{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T23:11:41Z","timestamp":1789081901685,"version":"build-2803163510"},"reference-count":22,"publisher":"CSIRO Publishing","issue":"3","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021952","name":"MTPConnect","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021952","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021096","name":"George Institute for Global Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021096","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001773","name":"University of New South Wales","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001773","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009287","name":"NSW Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009287","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,24]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Recruitment to medical research projects is challenging. We evaluated the feasibility of supporting recruitment of human participants to Australian research studies using a national disease-agnostic research register.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We undertook a quantitative longitudinal evaluation of participant enrolment and researcher utilisation of \u2018Join Us\u2019, a disease-agnostic research register, from its inception on 12 August 2020 to 28 July 2025. Participants were Australian adults (aged \u226518 years) and Australian research studies recruiting human participants. The main outcome measures included the numbers and demographics of community participants in \u2018Join Us\u2019, and the numbers and characteristics of the research studies supported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\u2018Join Us\u2019 was established in 2020 with input from &amp;gt;50 organisations spanning consumer, academic, health service and disease interest groups, and including every state and territory. As of 28 July 2025, there were 10,276 participants enrolled, with a mean age of 51 years (range 18\u201395 years), 71% women, 21% reporting a non-English language spoken in the home and 3% identifying as Aboriginal or Torres Strait Islander. The health issues most frequently reported by participants were mental health problems (40%) and cardiovascular disease (36%), with 11% of participants reporting no health problems. The register has issued &amp;gt;67,000 invitations to participate in 143 research studies conducted by researchers based in six states and territories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The \u2018Join Us\u2019 vanguard phase has demonstrated the feasibility of implementing a disease-agnostic digital research register and its potential for supporting recruitment to diverse studies nationwide. Scaling the register has significant potential to satisfy both community calls for better opportunities to participate in research and researcher needs for enhanced recruitment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1071\/pu25093","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T22:50:30Z","timestamp":1789080630000},"source":"Crossref","is-referenced-by-count":0,"title":["\u2018Join Us\u2019: the vanguard phase of a disease-agnostic Australian research register"],"prefix":"10.1071","volume":"36","author":[{"given":"Bruce","family":"Neal","sequence":"first","affiliation":[{"name":"The George Institute for Global Health A , , , .","place":["Sydney, NSW, Australia"]},{"name":"Faculty of Medicine and Health B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"UNSW Sydney B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"School of Public Health C , , , .","place":["London, United Kingdom"]},{"name":"Imperial College London C , , , .","place":["London, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Smith","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health A , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Arnott","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health A , , , .","place":["Sydney, NSW, Australia"]},{"name":"Faculty of Medicine and Health B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"UNSW Sydney B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"Department of Cardiology D , , , , .","place":["Sydney, NSW, Australia"]},{"name":"Royal Prince Alfred Hospital D , , , , .","place":["Sydney, NSW, Australia"]},{"name":"Department of Cardiology E , , , , .","place":["Sydney, NSW, Australia"]},{"name":"St Vincent\u2019s Hospital E , , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louisa Ruth","family":"Jorm","sequence":"additional","affiliation":[{"name":"Centre for Big Data Research in Health F , , , , .","place":["Sydney, NSW, Australia"]},{"name":"UNSW Sydney F , , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Neale","sequence":"additional","affiliation":[{"name":"QIMR Berghofer G , , , .","place":["Brisbane, Qld, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Brown","sequence":"additional","affiliation":[{"name":"Health Consumers NSW H , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Stewart","sequence":"additional","affiliation":[{"name":"Independent Researcher I , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Houston","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health A , , , .","place":["Sydney, NSW, Australia"]},{"name":"Faculty of Medicine and Health B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"UNSW Sydney B , , , , .","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Monaghan","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health A , , , .","place":["Sydney, NSW, Australia"]},{"name":"Faculty of Medicine and Health B , , , , .","place":["Sydney, NSW, Australia"]},{"name":"UNSW Sydney B , , , , .","place":["Sydney, NSW, 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Scoping and analysis of recruitment and retention in Australian clinical trials. Department of Health. Australia; 2016. Available at https:\/\/docest.com\/doc\/633314\/scoping-and-analysis-of-recruitment-and-retention-in-australian-clinical-trials [cited 19 August 2025]"},{"key":"2026091018502566500_R8"},{"key":"2026091018502566500_R9"},{"key":"2026091018502566500_R10"},{"issue":"12","key":"2026091018502566500_R11","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-031705","article-title":"Cohort profile: HealthWise Wales. 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