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No studies have yet analysed whether Cd alters the presence and distribution of these carbohydrates. We aimed to evaluate the changes induced by Cd in the distribution pattern of N-acetylglucosamine, sialic acid, mannose and fucose on the sperm membrane in the epididymis (e.g. caput, corpus, cauda) and if it alters the epididymal epithelium. Male Wistar pups were treated with Cd doses (0.125, 0.25 and 0.5\u00a0mg\/kg) on postnatal days 1\u201349. At postnatal day 90, they were humanely killed, sperm samples were obtained from the epididymis and tissue samples were taken for histological analysis. Cd concentrations in the blood and epididymis increased in proportion to the dose administered and decreased the serum testosterone levels and sperm quality. Histological analysis revealed alterations in the epithelium in all Cd-treated groups. Cd altered the distribution patterns of carbohydrates and fluorescence indices. All these alterations affected the structure and functioning of sperm.<\/jats:p>","DOI":"10.1071\/rd20167","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T21:30:22Z","timestamp":1613683822000},"page":"349-362","source":"Crossref","is-referenced-by-count":7,"title":["Postnatal cadmium administration affects the presence and distribution of carbohydrates in the sperm membrane during maturation in the epididymis in adult Wistar rats"],"prefix":"10.1071","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1194-7633","authenticated-orcid":true,"given":"Joel","family":"Hern\u00e1ndez-Rodr\u00edguez","sequence":"first","affiliation":[{"name":"ADoctorado en Ciencias Biol\u00f3gicas y de la Salud, Universidad Aut\u00f3noma Metropolitana, Av. 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