{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:40:44Z","timestamp":1790019644643,"version":"4.0.1"},"reference-count":156,"publisher":"CSIRO Publishing","issue":"6","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":176,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1198172"],"award-info":[{"award-number":["APP1198172"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,31]]},"abstract":"<jats:title\/>\n                  <jats:p>Embryo implantation requires both a developmentally competent embryo and a receptive uterus. Impaired uterine receptivity is a common constraint on implantation success and reproductive outcome. Ovarian steroid hormones oestrogen and progesterone play a central role in establishing uterine receptivity, but other factors also contribute. One additional regulating factor is male partner seminal fluid. However, the full physiological impacts of seminal fluid on uterine receptivity and the specific molecular pathways involved are not yet completely defined. New advances in RNA-sequencing technologies provide a powerful means to examine how uterine tissues and cells respond to seminal fluid contact. Findings utilising sequencing technology provide strong cellular and molecular evidence in humans and mice that seminal fluid contact around the time of ovulation drives immune and vascular changes with potential to affect endometrial receptivity in the peri-implantation phase. This approach has led to the discovery of novel mediators and regulatory factors subsequently shown to facilitate embryo implantation in genetic mouse models, enabling functional validation. Here, we summarise the evidence from recent microarray and RNA-sequencing findings that seminal fluid contact can directly and indirectly impact the transcriptional state of endometrial tissue during the implantation window in mice and also in humans. Progress in elucidating the female reproductive tract response to seminal fluid will improve understanding of male partner effects on endometrial receptivity, and the knowledge gained will have practical applications for achieving healthy pregnancy and offspring outcomes.<\/jats:p>","DOI":"10.1071\/rd24162","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T18:37:26Z","timestamp":1742236646000},"source":"Crossref","is-referenced-by-count":11,"title":["Seminal fluid effects on uterine receptivity to embryo implantation: transcriptomic strategies to define molecular mechanisms"],"prefix":"10.1071","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9841-2094","authenticated-orcid":true,"given":"Hon Y.","family":"Chan","sequence":"first","affiliation":[{"name":"AThe Robinson Research Institute and School of Biomedicine, University of Adelaide, Adelaide, SA 5005, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9967-0084","authenticated-orcid":true,"given":"Sarah A.","family":"Robertson","sequence":"additional","affiliation":[{"name":"AThe Robinson Research Institute and School of Biomedicine, University of Adelaide, Adelaide, SA 5005, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[2025,3,18]]},"reference":[{"issue":"1","key":"2025111811530628600_R1","doi-asserted-by":"publisher","first-page":"R1","DOI":"10.1530\/REP-13-0358","article-title":"Prostasomes: extracellular vesicles from the prostate.","volume":"147","author":"Aalberts","year":"2014","journal-title":"Reproduction"},{"key":"2025111811530628600_R2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02387","article-title":"Uterine immunity and microbiota: a shifting paradigm.","volume":"10","author":"Agostinis","year":"2019","journal-title":"Frontiers in Immunology"},{"issue":"7","key":"2025111811530628600_R3","doi-asserted-by":"publisher","DOI":"10.1111\/and.14077","article-title":"The role of sperm in inducing genomic changes in the implantation: an experimental study.","volume":"53","author":"Ajdary","year":"2021","journal-title":"Andrologia"},{"issue":"3","key":"2025111811530628600_R4","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1038\/ni1037","article-title":"Regulatory T cells mediate maternal tolerance to the fetus.","volume":"5","author":"Aluvihare","year":"2004","journal-title":"Nature Immunology"},{"issue":"6","key":"2025111811530628600_R5","doi-asserted-by":"publisher","first-page":"3070","DOI":"10.4049\/jimmunol.1303117","article-title":"Identification of a novel neutrophil population: proangiogenic granulocytes in second-trimester human decidua.","volume":"193","author":"Amsalem","year":"2014","journal-title":"The Journal of Immunology"},{"issue":"5","key":"2025111811530628600_R6","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1053\/beog.2000.0116","article-title":"The cell biological basis of human implantation.","volume":"14","author":"Aplin","year":"2000","journal-title":"Best Practice & Research Clinical Obstetrics & Gynaecology"},{"issue":"1","key":"2025111811530628600_R7","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1242\/jcs.175943","article-title":"Embryo-epithelium interactions during implantation at a glance.","volume":"130","author":"Aplin","year":"2017","journal-title":"Journal of Cell Science"},{"issue":"4","key":"2025111811530628600_R8","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1093\/humrep\/deac022","article-title":"Use of \u2018omics for endometrial timing: the cycle moves on.","volume":"37","author":"Aplin","year":"2022","journal-title":"Human Reproduction"},{"issue":"1","key":"2025111811530628600_R9","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.114.120642","article-title":"Seminal vesicle secretion 2 acts as a protectant of sperm sterols and prevents ectopic sperm capacitation in mice.","volume":"92","author":"Araki","year":"2015","journal-title":"Biology of Reproduction"},{"issue":"6","key":"2025111811530628600_R10","doi-asserted-by":"publisher","first-page":"2937","DOI":"10.4049\/jimmunol.171.6.2937","article-title":"Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy.","volume":"171","author":"Ashkar","year":"2003","journal-title":"The Journal of Immunology"},{"issue":"2","key":"2025111811530628600_R11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.cd011809.pub2","article-title":"Application of seminal plasma to female genital tract prior to embryo transfer in assisted reproductive technology cycles (IVF, ICSI and frozen embryo transfer).","volume":"2","author":"Ata","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"2025111811530628600_R12","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/j.1439-0272.1992.tb02636.x","article-title":"Morphology and functions of the human seminal