{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T08:06:06Z","timestamp":1789373166378,"version":"build-2803163510"},"reference-count":27,"publisher":"CSIRO Publishing","issue":"3","license":[{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1025142, GNT1043134, GNT1120431"],"award-info":[{"award-number":["GNT1025142, GNT1043134, GNT1120431"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian Medical Research Futures Fund","award":["MRF1200503"],"award-info":[{"award-number":["MRF1200503"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,24]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Understanding patterns of cancer care is important for improving patient safety and reducing inequity. Linked administrative datasets offer a cost-efficient alternative to medical chart abstraction, but the information may not be as comprehensive and accurate. Our aim was to determine the validity of using linked administrative data to identify ovarian cancer primary treatment in Australia, using data from medical charts for comparison.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data from the Ovarian cancer Prognosis And Lifestyle study, a national prospective cohort study including women diagnosed with ovarian cancer from 2012 to 2015. Treatment information collected via medical records was used as the reference standard. Linked administrative data were obtained from national (Medicare Benefits Schedule, Pharmaceutical Benefits Scheme) and state\/territory (hospital admitted patient data collections) data linkage units. The data were partitioned into training (60%, n = 413) and validation (40%, n = 271) datasets. Initial definitions were developed and further refined using the training set and based on clinical advice. The final definitions were assessed using the validation set. Sensitivity, specificity, negative predictive value, positive predictive value and kappa were calculated for receipt of treatment, whereas agreement was assessed for dates and continuous measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sensitivity and specificity were high for receipt of chemotherapy (99%, 100%), cytoreductive surgery (97%, 100%), platinum-based chemotherapy (97%, 100%), taxane-based chemotherapy (98%, 88%), intra-peritoneal chemotherapy (93%, 99%) and whether chemotherapy was given in the adjuvant setting (100%, 90%). Agreement for treatment dates was high for surgery (exact agreement 90%, 97% \u00b17 days) and first chemotherapy (85%, 96% \u00b17 days). Agreement was moderately high for end of primary chemotherapy (72%, 82% \u00b17 days), number of chemotherapy cycles (65%, 89% \u00b11 cycle) and chemotherapy regimen (86%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Linked administrative data can provide accurate information on core aspects of ovarian cancer treatment when there are barriers to accessing patient medical records.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1071\/pu25097","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T07:06:36Z","timestamp":1789369596000},"source":"Crossref","is-referenced-by-count":0,"title":["Using administrative health data to ascertain ovarian cancer treatment information in Australia: a validation against medical records"],"prefix":"10.1071","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4359-3582","authenticated-orcid":true,"given":"Kate","family":"Gersekowski","sequence":"first","affiliation":[{"name":"Population Health Program A , , , , .","place":["Brisbane, Qld, Australia"]},{"name":"QIMR Berghofer A , , , , .","place":["Brisbane, Qld, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7924-1357","authenticated-orcid":true,"given":"Jim","family":"Codde","sequence":"additional","affiliation":[{"name":"Institute for Health Research, The University of Notre Dame Australia B , , , .","place":["Fremantle, WA, Australia"]},{"name":"Division of Obstetrics and Gynaecology C , , , , .","place":["Perth, WA, Australia"]},{"name":"Medical School, University of Western Australia C , , , , .","place":["Perth, WA, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4860-9232","authenticated-orcid":true,"given":"Paul A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynaecology C , , , , .","place":["Perth, WA, Australia"]},{"name":"Medical School, University of Western Australia C , , , , .","place":["Perth, WA, Australia"]},{"name":"Department of Gynaecological Oncology D , , , , .","place":["Subiaco, WA, Australia"]},{"name":"King Edward Memorial Hospital D , , , , .","place":["Subiaco, WA, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology E , , , , .","place":["Melbourne, Vic, Australia"]},{"name":"Western Health, Sunshine Hospital E , , , , .","place":["Melbourne, Vic, Australia"]},{"name":"Department of Obstetrics, Gynaecology and Newborn Health, Mercy Hospital for Women F , , , , .","place":["Heidelberg, Vic, Australia"]},{"name":"University of Melbourne F , , , , .","place":["Heidelberg, Vic, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan J.","family":"Jordan","sequence":"additional","affiliation":[{"name":"School of Public Health G , , , , .","place":["Brisbane, Qld, Australia"]},{"name":"University of Queensland G , , , , .","place":["Brisbane, Qld, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope M.","family":"Webb","sequence":"additional","affiliation":[{"name":"Population Health Program A , , , , .","place":["Brisbane, Qld, Australia"]},{"name":"QIMR Berghofer A , , , , .","place":["Brisbane, Qld, Australia"]},{"name":"School of Public Health G , , , , .","place":["Brisbane, Qld, Australia"]},{"name":"University of Queensland G , , , , .","place":["Brisbane, Qld, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"2026091403063060200_R1","unstructured":"Australian Institute of Health and Welfare. Cancer data in Australia. Canberra: AIHW; 2023. Available at https:\/\/www.aihw.gov.au\/reports\/cancer\/cancer-data-in-australia\/contents\/overview [cited 12 August 2024]"},{"key":"2026091403063060200_R2"},{"issue":"1","key":"2026091403063060200_R3","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1093\/annonc\/mdv500","article-title":"Early initiation of chemotherapy following complete resection of advanced ovarian cancer associated with improved survival: NRG Oncology\/Gynecologic Oncology Group study.","volume":"27","author":"Tewari","year":"2016","journal-title":"Ann Oncol"},{"issue":"2","key":"2026091403063060200_R4","doi-asserted-by":"publisher","first-page":"114","DOI":"10.36469\/jheor.2021.29145","article-title":"Real-world treatment patterns, survival, and costs for ovarian cancer in Canada: a retrospective cohort study using provincial administrative data.","volume":"8","author":"Hurry","year":"2021","journal-title":"J Health Econ Outcomes Res"},{"issue":"4","key":"2026091403063060200_R5","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1111\/jep.12183","article-title":"Treatment patterns among colorectal cancer patients in South Australia: a demonstration of the utility of population-based data linkage.","volume":"20","author":"Beckmann","year":"2014","journal-title":"J Eval Clin Pract"},{"issue":"1","key":"2026091403063060200_R6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1245\/s10434-023-14375-6","article-title":"Treatment patterns and outcomes in pancreatic cancer: a comparative analysis of Ontario and the USA.","volume":"31","author":"Saadat","year":"2024","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"2026091403063060200_R7","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1158\/1055-9965.EPI-11-1075","article-title":"Validity of eight integrated healthcare delivery organizations\u2019 administrative clinical data to capture breast cancer chemotherapy exposure.","volume":"21","author":"Delate","year":"2012","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"1","key":"2026091403063060200_R8","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-12-387","article-title":"Using administrative health data to describe colorectal and lung cancer care in New South Wales, Australia: a validation study.","volume":"12","author":"Goldsbury","year":"2012","journal-title":"BMC Health Serv Res"},{"key":"2026091403063060200_R9","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-11-253","article-title":"Using linked routinely collected health data to describe prostate cancer treatment in New South Wales, Australia: a validation study.","volume":"11","author":"Goldsbury","year":"2011","journal-title":"BMC Health Serv Res"},{"issue":"5","key":"2026091403063060200_R10","doi-asserted-by":"publisher","DOI":"10.17061\/phrp2751744","article-title":"Retrospective comparison of Australia\u2019s Pharmaceutical Benefits Scheme claims data with prescription data in HER2-positive early breast cancer patients, 2008-2012.","volume":"27","author":"Harris","year":"2017","journal-title":"Public Health Res Pract"},{"issue":"2","key":"2026091403063060200_R11","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/pds.4616","article-title":"Validation studies of claims data in the Asia-Pacific region: a comprehensive