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It is known that fluoxetine crosses the placental\u2013blood barrier and is excreted in breast milk. Consequently, indirect exposure of the infant occurs. Knowing that fluoxetine alters the balance of neurotransmitters in the central nervous system, several studies have shown that maternal exposure to this drug leads to various adverse effects on the nervous, reproductive and cardiovascular systems of the offspring. The aim of the present study was to evaluate the effects of exposure to fluoxetine during gestation and lactation on parameters related to steroid hormones in prepubertal and pubertal male and female rats. The endpoints evaluated were date of puberty onset, plasma testosterone and oestrogen concentrations before and after puberty onset and corticosterone concentration before and after adrenocorticotrophin stimulus. None of the parameters was affected by fluoxetine exposure.<\/jats:p>","DOI":"10.1071\/rd18279","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T22:07:55Z","timestamp":1550700475000},"page":"1002-1008","source":"Crossref","is-referenced-by-count":2,"title":["Maternal exposure to fluoxetine during gestation and lactation does not alter plasma concentrations of testosterone, oestrogen or corticosterone in peripubertal offspring"],"prefix":"10.1071","volume":"31","author":[{"given":"Matheus A.","family":"Barbosa","sequence":"first","affiliation":[{"name":"ADepartment of Physiological Sciences, Biological Sciences Center, State University of Londrina, PR-445, Km 380, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz F.","family":"Ver\u00edssimo","sequence":"additional","affiliation":[{"name":"ADepartment of Physiological Sciences, Biological Sciences Center, State University of Londrina, PR-445, Km 380, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela C. 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