vesicle.","volume":"24","author":"Aum\u00fcller","year":"1992","journal-title":"Andrologia"},{"issue":"1","key":"2025111811530628600_R13","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1016\/j.bbrc.2017.11.100","article-title":"Induction of immune-related gene expression by seminal exosomes in the porcine endometrium.","volume":"495","author":"Bai","year":"2018","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"2","key":"2025111811530628600_R14","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.113.110486","article-title":"Epididymosomes convey different repertoires of micrornas throughout the bovine epididymis.","volume":"89","author":"Belleann\u00e9e","year":"2013","journal-title":"Biology of Reproduction"},{"issue":"2","key":"2025111811530628600_R15","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/S0015-0282(16)49521-X","article-title":"The influence of patient insemination on the implantation rate in an in vitro fertilization and embryo transfer program.","volume":"46","author":"Bellinge","year":"1986","journal-title":"Fertility and Sterility"},{"issue":"4","key":"2025111811530628600_R16","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1095\/biolreprod.107.060632","article-title":"Dendritic cells: key to fetal tolerance?","volume":"77","author":"Blois","year":"2007","journal-title":"Biology of Reproduction"},{"issue":"3","key":"2025111811530628600_R17","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/0165-0378(95)00941-D","article-title":"Reduction of ovulation rate in the rat by administration of a neutrophil-depleting monoclonal antibody.","volume":"29","author":"Br\u00e4nnstr\u00f6m","year":"1995","journal-title":"Journal of Reproductive Immunology"},{"issue":"3","key":"2025111811530628600_R18","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/BF02820507","article-title":"Progesterone-dependent decidualization of the human endometrium is mediated by cAMP.","volume":"6","author":"Brar","year":"1997","journal-title":"Endocrine"},{"issue":"6","key":"2025111811530628600_R19","doi-asserted-by":"publisher","first-page":"2200","DOI":"10.1073\/pnas.1305609111","article-title":"Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring.","volume":"111","author":"Bromfield","year":"2014","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"8","key":"2025111811530628600_R20","doi-asserted-by":"publisher","first-page":"3472","DOI":"10.1172\/JCI60561","article-title":"Macrophages regulate corpus luteum development during embryo implantation in mice.","volume":"123","author":"Care","year":"2013","journal-title":"The Journal of Clinical Investigation"},{"issue":"1","key":"2025111811530628600_R21","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1161\/HYPERTENSIONAHA.118.10858","article-title":"Reduction in regulatory T cells in early pregnancy causes uterine artery dysfunction in mice.","volume":"72","author":"Care","year":"2018","journal-title":"Hypertension"},{"issue":"8","key":"2025111811530628600_R22","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.7754\/Clin.Lab.2016.151229","article-title":"High concentrations of the angiogenic peptide VEGF-A in seminal fluid and its association to prostasomes.","volume":"62","author":"Carlsson","year":"2016","journal-title":"Clinical Laboratory"},{"issue":"5","key":"2025111811530628600_R23","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaae017","article-title":"In vivo effect of vaginal seminal plasma application on the human endometrial transcriptome: a randomized controlled trial.","volume":"30","author":"Catalini","year":"2024","journal-title":"Molecular Human Reproduction"},{"issue":"12","key":"2025111811530628600_R24","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy.","volume":"18","author":"Cha","year":"2012","journal-title":"Nature Medicine"},{"issue":"1","key":"2025111811530628600_R25","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-95213-1","article-title":"Toll-like receptor-4 null mutation causes fetal loss and fetal growth restriction associated with impaired maternal immune tolerance in mice.","volume":"11","author":"Chan","year":"2021","journal-title":"Scientific Reports"},{"issue":"1","key":"2025111811530628600_R26","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-023-09698-3","article-title":"The endometrial transcriptome transition preceding receptivity to embryo implantation in mice.","volume":"24","author":"Chan","year":"2023","journal-title":"BMC Genomics"},{"issue":"1","key":"2025111811530628600_R27","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S0950-3552(05)80077-X","article-title":"Frequency of implantation and early pregnancy loss in natural cycles.","volume":"5","author":"Chard","year":"1991","journal-title":"Bailli\u00e8re\u2019s Clinical Obstetrics and Gynaecology"},{"issue":"12","key":"2025111811530628600_R28","doi-asserted-by":"publisher","first-page":"4365","DOI":"10.1210\/endo.141.12.7855","article-title":"Leukemia inhibitory factor can substitute for nidatory estrogen and is essential to inducing a receptive uterus for implantation but is not essential for subsequent embryogenesis.","volume":"141","author":"Chen","year":"2000","journal-title":"Endocrinology"},{"issue":"6","key":"2025111811530628600_R29","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1093\/humrep\/deu047","article-title":"Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.","volume":"29","author":"Chen","year":"2014","journal-title":"Human Reproduction"},{"issue":"3","key":"2025111811530628600_R30","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s00429-002-0290-5","article-title":"Embryos sired by males without accessory sex glands induce failure of uterine support: a study of VEGF, MMP and TGF expression in the golden hamster.","volume":"206","author":"Chow","year":"2003","journal-title":"Anatomy and Embryology"},{"issue":"2","key":"2025111811530628600_R31","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1093\/humupd\/dmu052","article-title":"The role of seminal plasma for improved outcomes during in vitro fertilization treatment: review of the literature and meta-analysis.","volume":"21","author":"Crawford","year":"2015","journal-title":"Human Reproduction Update"},{"issue":"6","key":"2025111811530628600_R32","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1016\/j.devcel.2011.09.010","article-title":"Conditional deletion of MSX homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity.","volume":"21","author":"Daikoku","year":"2011","journal-title":"Developmental Cell"},{"issue":"10","key":"2025111811530628600_R33","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1093\/molehr\/6.10.907","article-title":"Expression of interleukin-11 during the human menstrual cycle: coincidence with stromal cell decidualization and relationship to leukaemia inhibitory