{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:06:09Z","timestamp":1784696769171,"version":"3.55.0"},"reference-count":19,"publisher":"CSIRO Publishing","issue":"3","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":4594,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,23]]},"abstract":"<jats:p>Aim: To review the epidemiology of invasive meningococcal disease in NSW for the period 1991\u20132011, in particular since the introduction of the meningococcal C vaccination program in 2003. Methods: We undertook a descriptive analysis of NSW notifications of invasive meningococcal disease for the period 2003\u20132011, and explored long-term changes in the epidemiology of invasive meningococcal disease over the period 1991\u20132011. Results: In the period 2003\u20132011, there were 1009 notifications of invasive meningococcal disease in NSW, an average annual rate of 1.6 per 100 000 population. Notification rates were highest in the 0\u20134 and 15\u201319-year age groups (8.5 and 3.6 per 100 000 population respectively). In the period 1991\u20132011, invasive meningococcal disease notifications increased between 1991 and 2000, peaking at 3.8 notifications per 100 000 population in 2000. Notifications have decreased since that time to 1.0 per 100 000 population in 2011, most markedly for serogroup C disease since the introduction of the meningococcal C vaccination program in 2003. Meningococcal C notifications reduced from 54 in 2002 (0.8 per 100 000 population) to two in 2011 (0.03 per 100 000 population). Meningococcal C deaths have also decreased, from nine in 2002 to zero in 2011. The greatest reduction in meningococcal C notifications has been in those aged 1\u201319 years, the target group for the vaccination program. Meningococcal B notifications have also decreased over the study period, however serogroup B remains the predominant serogroup for invasive meningococcal disease in NSW. Conclusion: Notification rates of invasive meningococcal disease have decreased in NSW since 2000. Rates of serogroup C disease have decreased since the introduction of the meningococcal C vaccination program in 2003. Most of the burden of invasive meningococcal disease in NSW is now due to serogroup B disease.<\/jats:p>","DOI":"10.1071\/nb12121","type":"journal-article","created":{"date-parts":[[2013,12,22]],"date-time":"2013-12-22T20:14:27Z","timestamp":1387743267000},"page":"119-124","source":"Crossref","is-referenced-by-count":0,"title":["Meningococcal disease in NSW, 1991\u20132011: trends in relation to meningococcal C vaccination"],"prefix":"10.1071","volume":"24","author":[{"given":"Erin","family":"Passmore","sequence":"first","affiliation":[{"name":"ANSW Public Health Officer Training Program, NSW Ministry of Health"},{"name":"BSchool of Public Health and Community Medicine, The University of New South Wales"},{"name":"ECorresponding author. Email: epass@doh.health.nsw.gov.au"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Ferson","sequence":"additional","affiliation":[{"name":"BSchool of Public Health and Community Medicine, The University of New South Wales"},{"name":"CPublic Health Unit, South Eastern Sydney Local Health District"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Tobin","sequence":"additional","affiliation":[{"name":"DHealth Protection NSW"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[2013,12,23]]},"reference":[{"issue":"2","key":"2026072200412547300_R1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.33321\/cdi.2003-27-29","article-title":"Introduction of the National Meningococcal C Vaccination Program.","volume":"27","author":"Cohen","year":"2003","journal-title":"Commun Dis Intell"},{"issue":"10","key":"2026072200412547300_R2","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1071\/NB10045","article-title":"NSW Annual Immunisation Coverage Report, 2009.","volume":"21","author":"Hull","year":"2010","journal-title":"N S W Public Health Bull"},{"key":"2026072200412547300_R3"},{"issue":"50","key":"2026072200412547300_R4","doi-asserted-by":"publisher","first-page":"6974","DOI":"10.1016\/j.vaccine.2009.09.082","article-title":"Kinetics of antibody responses after primary immunization with meningococcal serogroup C conjugate vaccine or secondary immunization with either conjugate or polysaccharide vaccine in adults.","volume":"27","author":"de Voer","year":"2009","journal-title":"Vaccine"},{"issue":"21","key":"2026072200412547300_R5","first-page":"322","article-title":"Meningococcal disease in New South Wales.","volume":"21","author":"McAnulty","year":"1997","journal-title":"Commun Dis Intell"},{"issue":"3","key":"2026072200412547300_R6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1071\/NB04011","article-title":"Meningococcal disease in New South Wales, 1991\u20132002.","volume":"15","author":"Hogan","year":"2004","journal-title":"N S W Public Health