{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:47:42Z","timestamp":1761709662095,"version":"build-2065373602"},"reference-count":86,"publisher":"CSIRO Publishing","issue":"3","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":6649,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,3,19]]},"abstract":"<jats:p>The pineal gland, through its hormone melatonin, influences the function of the hypothalamic\u2013pituitary\u2013gonadal axis. Tachykinins are bioactive peptides whose presence has been demonstrated in the pineal gland, hypothalamus, anterior pituitary gland and the gonads, in addition to other central and peripheral structures. Tachykinins have been demonstrated to influence the function of the hypothalamic\u2013pituitary\u2013gonadal axis, acting as paracrine factors at each of these levels. In the present review, we examine the available evidence supporting a role for melatonin in the regulation of reproductive functions, the possible role of tachykinins in pineal function and the possible interactions between melatonin and tachykinins in the hypothalamic\u2013pituitary\u2013gonadal axis. Evidence is presented showing that melatonin, given to pregnant rats, influences the developmental pattern of tachykinins in the hypothalamus and the anterior pituitary gland of the offspring during postnatal life. In the gonads, the effects of melatonin on the tachykinin developmental pattern were rather modest. In particular, in the present review, we have included a summary of our own work performed in the past few years on the effect of melatonin on tachykinin levels in the hypothalamic\u2013pituitary\u2013gonadal axis.<\/jats:p>","DOI":"10.1071\/rd06140","type":"journal-article","created":{"date-parts":[[2007,3,18]],"date-time":"2007-03-18T21:04:14Z","timestamp":1174251854000},"page":"443-451","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal melatonin and its interaction with tachykinins in the hypothalamic\u2013pituitary\u2013gonadal axis"],"prefix":"10.1071","volume":"19","author":[{"given":"B. D\u00edaz","family":"L\u00f3pez","sequence":"first","affiliation":[{"name":"ADepartamento de Biolog\u00eda Funcional, \u00c1rea Fisiolog\u00eda, Facultad de Medicina, Universidad de Oviedo, C\/ Juli\u00e1n Claver\u00eda no. 6, 33006 Oviedo, Spain."},{"name":"CCorresponding author. Email: beatrizd@uniovi.es"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Debeljuk","sequence":"additional","affiliation":[{"name":"BSchool of Allied Health, Section of Anatomy and Physiology, College of Applied Sciences and Arts, Southern Illinois University, Carbondale, IL 62901-6615, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"67","published-online":{"date-parts":[[2007,3,14]]},"reference":[{"key":"2025102818353216400_R1"},{"key":"2025102818353216400_R2"},{"key":"2025102818353216400_R3"},{"key":"2025102818353216400_R4"},{"key":"2025102818353216400_R5"},{"key":"2025102818353216400_R6"},{"key":"2025102818353216400_R7"},{"key":"2025102818353216400_R8"},{"key":"2025102818353216400_R9"},{"key":"2025102818353216400_R10"},{"key":"2025102818353216400_R11"},{"key":"2025102818353216400_R12"},{"key":"2025102818353216400_R13"},{"key":"2025102818353216400_R14"},{"key":"2025102818353216400_R15"},{"key":"2025102818353216400_R16"},{"key":"2025102818353216400_R17"},{"key":"2025102818353216400_R18"},{"key":"2025102818353216400_R19"},{"key":"2025102818353216400_R20"},{"key":"2025102818353216400_R21"},{"key":"2025102818353216400_R22"},{"key":"2025102818353216400_R23"},{"key":"2025102818353216400_R24"},{"key":"2025102818353216400_R25"},{"key":"2025102818353216400_R26"},{"key":"2025102818353216400_R27"},{"key":"2025102818353216400_R28"},{"key":"2025102818353216400_R29"},{"key":"2025102818353216400_R30"},{"key":"2025102818353216400_R31"},{"key":"2025102818353216400_R32"},{"key":"2025102818353216400_R33"},{"key":"2025102818353216400_R34"},{"key":"2025102818353216400_R35"},{"key":"2025102818353216400_R36"},{"key":"2025102818353216400_R37"},{"key":"2025102818353216400_R38"},{"key":"2025102818353216400_R39"},{"key":"2025102818353216400_R40"},{"key":"2025102818353216400_R41"},{"key":"2025102818353216400_R42"},{"key":"2025102818353216400_R43"},{"key":"2025102818353216400_R44"},{"key":"2025102818353216400_R45"},{"key":"2025102818353216400_R46"},{"key":"2025102818353216400_R47"},{"key":"2025102818353216400_R48"},{"key":"2025102818353216400_R49"},{"key":"2025102818353216400_R50"},{"key":"2025102818353216400_R51"},{"key":"2025102818353216400_R52"},{"key":"2025102818353216400_R53"},{"key":"2025102818353216400_R54"},{"key":"2025102818353216400_R55"},{"key":"2025102818353216400_R56"},{"key":"2025102818353216400_R57"},{"key":"2025102818353216400_R58"},{"key":"2025102818353216400_R59"},{"key":"2025102818353216400_R60"},{"key":"2025102818353216400_R61"},{"key":"2025102818353216400_R62"},{"key":"2025102818353216400_R63"},{"key":"2025102818353216400_R64"},{"key":"2025102818353216400_R65"},{"key":"2025102818353216400_R66"},{"key":"2025102818353216400_R67"},{"key":"2025102818353216400_R68"},{"key":"2025102818353216400_R69"},{"key":"2025102818353216400_R70"},{"key":"2025102818353216400_R71"},{"key":"2025102818353216400_R72"},{"key":"2025102818353216400_R73"},{"key":"2025102818353216400_R74"},{"key":"2025102818353216400_R75"},{"key":"2025102818353216400_R76"},{"key":"2025102818353216400_R77"},{"key":"2025102818353216400_R78"},{"key":"2025102818353216400_R79"},{"key":"2025102818353216400_R80"},{"key":"2025102818353216400_R81"},{"key":"2025102818353216400_R82"},{"key":"2025102818353216400_R83"},{"key":"2025102818353216400_R84"},{"key":"2025102818353216400_R85"},{"key":"2025102818353216400_R86"}],"container-title":["Reproduction, Fertility and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/19\/3\/443\/301056\/rd06140.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/19\/3\/443\/301056\/rd06140.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:35:39Z","timestamp":1761690939000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/rd\/article\/19\/3\/443\/48482\/Prenatal-melatonin-and-its-interaction-with"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,14]]},"references-count":86,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3,19]]}},"URL":"https:\/\/doi.org\/10.1071\/rd06140","relation":{},"ISSN":["1031-3613","1448-5990"],"issn-type":[{"type":"print","value":"1031-3613"},{"type":"electronic","value":"1448-5990"}],"subject":[],"published":{"date-parts":[[2007,3,14]]}}}