factor and prolactin.","volume":"6","author":"Dimitriadis","year":"2000","journal-title":"Molecular Human Reproduction"},{"issue":"6","key":"2025111811530628600_R34","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1093\/humupd\/dmi023","article-title":"Cytokines, chemokines and growth factors in endometrium related to implantation.","volume":"11","author":"Dimitriadis","year":"2005","journal-title":"Human Reproduction Update"},{"key":"2025111811530628600_R35","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1146\/annurev-immunol-032712-100003","article-title":"Immunology of the maternal-fetal interface.","volume":"31","author":"Erlebacher","year":"2013","journal-title":"Annual Review of Immunology"},{"issue":"11","key":"2025111811530628600_R36","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1038\/nrendo.2016.116","article-title":"Fertile ground: human endometrial programming and lessons in health and disease.","volume":"12","author":"Evans","year":"2016","journal-title":"Nature Reviews Endrocrinology"},{"key":"2025111811530628600_R37","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00298","article-title":"Monocytes and macrophages in pregnancy and pre-eclampsia.","volume":"5","author":"Faas","year":"2014","journal-title":"Frontiers in Immunology"},{"issue":"3","key":"2025111811530628600_R38","doi-asserted-by":"publisher","first-page":"E231","DOI":"10.1073\/pnas.1206322110","article-title":"Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal\u2013fetal interface.","volume":"110","author":"Fu","year":"2013","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"5","key":"2025111811530628600_R39","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1093\/humrep\/17.5.1199","article-title":"Angiogenesis occurs by vessel elongation in proliferative phase human endometrium.","volume":"17","author":"Gambino","year":"2002","journal-title":"Human Reproduction"},{"issue":"4","key":"2025111811530628600_R40","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1095\/biolreprod.104.027425","article-title":"Seminal plasma regulates corpora lutea macrophage populations during early pregnancy in mice.","volume":"71","author":"Gangnuss","year":"2004","journal-title":"Biology of Reproduction"},{"issue":"1","key":"2025111811530628600_R41","first-page":"59","article-title":"Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility.","volume":"6","author":"Garrido","year":"2004","journal-title":"Asian Journal of Andrology"},{"issue":"3","key":"2025111811530628600_R42","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1093\/humrep\/deaa015","article-title":"Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.","volume":"35","author":"George","year":"2020","journal-title":"Human Reproduction"},{"issue":"7","key":"2025111811530628600_R43","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1084\/jem.20050463","article-title":"Tumor cells convert immature myeloid dendritic cells into TGF-\u03b2\u2013secreting cells inducing CD4+CD25+ regulatory T cell proliferation.","volume":"202","author":"Ghiringhelli","year":"2005","journal-title":"The Journal of Experimental Medicine"},{"issue":"2","key":"2025111811530628600_R44","doi-asserted-by":"publisher","first-page":"294","DOI":"10.61186\/rbmb.12.2.294","article-title":"Investigation of the effect of seminal plasma exosomes from the normal and oligoasthenoteratospermic males in the implantation process.","volume":"12","author":"Gholipour","year":"2023","journal-title":"Reports of Biochemistry and Molecular Biology"},{"key":"2025111811530628600_R45","doi-asserted-by":"publisher","DOI":"10.1038\/srep19970","article-title":"Intracrine androgens enhance decidualization and modulate expression of human endometrial receptivity genes.","volume":"6","author":"Gibson","year":"2016","journal-title":"Scientific Reports"},{"issue":"2","key":"2025111811530628600_R46","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1095\/biolreprod.110.088591","article-title":"Seminal fluid regulates accumulation of FOXP3+ regulatory T cells in the preimplantation mouse uterus through expanding the FOXP3+ cell pool and CCL19-mediated recruitment.","volume":"85","author":"Guerin","year":"2011","journal-title":"Biology of Reproduction"},{"issue":"12","key":"2025111811530628600_R47","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1093\/molehr\/gag095","article-title":"Seminal plasma induces mRNA expression of IL-1\u03b2, IL-6 and LIF in endometrial epithelial cells in vitro.","volume":"9","author":"Gutsche","year":"2003","journal-title":"Molecular Human Reproduction"},{"issue":"9","key":"2025111811530628600_R48","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1038\/nm1452","article-title":"Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.","volume":"12","author":"Hanna","year":"2006","journal-title":"Nature Medicine"},{"issue":"2","key":"2025111811530628600_R49","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/S0950-3552(05)80092-6","article-title":"The implantation window.","volume":"6","author":"Harper","year":"1992","journal-title":"Bailli\u00e8re\u2019s Clinical Obstetrics and Gynaecology"},{"key":"2025111811530628600_R50","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.969336","article-title":"Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development.","volume":"13","author":"Hebeda","year":"2022","journal-title":"Frontiers in Immunology"},{"key":"2025111811530628600_R51","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.169836","article-title":"Regulatory T cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice.","volume":"10","author":"Hosking","year":"2025","journal-title":"JCI Insight"},{"issue":"1","key":"2025111811530628600_R52","doi-asserted-by":"publisher","DOI":"10.1186\/s40834-023-00218-y","article-title":"Impact of sexual intercourse on frozen-thawed embryo transfer outcomes: a randomized controlled trial.","volume":"8","author":"Hou","year":"2023","journal-title":"Contraception and Reproductive Medicine"},{"issue":"6","key":"2025111811530628600_R53","doi-asserted-by":"publisher","first-page":"1562","DOI":"10.1095\/biolreprod.103.024794","article-title":"Diversity in phenotype and steroid hormone dependence in dendritic cells and macrophages in the mouse uterus.","volume":"70","author":"Hudson Keenihan","year":"2004","journal-title":"Biology of Reproduction"},{"issue":"1","key":"2025111811530628600_R54","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1095\/biolreprod.110.085399","article-title":"Macrophage-derived LIF and IL1B regulate alpha(1,2)fucosyltransferase 2 (Fut2) expression in mouse uterine epithelial cells during early pregnancy.","volume":"84","author":"Jasper","year":"2011","journal-title":"Biology