Bull"},{"issue":"Suppl","key":"2026072200412547300_R7","first-page":"S1","article-title":"Vaccine preventable diseases in Australia, 2005 to 2007.","volume":"34","author":"Chiu","year":"2010","journal-title":"Commun Dis Intell"},{"issue":"3","key":"2026072200412547300_R8","doi-asserted-by":"crossref","first-page":"E251","DOI":"10.33321\/cdi.2012.36.19","article-title":"Annual report of the Australian Meningococcal Surveillance Program.","volume":"36","author":"Lahra","year":"2012","journal-title":"Commun Dis Intell"},{"issue":"1","key":"2026072200412547300_R9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.33321\/cdi.2012.36.1","article-title":"Australia's notifiable diseases status, 2010: Annual report of the National Notifiable Diseases Surveillance System - Results: Other bacterial infections.","volume":"36","author":"NNDSS Annual Report Writing Group","year":"2012","journal-title":"Commun Dis Intell"},{"key":"2026072200412547300_R10","unstructured":"Australian Government Department of Health and Ageing. National Notifiable Diseases Surveillance System. Disease notification rates, Australia, 1991\u20132012. Available at: http:\/\/www9.health.gov.au\/cda\/source\/rpt_2.cfm?RequestTimeout=500 (Cited 13 November 2013)."},{"issue":"5","key":"2026072200412547300_R11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/BF03405245","article-title":"Impact of routine immunization using meningococcal C conjugate vaccine on invasive meningococcal disease in British Columbia.","volume":"99","author":"Siu","year":"2008","journal-title":"Can J Public Health"},{"issue":"9","key":"2026072200412547300_R12","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1099\/0022-1317-51-9-717","article-title":"Impact of meningococcal C conjugate vaccine in the UK.","volume":"51","author":"Balmer","year":"2002","journal-title":"J Med Microbiol"},{"issue":"32","key":"2026072200412547300_R13","doi-asserted-by":"publisher","first-page":"4097","DOI":"10.1016\/j.vaccine.2005.03.045","article-title":"Mateo Sd. Impact and effectiveness of meningococcal C conjugate vaccine following its introduction in Spain.","volume":"23","author":"Larrauri","year":"2005","journal-title":"Vaccine"},{"issue":"9854","key":"2026072200412547300_R14","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1016\/S0140-6736(12)61187-8","article-title":"Effect of vaccines on bacterial meningitis worldwide.","volume":"380","author":"McIntyre","year":"2012","journal-title":"Lancet"},{"issue":"10","key":"2026072200412547300_R15","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/S1473-3099(06)70584-9","article-title":"No evidence for capsule replacement following mass immunisation with meningococcal serogroup C conjugate vaccines in England and Wales.","volume":"6","author":"Trotter","year":"2006","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 2","key":"2026072200412547300_R16","doi-asserted-by":"publisher","first-page":"S54","DOI":"10.1086\/648966","article-title":"Review of meningococcal group B vaccines.","volume":"50","author":"Granoff","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"9","key":"2026072200412547300_R17","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/S1474-4422(12)70180-1","article-title":"Outcomes of invasive meningococcal serogroup B disease in children and adolescents (MOSAIC): a case-control study.","volume":"11","author":"Viner","year":"2012","journal-title":"Lancet Neurol"},{"issue":"3","key":"2026072200412547300_R18","doi-asserted-by":"publisher","first-page":"e502","DOI":"10.1542\/peds.2008-0581","article-title":"Outcomes of meningococcal disease in adolescence: prospective, matched-cohort study.","volume":"123","author":"Borg","year":"2009","journal-title":"Pediatrics"},{"issue":"1","key":"2026072200412547300_R19","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/pubmed\/fdp075","article-title":"Invasive meningococcal disease: improving management through structured review of cases in the Hunter New England area","volume":"32","author":"Guimont","year":"2010","journal-title":"Aust J Public Health"}],"container-title":["New South Wales Public Health Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/pu\/article-pdf\/24\/3\/119\/1945843\/nb12121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/pu\/article-pdf\/24\/3\/119\/1945843\/nb12121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:41:46Z","timestamp":1784695306000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/pu\/article\/24\/3\/119\/275283\/Meningococcal-disease-in-NSW-1991-2011-trends-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,23]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,12,23]]}},"URL":"https:\/\/doi.org\/10.1071\/nb12121","relation":{},"ISSN":["1034-7674","1444-8262"],"issn-type":[{"value":"1034-7674","type":"print"},{"value":"1444-8262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,23]]}}}