{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T03:44:51Z","timestamp":1767843891282,"version":"3.49.0"},"reference-count":61,"publisher":"CSIRO Publishing","issue":"9","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":3150,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8,14]]},"abstract":"<jats:p>An increasing number of reports suggests a role of hyaluronan (HA) in female reproduction and interest in its application in assisted reproduction is rising. However, there are contrasting data about the effectiveness of adding HA to the embryo-transfer medium on improving pregnancy rates. Using sheep as an experimental model, the studies reported here analysed the impact of HA infusion into the uterus on embryo attachment to uterine luminal epithelium (LE) and expression of selected markers of uterine receptivity. On Day 14 after natural mating (pre-attachment), uterine horns were infused with either (n = 4 each): PBS (control), HA (1 mg mL\u20131), HA + hyaluronidase 2 (Hyal2; 300 IU mL\u20131) or 4-methyl-umbelliferone (HA-synthesis inhibitor; 4MU, 1 mM). HA immunostaining on uterine sections collected on Day 17 was negative in the 4MU group and weak in the HA+Hyal2 group. In contrast to 4MU, which resulted in 100% attachment, HA infusion blocked embryo attachment in all treated animals. This was accompanied by the disappearance of mucin 1 and increased expression of osteopontin and CD44v6 in the LE of uteri with attached embryos. In conclusion, the presence of HA at the embryo\u2013maternal interface during embryo implantation resulted in reduced endometrial receptivity and inhibited the interaction of trophoblasts with the LE, whereas clearance of HA favoured embryo attachment.<\/jats:p>","DOI":"10.1071\/rd16232","type":"journal-article","created":{"date-parts":[[2016,10,10]],"date-time":"2016-10-10T19:34:33Z","timestamp":1476128073000},"page":"1763-1773","source":"Crossref","is-referenced-by-count":8,"title":["Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep"],"prefix":"10.1071","volume":"29","author":[{"given":"Waleed F. A.","family":"Marei","sequence":"first","affiliation":[{"name":"AReproduction Group, Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK."},{"name":"BDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Claire","family":"Wathes","sequence":"additional","affiliation":[{"name":"AReproduction Group, Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kabir A.","family":"Raheem","sequence":"additional","affiliation":[{"name":"AReproduction Group, Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK."},{"name":"CDepartment of Veterinary Surgery and Theriogenology, Michael Okpara University of Agriculture, Umudike 445678, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omnia","family":"Mohey-Elsaeed","sequence":"additional","affiliation":[{"name":"DDepartment of Cytology and Histology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fataneh","family":"Ghafari","sequence":"additional","affiliation":[{"name":"AReproduction Group, Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali A.","family":"Fouladi-Nashta","sequence":"additional","affiliation":[{"name":"AReproduction Group, Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK."},{"name":"ECorresponding author. Email: afouladi@rvc.ac.uk"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"67","published-online":{"date-parts":[[2016,10,11]]},"reference":[{"issue":"3","key":"2025102819290906600_R1","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1097\/00129039-200609000-00012","article-title":"Temporal variation in the distribution of hyaluronic acid, CD44s, and CD44v6 in the human endometrium across the menstrual cycle.","volume":"14","author":"Afify","year":"2006","journal-title":"Appl. Immunohistochem. Mol. Morphol."},{"issue":"2","key":"2025102819290906600_R2","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1095\/BIOLREPROD.112.100016","article-title":"Endometrial receptivity defects and impaired implantation in diabetic NOD mice.","volume":"87","author":"Albaghdadi","year":"2012","journal-title":"Biol. Reprod."},{"issue":"2","key":"2025102819290906600_R3","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1530\/ROR.0.0020084","article-title":"Adhesion molecules in implantation.","volume":"2","author":"Aplin","year":"1997","journal-title":"Rev. Reprod."