of Reproduction"},{"issue":"2","key":"2025111811530628600_R55","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1189\/jlb.0806517","article-title":"Mechanisms underlying TGF-\u03b21-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis.","volume":"81","author":"Jeon","year":"2007","journal-title":"Journal of Leukocyte Biology"},{"issue":"12","key":"2025111811530628600_R56","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1038\/s41423-018-0008-0","article-title":"Three macrophage subsets are identified in the uterus during early human pregnancy.","volume":"15","author":"Jiang","year":"2018","journal-title":"Cellular & Molecular Immunology"},{"key":"2025111811530628600_R57","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1067661","article-title":"Insights into the immunomodulatory regulation of matrix metalloproteinase at the maternal-fetal interface during early pregnancy and pregnancy-related diseases.","volume":"13","author":"Jing","year":"2023","journal-title":"Frontiers in Immunology"},{"issue":"3","key":"2025111811530628600_R58","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.112.103564","article-title":"Seminal plasma affects prostaglandin synthesis and angiogenesis in the porcine uterus.","volume":"88","author":"Kaczmarek","year":"2013","journal-title":"Biology of Reproduction"},{"key":"2025111811530628600_R59"},{"issue":"11","key":"2025111811530628600_R60","doi-asserted-by":"publisher","first-page":"4145","DOI":"10.1073\/pnas.1320715111","article-title":"Seminal vesicle protein SVS2 is required for sperm survival in the uterus.","volume":"111","author":"Kawano","year":"2014","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"3","key":"2025111811530628600_R61","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1111\/j.1365-2249.1991.tb02968.x","article-title":"Extracellular organelles (prostasomes) are immunosuppressive components of human semen.","volume":"86","author":"Kelly","year":"1991","journal-title":"Clinical and Experimental Immunology"},{"issue":"1","key":"2025111811530628600_R62","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/0165-0378(93)00862-N","article-title":"The immunosuppressive contribution of prostaglandin components of human semen and their ability to elevate cyclic adenosine monophosphate levels in peripheral blood mononuclear cells.","volume":"26","author":"Kelly","year":"1994","journal-title":"Journal of Reproductive Immunology"},{"issue":"4","key":"2025111811530628600_R63","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1093\/humrep\/12.4.677","article-title":"A cytokine switch induced by human seminal plasma: an immune modulation with implications for sexually transmitted disease.","volume":"12","author":"Kelly","year":"1997","journal-title":"Human Reproduction"},{"key":"2025111811530628600_R64","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4359","article-title":"MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling.","volume":"5","author":"Kieckbusch","year":"2014","journal-title":"Nature Communications"},{"issue":"9","key":"2025111811530628600_R65","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1002\/emmm.201302618","article-title":"VEGF \u2013 a regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.","volume":"5","author":"Kim","year":"2013","journal-title":"EMBO Molecular Medicine"},{"issue":"5","key":"2025111811530628600_R66","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1073\/pnas.1413493112","article-title":"Seminal CD38 is a pivotal regulator for fetomaternal tolerance.","volume":"112","author":"Kim","year":"2015","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"2","key":"2025111811530628600_R67","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1111\/j.1600-0897.2009.00720.x","article-title":"Timed sexual intercourse facilitates the recruitment of uterine CD56bright natural killer cells in women with infertility.","volume":"62","author":"Kimura","year":"2009","journal-title":"American Journal of Reproductive Immunology"},{"issue":"4","key":"2025111811530628600_R68","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202002217R","article-title":"Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation.","volume":"35","author":"Kong","year":"2021","journal-title":"The FASEB Journal"},{"issue":"26","key":"2025111811530628600_R69","doi-asserted-by":"publisher","first-page":"15677","DOI":"10.1073\/pnas.95.26.15677","article-title":"Generation and reproductive phenotypes of mice lacking estrogen receptor \u03b2.","volume":"95","author":"Krege","year":"1998","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"2","key":"2025111811530628600_R71","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1111\/jcmm.14027","article-title":"Autocrine VEGF signalling on M2 macrophages regulates PD-L1 expression for immunomodulation of T cells.","volume":"23","author":"Lai","year":"2019","journal-title":"Journal of Cellular and Molecular Medicine"},{"issue":"3-4","key":"2025111811530628600_R72","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/0165-2427(94)05320-R","article-title":"Immunomodulatory effects of extracellular secretory vesicles isolated from bovine semen.","volume":"44","author":"Lazarevic","year":"1995","journal-title":"Veterinary Immunology and Immunopathology"},{"issue":"3","key":"2025111811530628600_R73","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1530\/REP-07-0167","article-title":"Immunoendocrine aspects of endometrial function and implantation.","volume":"134","author":"Lea","year":"2007","journal-title":"Reproduction"},{"issue":"6","key":"2025111811530628600_R74","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1530\/rep.1.00340","article-title":"Animal models of implantation.","volume":"128","author":"Lee","year":"2004","journal-title":"Reproduction"},{"issue":"6","key":"2025111811530628600_R75","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.tem.2007.06.002","article-title":"Mouse models of implantation.","volume":"18","author":"Lee","year":"2007","journal-title":"Trends in Endocrinology & Metabolism"},{"issue":"1","key":"2025111811530628600_R76","doi-asserted-by":"publisher","first-page":"16","DOI":"10.4110\/in.2015.15.1.16","article-title":"Immune cells in the female reproductive tract.","volume":"15","author":"Lee","year":"2015","journal-title":"Immune Network"},{"issue":"4","key":"2025111811530628600_R77","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.fertnstert.2019.02.009","article-title":"What exactly is endometrial receptivity?","volume":"111","author":"Lessey","year":"2019","journal-title":"Fertility and Sterility"},{"issue":"1","key":"2025111811530628600_R78","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.fertnstert.2024.02.002","article-title":"Intravaginal