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One way to achieve this is by using non-surgical methods of sterilisation, which are suitable in the context of this mobile and long-lived species. In this review we consider the benefits of implementing novel mechanisms designed to elicit a state of permanent sterility (including redox cycling to generate oxidative stress in the gonad, random peptide phage display to target non-renewable germ cells and the generation of autoantibodies against proteins essential for conception via covalent modification) compared with that of traditional immunocontraceptive approaches. The need for a better understanding of mare folliculogenesis and conception factors, including maternal recognition of pregnancy, is also reviewed because they hold considerable potential in providing a non-surgical mechanism for sterilisation. In conclusion, the authors contend that non-surgical measures that are single shot and irreversible may provide a sustainable and effective strategy for feral horse control.<\/jats:p>","DOI":"10.1071\/rd16200","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T19:25:13Z","timestamp":1475609113000},"page":"1655-1666","source":"Crossref","is-referenced-by-count":10,"title":["Non-surgical sterilisation methods may offer a sustainable solution to feral horse (Equus caballus) overpopulation"],"prefix":"10.1071","volume":"29","author":[{"given":"Sally Elizabeth","family":"Hall","sequence":"first","affiliation":[{"name":"APriority Research Centre for Reproductive Science, School of Environmental and Life Sciences, Life Sciences Building, University of Newcastle, Callaghan, NSW 2308, Australia."},{"name":"BInvasive Animals Cooperative Research Centre, Building 22, University of Canberra, University Drive South, Bruce, ACT 2617, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Nixon","sequence":"additional","affiliation":[{"name":"APriority Research Centre for Reproductive Science, School of Environmental and Life Sciences, Life Sciences Building, University of Newcastle, Callaghan, NSW 2308, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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