 326"],"award-info":[{"award-number":["Grant 326"]}],"id":[{"id":"10.13039\/501100023240","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>New Zealand has maintained a low HIV prevalence through comprehensive screening, treatment, and prevention programmes. However, challenges remain with access to pre-exposure prophylaxis (PrEP) for at-risk populations, particularly men who have sex with men (MSM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to evaluate the implementation and outcomes of a community-based project that expanded PrEP access via a Standing Order authorising peer HIV testers and pharmacists to initiate short-term PrEP prior to general practitioner follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Conducted between May 2020 and July 2021, the project involved collaboration between a community-based HIV support organisation, a general medical practice, and a community pharmacy in Auckland. Participants received an initial 10-day PrEP supply following a negative HIV rapid test and screening for contraindications, with follow-up laboratory testing and prescriptions managed by the practitioner and pharmacist team.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-six clients enrolled (aged 22\u201360 years). Most identified as European (n = 16), Asian (n = 10), or M\u0101ori (n = 8). No participants seroconverted to HIV during the study. Six sexually transmitted infections were diagnosed and treated. A degree of hepatocellular damage was reported in one participant, and mild but transient liver enzyme elevation occurred in a further five participants. No renal toxicity was recorded. The mean duration of PrEP use was approximately 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This project demonstrated that community-initiated PrEP under a Standing Order can be a safe, acceptable, and effective method for expanding HIV prevention services amongst MSM. This model supports future policy directions to broaden PrEP access through trained pharmacists and community channels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1071\/hc26104","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:51:56Z","timestamp":1784829116000},"source":"Crossref","is-referenced-by-count":0,"title":["Enhancing access to HIV pre-exposure prophylaxis (PrEP) through a community-based project in New Zealand"],"prefix":"10.1071","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3841-0334","authenticated-orcid":true,"given":"Charon","family":"Lessing","sequence":"first","affiliation":[{"name":"School of Community and Public Health, Faculty of Health and Environmental Sciences A , , , .","place":["Auckland, New Zealand"]},{"name":"Auckland University of Technology A , , , .","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Fisher","sequence":"additional","affiliation":[{"name":"Body Positive Inc. Victoria Street West B , , .","place":["Auckland 1142, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Hillebrand","sequence":"additional","affiliation":[{"name":"Independent researchers C , , .","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robbie","family":"Hannon","sequence":"additional","affiliation":[{"name":"Independent researchers C , , .","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"2026080521370129400_R1"},{"key":"2026080521370129400_R2"},{"key":"2026080521370129400_R3"},{"key":"2026080521370129400_R4"},{"key":"2026080521370129400_R5"},{"key":"2026080521370129400_R6"},{"issue":"1426","key":"2026080521370129400_R7","first-page":"8","article-title":"HIV prevention today: with coordinated action, we can end transmission.","volume":"128","author":"Saxton","year":"2015","journal-title":"N Z Med J"},{"issue":"1","key":"2026080521370129400_R8","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1071\/SH18058","article-title":"Enumerating the population eligible for funded HIV pre-exposure prophylaxis (PrEP) in New Zealand.","volume":"16","author":"Saxton","year":"2019","journal-title":"Sex Health"},{"key":"2026080521370129400_R9","unstructured":"Ministry of Health. HIV Monitoring Report: Measuring progress against the National HIV Action Plan for Aotearoa New Zealand 2023\u20132030. Report no:. 978-1-991324\u201363\u20134. Wellington: Ministry of Health; 2025."},{"key":"2026080521370129400_R10"},{"key":"2026080521370129400_R11","unstructured":"Royal New Zealand College of General Practitioners. The Future of Primary Care: Briefing to the Incoming Minister of Health. Briefing Paper. Wellington, New Zealand: RNZCGP; 2022."},{"issue":"1","key":"2026080521370129400_R12","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-023-00729-6","article-title":"Pre-exposure prophylaxis (PrEP) for HIV prevention among people who inject drugs: a global mapping of service delivery.","volume":"20","author":"Shaw","year":"2023","journal-title":"Harm Reduct J"},{"issue":"10","key":"2026080521370129400_R13","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1111\/hiv.13149","article-title":"The success of HIV combination prevention: The Dean Street model.","volume":"22","author":"Girometti","year":"2021","journal-title":"HIV Med"},{"key":"2026080521370129400_R14","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100263","article-title":"HIV diagnoses continue to fall at 56 Dean Street.","volume":"19","author":"Whitlock","year":"2020","journal-title":"EClinicalMedicine"},{"key":"2026080521370129400_R15"},{"key":"2026080521370129400_R16"},{"key":"2026080521370129400_R17"},{"key":"2026080521370129400_R18","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2147\/HIV.S216024","article-title":"Pre-Exposure Prophylaxis (PrEP) in the Prevention of HIV: Strategies, Target Populations and Upcoming Treatments.","volume":"12","author":"\u00d6zdener-Poyraz","year":"2020","journal-title":"HIV\/AIDS - Research & Palliative Care"},{"issue":"41","key":"2026080521370129400_R19","doi-asserted-by":"publisher","first-page":"E1374","DOI":"10.1503\/cmaj.250511","article-title":"Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update.","volume":"197","author":"Tan","year":"2025","journal-title":"CMAJ"},{"issue":"3","key":"2026080521370129400_R20","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s11904-024-00696-y","article-title":"Getting HIV Pre-exposure Prophylaxis (PrEP) into Private Pharmacies: Global Delivery Models and Research Directions.","volume":"21","author":"Roche","year":"2024","journal-title":"Curr HIV\/AIDS Rep"},{"key":"2026080521370129400_R21"},{"key":"2026080521370129400_R22"},{"key":"2026080521370129400_R23"},{"issue":"5","key":"2026080521370129400_R24","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1097\/QAD.0000000000001385","article-title":"Defining the HIV pre-exposure prophylaxis care continuum.","volume":"31","author":"Nunn","year":"2017","journal-title":"AIDS"},{"issue":"8","key":"2026080521370129400_R25","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1136\/sextrans-2021-055277","article-title":"Complex PrEP: the factors requiring consultant-led review of PrEP users.","volume":"98","author":"Tittle","year":"2022","journal-title":"Sex Transm Infect"}],"container-title":["Journal of Primary Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/hc\/article-pdf\/doi\/10.1071\/HC26104\/1947622\/hc26104.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/hc\/article-pdf\/doi\/10.1071\/HC26104\/1947622\/hc26104.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T01:37:08Z","timestamp":1785980228000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/hc\/article\/doi\/10.1071\/HC26104\/274491\/Enhancing-access-to-HIV-pre-exposure-prophylaxis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,24]]},"references-count":25,"URL":"https:\/\/doi.org\/10.1071\/hc26104","relation":{},"ISSN":["1172-6156"],"issn-type":[{"value":"1172-6156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,24]]}}}