exposure to seminal plasma after ovum pick-up does not increase live birth rates after in vitro fertilization or intracytoplasmic sperm injection treatment: a double-blind, placebo-controlled randomized trial.","volume":"122","author":"Liffner","year":"2024","journal-title":"Fertility and Sterility"},{"issue":"2","key":"2025111811530628600_R79","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0092-8674(00)80402-X","article-title":"Multiple female reproductive failures in cyclooxygenase 2-deficient mice.","volume":"91","author":"Lim","year":"1997","journal-title":"Cell"},{"issue":"18","key":"2025111811530628600_R80","doi-asserted-by":"publisher","first-page":"2266","DOI":"10.1101\/gad.9.18.2266","article-title":"Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.","volume":"9","author":"Lydon","year":"1995","journal-title":"Genes & Development"},{"issue":"7","key":"2025111811530628600_R81","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1111\/andr.13424","article-title":"Immune regulatory cytokines in seminal plasma of healthy men: a scoping review and analysis of variance.","volume":"11","author":"Lyons","year":"2023","journal-title":"Andrology"},{"issue":"1-2","key":"2025111811530628600_R82","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0165-0378(01)00063-8","article-title":"A repertoire of cytokines in human seminal plasma.","volume":"54","author":"Maegawa","year":"2002","journal-title":"Journal of Reproductive Immunology"},{"issue":"12","key":"2025111811530628600_R83","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.it.2004.09.015","article-title":"The chemokine system in diverse forms of macrophage activation and polarization.","volume":"25","author":"Mantovani","year":"2004","journal-title":"Trends in Immunology"},{"key":"2025111811530628600_R84","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.640907","article-title":"Illuminating the \u201cblack box\u201d of progesterone-dependent embryo implantation using engineered mice.","volume":"9","author":"Maurya","year":"2021","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"2-3-4","key":"2025111811530628600_R85","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1387\/ijdb.140020dw","article-title":"The evolution of embryo implantation.","volume":"58","author":"McGowen","year":"2014","journal-title":"The International Journal of Developmental Biology"},{"issue":"52","key":"2025111811530628600_R86","doi-asserted-by":"publisher","first-page":"E8415","DOI":"10.1073\/pnas.1611944114","article-title":"Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy.","volume":"113","author":"Nadkarni","year":"2016","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"2","key":"2025111811530628600_R87","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002500","article-title":"MSX homeobox genes critically regulate embryo implantation by controlling paracrine signaling between uterine stroma and epithelium.","volume":"8","author":"Nallasamy","year":"2012","journal-title":"PLoS Genetics"},{"issue":"6","key":"2025111811530628600_R88","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1071\/RD13153","article-title":"A novel subclass of bovine \u03b2-defensins links reproduction and immunology.","volume":"26","author":"Narciandi","year":"2014","journal-title":"Reproduction, Fertility and Development"},{"issue":"11","key":"2025111811530628600_R89","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1113\/EP085567","article-title":"Metalloproteinase production from macrophages \u2013 a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction.","volume":"101","author":"Newby","year":"2016","journal-title":"Experimental Physiology"},{"issue":"1","key":"2025111811530628600_R90","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1600-0897.1993.tb00594.x","article-title":"Transforming growth factor \u03b2 as an immunosuppressive protein in human seminal plasma.","volume":"30","author":"Nocera","year":"1993","journal-title":"American Journal of Reproductive Immunology"},{"issue":"4","key":"2025111811530628600_R91","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/S1472-6483(10)60649-9","article-title":"Defective implantation and placentation: laying the blueprint for pregnancy complications.","volume":"13","author":"Norwitz","year":"2006","journal-title":"Reproductive BioMedicine Online"},{"issue":"1","key":"2025111811530628600_R92","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1530\/jrf.0.0840341","article-title":"Effects of male accessory sex gland secretions on early embryonic development in the golden hamster.","volume":"84","author":"O","year":"1988","journal-title":"Journal of Reproduction and Fertility"},{"issue":"2","key":"2025111811530628600_R93","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1530\/rep.1.00160","article-title":"Seminal plasma regulates endometrial cytokine expression, leukocyte recruitment and embryo development in the pig.","volume":"128","author":"O\u2019Leary","year":"2004","journal-title":"Reproduction"},{"issue":"11","key":"2025111811530628600_R94","doi-asserted-by":"publisher","DOI":"10.3390\/cells10113055","article-title":"Vascular dysfunction in preeclampsia.","volume":"10","author":"Opichka","year":"2021","journal-title":"Cells"},{"issue":"173","key":"2025111811530628600_R95","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2001595","article-title":"Ca2+ signaling tools acquired from prostasomes are required for progesterone-induced sperm motility.","volume":"4","author":"Park","year":"2011","journal-title":"Science Signaling"},{"issue":"5","key":"2025111811530628600_R96","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2006-7-5-r40","article-title":"Large-scale and high-confidence proteomic analysis of human seminal plasma.","volume":"7","author":"Pilch","year":"2006","journal-title":"Genome Biology"},{"issue":"1","key":"2025111811530628600_R97","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1093\/molehr\/gah257","article-title":"Membrane-type matrix metalloproteinases and vascularization in human endometrium during the menstrual cycle.","volume":"12","author":"Plaisier","year":"2006","journal-title":"Molecular Human Reproduction"},{"issue":"12","key":"2025111811530628600_R98","doi-asserted-by":"publisher","first-page":"3954","DOI":"10.1172\/JCI36682","article-title":"Uterine DCs are crucial for decidua formation during embryo implantation in mice.","volume":"118","author":"Plaks","year":"2008","journal-title":"The Journal of Clinical Investigation"},{"issue":"11","key":"2025111811530628600_R99","doi-asserted-by":"publisher","first-page":"11682","DOI":"10.1096\/fj.201900662R","article-title":"Evidence