},{"issue":"6","key":"2025102819290906600_R4","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/S1472-6483(10)61032-2","article-title":"Embryo implantation: the molecular mechanism remains elusive.","volume":"13","author":"Aplin","year":"2006","journal-title":"Reprod. Biomed. Online"},{"key":"2025102819290906600_R5","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/1477-7827-2-48","article-title":"Trophoblast-uterine interactions at implantation.","volume":"2","author":"Aplin","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"key":"2025102819290906600_R6","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1016\/0092-8674(90)90694-A","article-title":"CD44 is the principal cell surface receptor for hyaluronate.","volume":"61","author":"Aruffo","year":"1990","journal-title":"Cell"},{"key":"2025102819290906600_R7","doi-asserted-by":"publisher","first-page":"CD007421","DOI":"10.1002\/14651858.CD007421.PUB3","article-title":"Adherence compounds in embryo transfer media for assisted reproductive technologies.","volume":"2","author":"Bontekoe","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"key":"2025102819290906600_R8","doi-asserted-by":"publisher","first-page":"4(1-9)","DOI":"10.1186\/1477-7827-2-4","article-title":"MUC1: a multifunctional cell surface component of reproductive tissue epithelia.","volume":"2","author":"Brayman","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"7","key":"2025102819290906600_R9","doi-asserted-by":"publisher","first-page":"3002","DOI":"10.2527\/JAS.2013-5882","article-title":"Triennial Reproduction Symposium: deficiencies in the uterine environment and failure to support embryonic development.","volume":"91","author":"Bridges","year":"2013","journal-title":"J. Anim. Sci."},{"issue":"1","key":"2025102819290906600_R10","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1111\/J.1432-0436.1992.TB00500.X","article-title":"Distribution of hyaluronan in the mouse endometrium during the periimplantation period of pregnancy.","volume":"52","author":"Brown","year":"1992","journal-title":"Differentiation"},{"issue":"2","key":"2025102819290906600_R11","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1242\/dev.117.2.483","article-title":"Ontogeny of hyaluronan secretion during early mouse development.","volume":"117","author":"Brown","year":"1993","journal-title":"Development"},{"issue":"Supplement","key":"2025102819290906600_R12","doi-asserted-by":"publisher","first-page":"S434","DOI":"10.1016\/J.FERTNSTERT.2008.07.1185","article-title":"The effect of embryo glue on clinical pregnancy rate in frozen embryo transfers.","volume":"90","author":"Chao","year":"2008","journal-title":"Fertil. Steril."},{"issue":"1","key":"2025102819290906600_R13","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/J.PLACENTA.2008.10.013","article-title":"Murine abortion is associated with enhanced hyaluronan expression and abnormal localization at the fetomaternal interface.","volume":"30","author":"Cordo-Russo","year":"2009","journal-title":"Placenta"},{"issue":"4 Suppl 2","key":"2025102819290906600_R14","first-page":"S13","article-title":"\u201cEmbryo glue\u201d does not seem to improve chances of subsequent pregnancy in refractory in vitro fertilization cases.","volume":"87","author":"Dietterich","year":"2007","journal-title":"Fertil. Steril."},{"key":"2025102819290906600_R15","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1111\/J.1439-0531.2008.01171.X","article-title":"Embryonic and early foetal losses in cattle and other ruminants.","volume":"43","author":"Diskin","year":"2008","journal-title":"Reprod. Domest. Anim."},{"issue":"1\u20133","key":"2025102819290906600_R16","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/S0014-5793(02)03262-3","article-title":"CD44 signaling through focal adhesion kinase and its anti-apoptotic effect.","volume":"528","author":"Fujita","year":"2002","journal-title":"FEBS Lett."},{"issue":"6","key":"2025102819290906600_R17","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1530\/REP.0.1260721","article-title":"Expression and presence of osteopontin and integrins in the bovine oviduct during the oestrous cycle.","volume":"126","author":"Gabler","year":"2003","journal-title":"Reproduction"},{"issue":"21","key":"2025102819290906600_R18","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1016\/J.LFS.2007.02.037","article-title":"The magic glue hyaluronan and its eraser hyaluronidase: a biological overview.","volume":"80","author":"Girish","year":"2007","journal-title":"Life Sci."