review.","volume":"28","author":"Koram","year":"2019","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"1","key":"2026091403063060200_R12","doi-asserted-by":"publisher","DOI":"10.13063\/2327-9214.1208","article-title":"A validation study of administrative claims data to measure ovarian cancer recurrence and secondary debulking surgery.","volume":"4","author":"Livaudais-Toman","year":"2016","journal-title":"EGEMS (Wash DC)"},{"issue":"1","key":"2026091403063060200_R13","doi-asserted-by":"publisher","DOI":"10.17061\/phrp3012004","article-title":"Capture of systemic anticancer therapy use by routinely collected health datasets.","volume":"30","author":"Tervonen","year":"2020","journal-title":"Public Health Res Pract"},{"issue":"1","key":"2026091403063060200_R14","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9218595","article-title":"Validity of administrative databases in comparison to medical charts for breast cancer treatment data.","volume":"2018","author":"Weerasinghe","year":"2018","journal-title":"J Cancer Epidemiol"},{"issue":"8","key":"2026091403063060200_R15","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.jclinepi.2010.10.006","article-title":"Development and use of reporting guidelines for assessing the quality of validation studies of health administrative data.","volume":"64","author":"Benchimol","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"2026091403063060200_R16"},{"key":"2026091403063060200_R17","unstructured":"Australian Government Department of Health and Aged Care. Efficient funding of chemotherapy program 2024. Available at https:\/\/www.pbs.gov.au\/info\/browse\/section-100\/chemotherapy [cited 22 June 2026]"},{"issue":"12","key":"2026091403063060200_R18","doi-asserted-by":"publisher","first-page":"3361","DOI":"10.1002\/ijc.33155","article-title":"A healthy lifestyle and survival among women with ovarian cancer.","volume":"147","author":"Hansen","year":"2020","journal-title":"Int J Cancer"},{"key":"2026091403063060200_R19"},{"key":"2026091403063060200_R20"},{"key":"2026091403063060200_R21"},{"key":"2026091403063060200_R22"},{"issue":"1","key":"2026091403063060200_R23","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data.","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"6","key":"2026091403063060200_R24","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/ajo.12665","article-title":"The shift toward neo-adjuvant chemotherapy and interval debulking surgery for management of advanced ovarian and related cancers in a population-based setting: impact on clinical outcomes.","volume":"57","author":"Nicklin","year":"2017","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"1","key":"2026091403063060200_R25","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.ygyno.2020.04.706","article-title":"Evaluating the impact of dose reductions and delays on progression-free survival in women with ovarian cancer treated with either three-weekly or dose-dense carboplatin and paclitaxel regimens in the national prospective OPAL cohort study.","volume":"158","author":"Sivakumaran","year":"2020","journal-title":"Gynecol Oncol"},{"key":"2026091403063060200_R26","unstructured":"Australian Government Department of Health and Aged Care. Factsheet: MBS chemotherapeutic procedures; 2020. Available at https:\/\/www.mbsonline.gov.au\/internet\/mbsonline\/publishing.nsf\/Content\/Factsheet-Chemotherapy-Nov20 [cited 12 August 2024]"},{"issue":"1","key":"2026091403063060200_R27","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1071\/AH23185","article-title":"The burdensome logistics of data linkage in Australia \u2013 the example of a national registry for congenital heart disease.","volume":"48","author":"Lloyd","year":"2024","journal-title":"Aust Health Rev"}],"container-title":["Public Health Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/pu\/article-pdf\/doi\/10.1071\/PU25097\/1953957\/pu25097.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/pu\/article-pdf\/doi\/10.1071\/PU25097\/1953957\/pu25097.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T07:07:37Z","timestamp":1789369657000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/pu\/article\/36\/3\/PU25097\/272649\/Using-administrative-health-data-to-ascertain"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,14]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9,24]]}},"URL":"https:\/\/doi.org\/10.1071\/pu25097","relation":{},"ISSN":["2204-2091"],"issn-type":[{"value":"2204-2091","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,14]]},"article-number":"PU25097"}}