for shared molecular pathways of dysregulated decidualization in preeclampsia and endometrial disorders revealed by microarray data integration.","volume":"33","author":"Rabaglino","year":"2019","journal-title":"The FASEB Journal"},{"issue":"1","key":"2025111811530628600_R100","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/S0093-691X(01)00659-8","article-title":"High rates of embryonic loss, yet high incidence of multiple births in human art: is this paradoxical?","volume":"57","author":"Racowsky","year":"2002","journal-title":"Theriogenology"},{"issue":"1-2","key":"2025111811530628600_R101","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.anireprosci.2014.04.016","article-title":"Seminal plasma proteome of electroejaculated Bos indicus bulls.","volume":"148","author":"Rego","year":"2014","journal-title":"Animal Reproduction Science"},{"issue":"1","key":"2025111811530628600_R102","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1002\/(SICI)1520-6408(1997)21:1&lt;6::AID-DVG2&gt;3.0.CO;2-B","article-title":"Molecular genetics of implantation in the mouse.","volume":"21","author":"Rinkenberger","year":"1997","journal-title":"Developmental Genetics"},{"issue":"1-2","key":"2025111811530628600_R103","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/S0165-0378(02)00012-8","article-title":"Leukemia inhibitory factor and interleukin-11: cytokines with key roles in implantation.","volume":"57","author":"Robb","year":"2002","journal-title":"Journal of Reproductive Immunology"},{"key":"2025111811530628600_R104","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.placenta.2017.07.012","article-title":"Global pregnancy collaboration symposium: prepregnancy and very early pregnancy antecedents of adverse pregnancy outcomes: overview and recommendations.","volume":"60","author":"Roberts","year":"2017","journal-title":"Placenta"},{"issue":"1","key":"2025111811530628600_R105","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s00441-005-1127-3","article-title":"Seminal plasma and male factor signalling in the female reproductive tract.","volume":"322","author":"Robertson","year":"2005","journal-title":"Cell and Tissue Research"},{"issue":"4","key":"2025111811530628600_R106","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1071\/RD9900359","article-title":"Granulocyte macrophage colony stimulating factor (GM-CSF) in the murine reproductive tract: stimulation by seminal factors.","volume":"2","author":"Robertson","year":"1990","journal-title":"Reproduction, Fertility and Development"},{"issue":"3","key":"2025111811530628600_R107","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.fertnstert.2016.07.1101","article-title":"Seminal fluid and fertility in women.","volume":"106","author":"Robertson","year":"2016","journal-title":"Fertility and Sterility"},{"issue":"2","key":"2025111811530628600_R108","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1530\/jrf.0.1070265","article-title":"Role of high molecular weight seminal vesicle proteins in eliciting the uterine inflammatory response to semen in mice.","volume":"107","author":"Robertson","year":"1996","journal-title":"Journal of Reproduction and Fertility"},{"issue":"2","key":"2025111811530628600_R109","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0165-0378(99)00060-1","article-title":"Granulocyte-macrophage colony-stimulating factor (GM-CSF) targets myeloid leukocytes in the uterus during the post-mating inflammatory response in mice.","volume":"46","author":"Robertson","year":"2000","journal-title":"Journal of Reproductive Immunology"},{"issue":"5","key":"2025111811530628600_R110","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1095\/biolreprod.108.074658","article-title":"Seminal fluid drives expansion of the CD4+CD25+ T regulatory cell pool and induces tolerance to paternal alloantigens in mice.","volume":"80","author":"Robertson","year":"2009","journal-title":"Biology of Reproduction"},{"issue":"10","key":"2025111811530628600_R111","doi-asserted-by":"publisher","first-page":"4224","DOI":"10.1172\/JCI122182","article-title":"Regulatory T cells in embryo implantation and the immune response to pregnancy.","volume":"128","author":"Robertson","year":"2018","journal-title":"The Journal of Clinical Investigation"},{"issue":"6","key":"2025111811530628600_R112","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.fertnstert.2022.04.023","article-title":"Immune determinants of endometrial receptivity: a biological perspective.","volume":"117","author":"Robertson","year":"2022","journal-title":"Fertility and Sterility"},{"issue":"1","key":"2025111811530628600_R113","doi-asserted-by":"publisher","DOI":"10.1080\/20013078.2019.1565262","article-title":"In vitro decidualisation of human endometrial stromal cells is enhanced by seminal fluid extracellular vesicles.","volume":"8","author":"Rodriguez-Caro","year":"2019","journal-title":"Journal of Extracellular Vesicles"},{"issue":"2","key":"2025111811530628600_R114","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1111\/1471-0528.15004","article-title":"Effectiveness of seminal plasma in in vitro fertilisation treatment: a systematic review and meta-analysis.","volume":"126","author":"Saccone","year":"2019","journal-title":"BJOG: An International Journal of Obstetrics & Gynaecology"},{"issue":"2","key":"2025111811530628600_R115","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3109\/03009730903366067","article-title":"Secretions from seminal vesicles lack characteristic markers for prostasomes.","volume":"115","author":"Sahl\u00e9n","year":"2010","journal-title":"Upsala Journal of Medical Sciences"},{"issue":"1","key":"2025111811530628600_R116","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12600","article-title":"Role of immune cells in the establishment of implantation and maintenance of pregnancy and immunomodulatory therapies for patients with repeated implantation failure and recurrent pregnancy loss.","volume":"23","author":"Saito","year":"2024","journal-title":"Reproductive Medicine and Biology"},{"issue":"6","key":"2025111811530628600_R117","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1055\/s-2007-991041","article-title":"Cytokines and chemokines during human embryo implantation: roles in implantation and early placentation.","volume":"25","author":"Salamonsen","year":"2007","journal-title":"Seminars in Reproductive Medicine"},{"issue":"10","key":"2025111811530628600_R118","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1016\/j.bbamcr.2012.06.021","article-title":"Seminal plasma induces angiogenic chemokine expression in cervical cancer cells and regulates vascular