},{"issue":"2","key":"2025102819290906600_R19","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1530\/REP.0.1240289","article-title":"Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation.","volume":"124","author":"Gray","year":"2002","journal-title":"Reproduction"},{"key":"2025102819290906600_R20","first-page":"39","article-title":"Cellular interactions during implantation in domestic ruminants.","volume":"49","author":"Guillomot","year":"1995","journal-title":"J. Reprod. Fertil. Suppl."},{"issue":"2","key":"2025102819290906600_R21","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S0143-4004(81)80021-5","article-title":"Conceptus attachment in the ewe: an ultrastructural study.","volume":"2","author":"Guillomot","year":"1981","journal-title":"Placenta"},{"issue":"5","key":"2025102819290906600_R22","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1016\/J.FERTNSTERT.2009.10.019","article-title":"Hyaluronan-enriched transfer medium in cleavage-stage frozen\u2013thawed embryo transfers increases implantation rate without improvement of delivery rate.","volume":"94","author":"Hambiliki","year":"2010","journal-title":"Fertil. Steril."},{"issue":"1","key":"2025102819290906600_R23","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/J.FERTNSTERT.2007.05.063","article-title":"Impact of EmbryoGlue as the embryo transfer medium.","volume":"90","author":"Hazlett","year":"2008","journal-title":"Fertil. Steril."},{"issue":"2","key":"2025102819290906600_R24","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1071\/RDV16N1AB137","article-title":"The effect of anti-CD44 on embryo implantation in rabbits.","volume":"16","author":"Illera","year":"2004","journal-title":"Reprod. Fertil. Dev."},{"key":"2025102819290906600_R25"},{"issue":"5","key":"2025102819290906600_R26","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1095\/BIOLREPROD.103.020651","article-title":"Osteopontin: roles in implantation and placentation.","volume":"69","author":"Johnson","year":"2003","journal-title":"Biol. Reprod."},{"issue":"4","key":"2025102819290906600_R27","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1095\/BIOLREPROD61.4.884","article-title":"Ovine osteopontin: I. Cloning and expression of messenger ribonucleic acid in the uterus during the periimplantation period.","volume":"61","author":"Johnson","year":"1999","journal-title":"Biol. Reprod."},{"issue":"5","key":"2025102819290906600_R28","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1095\/BIOLREPROD62.5.1315","article-title":"Progesterone modulation of osteopontin gene expression in the ovine uterus.","volume":"62","author":"Johnson","year":"2000","journal-title":"Biol. Reprod."},{"issue":"3","key":"2025102819290906600_R29","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1095\/BIOLREPROD65.3.820","article-title":"Muc-1, integrin, and osteopontin expression during the implantation cascade in sheep.","volume":"65","author":"Johnson","year":"2001","journal-title":"Biol. Reprod."},{"issue":"1","key":"2025102819290906600_R30","first-page":"219","article-title":"CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis.","volume":"59","author":"Katagiri","year":"1999","journal-title":"Cancer Res."},{"key":"2025102819290906600_R31","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/1477-7827-2-19","article-title":"Immunohistochemical localization of integrin alpha V beta 3 and osteopontin suggests that they do not interact during embryo implantation in ruminants.","volume":"2","author":"Kimmins","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"11","key":"2025102819290906600_R32","doi-asserted-by":"publisher","first-page":"1914","DOI":"10.1016\/J.YEXCR.2009.03.002","article-title":"4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.","volume":"315","author":"Kultti","year":"2009","journal-title":"Exp. Cell Res."},{"issue":"5","key":"2025102819290906600_R33","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1093\/HUMREP\/17.5.1249","article-title":"Combined treatment by pentoxifylline and tocopherol for recipient women with a thin endometrium enrolled in an oocyte donation programme.","volume":"17","author":"L\u00e9d\u00e9e-Bataille","year":"2002","journal-title":"Hum. Reprod."},{"issue":"3","key":"2025102819290906600_R34","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/J.FERTNSTERT.2011.07.1095","article-title":"Assessment of endometrial receptivity.","volume":"96","author":"Lessey","year":"2011","journal-title":"Fertil. Steril."},{"issue":"4","key":"2025102819290906600_R35","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1093\/HUMUPD\/8.4.333","article-title":"Conception to ongoing pregnancy: the \u2018black box\u2019 of early pregnancy loss.","volume":"8","author":"Macklon","year":"2002","journal-title":"Hum. Reprod. Update"},{"issue":"9","key":"2025102819290906600_R36","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1093\/MOLEHR\/GAT032","article-title":"Critical role of hyaluronidase-2 during preimplantation embryo development.","volume":"19","author":"Marei","year":"2013","journal-title":"Mol. Hum. Reprod."},{"issue":"4","key":"2025102819290906600_R37","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1016\/J.THERIOGENOLOGY.2016.03.017","article-title":"Hyaluronan and hyaluronidase, which is better for embryo development?","volume":"86","author":"Marei","year":"2016","journal-title":"Theriogenology"},{"issue":"Suppl 2","key":"2025102819290906600_R38","doi-asserted-by":"publisher","first-page":"S26","DOI":"10.1016\/J.FERTNSTERT.2004.07.073","article-title":"Comparison of embryo transfers performed with G2.3 and embryo glue.","volume":"82","author":"Marek","year":"2004","journal-title":"Fertil. Steril."},{"issue":"12","key":"2025102819290906600_R39","doi-asserted-by":"publisher","first-page":"5320","DOI":"10.1210\/JC.2010-0603","article-title":"MUC1 as a discriminator between endometrium from fertile and infertile patients with PCOS and endometriosis.","volume":"95","author":"Margarit","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"7","key":"2025102819290906600_R40","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/S1471-4922(03)00122-3","article-title":"Mucin and Toll-like receptors in host defense against intestinal parasites.","volume":"19","author":"Moncada","year":"2003","journal-title":"Trends Parasitol."},{"issue":"7","key":"2025102819290906600_R41","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1007\/S10815-012-9758-2","article-title":"Hyaluronan-enriched transfer medium improves outcome in patients with multiple embryo transfer failures.","volume":"29","author":"Nakagawa","year":"2012","journal-title":"J. Assist. Reprod. Genet."},{"key":"2025102819290906600_R42","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1186\/1471-2407-10-512","article-title":"Hyaluronan synthases (HAS1\u20133) and hyaluronidases (HYAL1\u20132) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.","volume":"10","author":"Nykopp","year":"2010","journal-title":"BMC Cancer"},{"issue":"10","key":"2025102819290906600_R43","doi-asserted-by":"crossref","first-page":"4308","DOI":"10.1210\/endo.138.10.5431","article-title":"Progesterone regulates osteopontin expression in human trophoblasts: a model of paracrine control in the placenta?","volume":"138","author":"Omigbodun","year":"1997","journal-title":"Endocrinology"},{"key":"2025102819290906600_R44","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/J.DOMANIEND.2007.09.005","article-title":"Differences in the expression of luteinizing hormone and follicle-stimulating hormone receptors in the lower urinary tract between intact and gonadectomised male and female dogs.","volume":"34","author":"Ponglowhapan","year":"2008","journal-title":"Domest. Anim. Endocrinol."},{"issue":"5","key":"2025102819290906600_R45","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1530\/REP-13-0001","article-title":"Regulation of the hyaluronan system in ovine endometrium by ovarian steroids.","volume":"145","author":"Raheem","year":"2013","journal-title":"Reproduction"},{"issue":"9","key":"2025102819290906600_R46","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1093\/GLYCOB\/CWQ076","article-title":"Hyperglycemic conditions modulate connective tissue reorganization by human vascular smooth muscle cells through stimulation of hyaluronan synthesis.","volume":"20","author":"Sainio","year":"2010","journal-title":"Glycobiology"},{"issue":"2","key":"2025102819290906600_R47","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/S004410100452","article-title":"Distribution of hyaluronan in human endometrium across the menstrual cycle. Implications for implantation and menstruation.","volume":"306","author":"Salamonsen","year":"2001","journal-title":"Cell Tissue Res."},{"issue":"8","key":"2025102819290906600_R48","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1590\/S0100-879X2003000800013","article-title":"Distribution of versican and hyaluronan in the mouse uterus during decidualization.","volume":"36","author":"San Martin","year":"2003","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"2","key":"2025102819290906600_R49","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S1521-6934(02)00130-X","article-title":"The endometrium as a cause of implantation failure.","volume":"17","author":"Sharkey","year":"2003","journal-title":"Best Prac. Res. Clin. Obstet. Gynaecol."