function.","volume":"1823","author":"Sales","year":"2012","journal-title":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"},{"issue":"1","key":"2025111811530628600_R119","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.cell.2012.05.031","article-title":"Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict.","volume":"150","author":"Samstein","year":"2012","journal-title":"Cell"},{"issue":"1","key":"2025111811530628600_R120","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/j.1439-0531.2012.02019.x","article-title":"Vascular endothelial (VEGF) and epithelial growth factor (EGF) as well as platelet-activating factor (PAF) and receptors are expressed in the early pregnant canine uterus.","volume":"48","author":"Sch\u00e4fer-Somi","year":"2013","journal-title":"Reproduction in Domestic Animals"},{"issue":"s3","key":"2025111811530628600_R121","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/rda.12383","article-title":"Seminal fluid and immune adaptation for pregnancy \u2013 comparative biology in mammalian species.","volume":"49","author":"Schjenken","year":"2014","journal-title":"Reproduction in Domestic Animals"},{"key":"2025111811530628600_R122"},{"issue":"3","key":"2025111811530628600_R123","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1152\/physrev.00013.2018","article-title":"The female response to seminal fluid.","volume":"100","author":"Schjenken","year":"2020","journal-title":"Physiological Reviews"},{"issue":"3","key":"2025111811530628600_R124","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.114.125740","article-title":"TLR4 signaling is a major mediator of the female tract response to seminal fluid in mice.","volume":"93","author":"Schjenken","year":"2015","journal-title":"Biology of Reproduction"},{"issue":"1","key":"2025111811530628600_R125","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02038-9","article-title":"Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice.","volume":"4","author":"Schjenken","year":"2021","journal-title":"Communications Biology"},{"issue":"1","key":"2025111811530628600_R126","doi-asserted-by":"publisher","first-page":"15","DOI":"10.5935\/1518-0557.20180001","article-title":"Is the risk of preeclampsia higher in donor oocyte pregnancies? A systematic review and meta-analysis.","volume":"22","author":"Schwarze","year":"2018","journal-title":"JBRA Assisted Reproduction"},{"issue":"8561","key":"2025111811530628600_R127","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91104-4","article-title":"Immune basis for pre-eclampsia: evidence from oocyte recipients.","volume":"330","author":"Serhal","year":"1987","journal-title":"The Lancet"},{"issue":"7","key":"2025111811530628600_R128","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1093\/molehr\/gam028","article-title":"Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells.","volume":"13","author":"Sharkey","year":"2007","journal-title":"Molecular Human Reproduction"},{"issue":"2","key":"2025111811530628600_R129","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.4049\/jimmunol.1200005","article-title":"TGF-\u03b2 mediates proinflammatory seminal fluid signaling in human cervical epithelial cells.","volume":"189","author":"Sharkey","year":"2012","journal-title":"The Journal of Immunology"},{"issue":"5","key":"2025111811530628600_R130","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.4049\/jimmunol.1102736","article-title":"Seminal fluid induces leukocyte recruitment and cytokine and chemokine mRNA expression in the human cervix after coitus.","volume":"188","author":"Sharkey","year":"2012","journal-title":"The Journal of Immunology"},{"issue":"10","key":"2025111811530628600_R131","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1093\/humrep\/dew185","article-title":"Seminal plasma transforming growth factor-\u03b2, activin A and follistatin fluctuate within men over time.","volume":"31","author":"Sharkey","year":"2016","journal-title":"Human Reproduction"},{"issue":"7","key":"2025111811530628600_R132","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1093\/humrep\/dex106","article-title":"Seminal plasma pro-inflammatory cytokines interferon-\u03b3 (IFNG) and C-X-C motif chemokine ligand 8 (CXCL8) fluctuate over time within men.","volume":"32","author":"Sharkey","year":"2017","journal-title":"Human Reproduction"},{"issue":"3","key":"2025111811530628600_R133","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1093\/biolre\/ioy071","article-title":"Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells.","volume":"99","author":"Sharkey","year":"2018","journal-title":"Biology of Reproduction"},{"issue":"2","key":"2025111811530628600_R134","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.jri.2010.02.006","article-title":"Regulatory T cells are necessary for implantation and maintenance of early pregnancy but not late pregnancy in allogeneic mice.","volume":"85","author":"Shima","year":"2010","journal-title":"Journal of Reproductive Immunology"},{"issue":"2","key":"2025111811530628600_R70","doi-asserted-by":"publisher","DOI":"10.3390\/proteomes7020017","article-title":"Isolation and characterization of small extracellular vesicles from porcine blood plasma, cerebrospinal fluid, and seminal plasma.","volume":"7","author":"Skalnikova","year":"2019","journal-title":"Proteomes"},{"issue":"1","key":"2025111811530628600_R135","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-021-07951-1","article-title":"Transcriptomic analysis of the seminal vesicle response to the reproductive toxicant acrylamide.","volume":"22","author":"Skerrett-Byrne","year":"2021","journal-title":"BMC Genomics"},{"issue":"2","key":"2025111811530628600_R136","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/j.1600-0897.1992.tb00767.x","article-title":"Immunosuppression by human seminal plasma&\u2013extracellular organelles (prostasomes) modulate activity of phagocytic cells.","volume":"28","author":"Skibinski","year":"1992","journal-title":"American Journal of Reproductive Immunology"},{"issue":"2","key":"2025111811530628600_R137","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/S0002-9378(97)70215-1","article-title":"Increased incidence of preeclampsia in women conceiving by intrauterine insemination with donor versus partner sperm for treatment of primary infertility.","volume":"177","author":"Smith","year":"1997","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"1","key":"2025111811530628600_R138","doi-asserted-by":"publisher","first-page":"R21","DOI":"10.1530\/REP-13-0058","article-title":"Epididymosomes, prostasomes, and liposomes: their roles in mammalian male reproductive physiology.","volume":"146","author":"Sullivan","year":"2013","journal-title":"Reproduction"},{"issue":"4","key":"2025111811530628600_R139","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1073\/pnas.1118411109","article-title":"Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation.","volume":"109","author":"Sun","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"2025111811530628600_R140","doi-asserted-by":"publisher","DOI":"10.1530\/RAF-23-0088","article-title":"The efficacy and functional consequences of interactions between human spermatozoa and seminal fluid extracellular vesicles.","volume":"5","author":"Tamessar","year":"2024","journal-title":"Reproduction and Fertility"},{"issue":"11","key":"2025111811530628600_R141","doi-asserted-by":"publisher","first-page":"5310","DOI":"10.1210\/endo.140.11.7148","article-title":"Differential uterine expression of estrogen and progesterone receptors correlates with uterine preparation for implantation and decidualization in the mouse.","volume":"140","author":"Tan","year":"1999","journal-title":"Endocrinology"},{"issue":"6","key":"2025111811530628600_R142","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1038\/cmi.2014.42","article-title":"Extracellular vesicles and reproduction-promotion of successful pregnancy.","volume":"11","author":"Tannetta","year":"2014","journal-title":"Cellular & Molecular Immunology"},{"issue":"1-2","key":"2025111811530628600_R143","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.imbio.2010.03.002","article-title":"Human prostasomes express CD48 and interfere with NK cell function.","volume":"216","author":"Tarazona","year":"2011","journal-title":"Immunobiology"},{"issue":"31","key":"2025111811530628600_R144","doi-asserted-by":"publisher","first-page":"11910","DOI":"10.1074\/jbc.RA119.008729","article-title":"The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival.","volume":"294","author":"Tecle","year":"2019","journal-title":"Journal of Biological Chemistry"},{"issue":"1","key":"2025111811530628600_R145","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1530\/jrf.0.0520147","article-title":"Prostaglandin concentrations in the semen of fertile men.","volume":"52","author":"Templeton","year":"1978","journal-title":"Journal of Reproduction and Fertility"},{"issue":"5","key":"2025111811530628600_R146","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1095\/biolreprod58.5.1217","article-title":"Seminal transforming growth factor \u03b21, stimulates granulocyte-macrophage colony-stimulating factor production and inflammatory cell recruitment in the murine uterus.","volume":"58","author":"Tremellen","year":"1998","journal-title":"Biology of Reproduction"},{"issue":"12","key":"2025111811530628600_R147","doi-asserted-by":"publisher","first-page":"2653","DOI":"10.1093\/humrep\/15.12.2653","article-title":"The effect of intercourse on pregnancy rates during assisted human reproduction.","volume":"15","author":"Tremellen","year":"2000","journal-title":"Human Reproduction"},{"issue":"6","key":"2025111811530628600_R148","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1095\/biolreprod.105.044438","article-title":"Uterine artery remodeling in pseudopregnancy is comparable to that in early pregnancy.","volume":"73","author":"van der Heijden","year":"2005","journal-title":"Biology of Reproduction"},{"issue":"7","key":"2025111811530628600_R149","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1038\/nrurol.2016.89","article-title":"The role of the prostate in male fertility, health and disease.","volume":"13","author":"Verze","year":"2016","journal-title":"Nature Reviews Urology"},{"issue":"3","key":"2025111811530628600_R150","doi-asserted-by":"publisher","DOI":"10.1530\/RAF-22-0115","article-title":"A systematic review of transcriptomic studies of the human endometrium reveals inconsistently reported differentially expressed genes.","volume":"4","author":"Walker","year":"2023","journal-title":"Reproduction and Fertility"},{"issue":"9307","key":"2025111811530628600_R151","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/S0140-6736(02)07804-2","article-title":"Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsia.","volume":"359","author":"Wang","year":"2002","journal-title":"The Lancet"},{"issue":"5","key":"2025111811530628600_R152","doi-asserted-by":"publisher","DOI":"10.1210\/endocr\/bqae035","article-title":"Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor.","volume":"165","author":"Wang","year":"2024","journal-title":"Endocrinology"},{"issue":"40","key":"2025111811530628600_R153","doi-asserted-by":"publisher","first-page":"10064","DOI":"10.1073\/pnas.1806333115","article-title":"Paternal diet programs offspring health through sperm- and seminal plasma-specific pathways in mice.","volume":"115","author":"Watkins","year":"2018","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"1","key":"2025111811530628600_R154","doi-asserted-by":"publisher","DOI":"10.1038\/s44294-024-00020-4","article-title":"Endometrial decidualization status modulates endometrial microvascular complexity and trophoblast outgrowth in gelatin methacryloyl hydrogels.","volume":"2","author":"Zambuto","year":"2024","journal-title":"npj Women\u2019s Health"},{"issue":"10","key":"2025111811530628600_R155","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2005-3","article-title":"poFUT1 promotes uterine angiogenesis and vascular remodeling via enhancing the O-fucosylation on uPA.","volume":"10","author":"Zhang","year":"2019","journal-title":"Cell Death & Disease"},{"issue":"7","key":"2025111811530628600_R156","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12457","article-title":"Extracellular vesicles from seminal plasma interact with T cells in vitro and drive their differentiation into regulatory T-cells.","volume":"13","author":"Zhang","year":"2024","journal-title":"Journal of Extracellular Vesicles"}],"container-title":["Reproduction, Fertility and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/doi\/10.1071\/RD24162\/1359616\/rd24162.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/doi\/10.1071\/RD24162\/1359616\/rd24162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T16:53:14Z","timestamp":1763484794000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/rd\/article\/37\/6\/RD24162\/199802\/Seminal-fluid-effects-on-uterine-receptivity-to"}},"subtitle":[],"editor":[{"given":"Jennifer","family":"Juengel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,3,18]]},"references-count":156,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,3,31]]}},"URL":"https:\/\/doi.org\/10.1071\/rd24162","relation":{},"ISSN":["1031-3613","1448-5990"],"issn-type":[{"value":"1031-3613","type":"print"},{"value":"1448-5990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,18]]},"article-number":"RD24162"}}