},{"issue":"6","key":"2025102819290906600_R50","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1016\/S0015-0282(03)00349-2","article-title":"Hyaluronic acid can successfully replace albumin as the sole macromolecule in a human embryo transfer medium.","volume":"79","author":"Simon","year":"2003","journal-title":"Fertil. Steril."},{"issue":"5","key":"2025102819290906600_R51","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/S0015-0282(98)00275-1","article-title":"Interleukin-1 receptor antagonist prevents embryonic implantation by a direct effect on the endometrial epithelium.","volume":"70","author":"Sim\u00f3n","year":"1998","journal-title":"Fertil. Steril."},{"issue":"1","key":"2025102819290906600_R52","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/J.1469-7580.2008.01034.X","article-title":"Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation.","volume":"215","author":"Singh","year":"2009","journal-title":"J. Anat."},{"key":"2025102819290906600_R53","doi-asserted-by":"publisher","first-page":"d1879","DOI":"10.2741\/SPENCER","article-title":"Biology of progesterone action during pregnancy recognition and maintenance of pregnancy.","volume":"7","author":"Spencer","year":"2002","journal-title":"Front. Biosci."},{"issue":"6","key":"2025102819290906600_R54","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1530\/REP.1.00398","article-title":"Implantation mechanisms: insights from the sheep.","volume":"128","author":"Spencer","year":"2004","journal-title":"Reproduction"},{"key":"2025102819290906600_R55","first-page":"379","article-title":"Fetal\u2013maternal interactions during the establishment of pregnancy in ruminants.","volume":"64","author":"Spencer","year":"2007","journal-title":"Soc. Reprod. Fertil. Suppl."},{"issue":"8","key":"2025102819290906600_R56","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1210\/endo.136.8.7628404","article-title":"Expression and steroid hormonal control of Muc-1 in the mouse uterus.","volume":"136","author":"Surveyor","year":"1995","journal-title":"Endocrinology"},{"issue":"1","key":"2025102819290906600_R57","first-page":"15","article-title":"EmbryoGlue the transfer medium with hyaluronan in the IVF+ET program.","volume":"72","author":"Svobodov\u00e1","year":"2007","journal-title":"Ceska Gynekol."},{"issue":"2","key":"2025102819290906600_R58","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/J.FERTNSTERT.2008.07.005","article-title":"Concentration and distribution of hyaluronic acid in mouse uterus throughout the estrous cycle.","volume":"92","author":"Teixeira Gomes","year":"2009","journal-title":"Fertil. Steril."},{"issue":"3","key":"2025102819290906600_R59","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1016\/J.FERTNSTERT.2007.07.1294","article-title":"Effect of hyaluronan-enriched transfer medium on implantation and pregnancy rates after Day 3 and Day 5 embryo transfers: a prospective randomized study.","volume":"90","author":"Urman","year":"2008","journal-title":"Fertil. Steril."},{"issue":"5","key":"2025102819290906600_R60","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1111\/J.1439-0531.2011.01752.X","article-title":"av\u00df3 Integrin may participate in conceptus attachment by regulating morphologic changes in the endometrium during peri-implantation in ovine.","volume":"46","author":"Wan","year":"2011","journal-title":"Reprod. Domest. Anim."},{"issue":"51","key":"2025102819290906600_R61","doi-asserted-by":"publisher","first-page":"43094","DOI":"10.1074\/JBC.M112.349209","article-title":"The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering.","volume":"287","author":"Yang","year":"2012","journal-title":"J. Biol. Chem."}],"container-title":["Reproduction, Fertility and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/29\/9\/1763\/308199\/rd16232.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/29\/9\/1763\/308199\/rd16232.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T23:29:12Z","timestamp":1761694152000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/rd\/article\/29\/9\/1763\/49725\/Influence-of-hyaluronan-on-endometrial-receptivity"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,11]]},"references-count":61,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,8,14]]}},"URL":"https:\/\/doi.org\/10.1071\/rd16232","relation":{},"ISSN":["1031-3613","1448-5990"],"issn-type":[{"value":"1031-3613","type":"print"},{"value":"1448-5990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,11]]}}}