{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T02:20:59Z","timestamp":1783045259506,"version":"3.54.6"},"reference-count":56,"publisher":"CSIRO Publishing","issue":"10","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,10]]},"abstract":"<jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Tissue fibrosis is described as the excessive accumulation of extracellular matrix (ECM) components. This process is associated with inflammation, and the interaction between fibroblasts and immune cells plays a key role, driving the progression of fibrosis. Results of recent study suggest that interleukin (IL)-12 may play a role in the processes associated with the development of fibrosis. This proinflammatory cytokine is synthesized and released by macrophages, dendritic cells, and B cells.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The objective of this study was to determine: (i) the expression of IL-12 and its receptor in different mare endometrial categories; (ii) the effects of IL-12 on the expression of ECM-related factors; and (iii) endometrial fibroblast functional characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The mRNA expression of IL-12 subunits and IL-12 receptor was determined using quantiative polymerase chain reaction (qPCR). The expression of ECM-related factors and functional characteristics in endometrial fibroblasts were determined using qPCR, Western blotting, zymography with bromodeoxyuridine and scratch assays.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key results<\/jats:title>\n                    <jats:p>IL-12R\u03b22 mRNA expression was upregulated in category IIB endometrium during the mid-luteal phase compared with the follicular phase of the estrous cycle. The IL-12 treatment of endometrial fibroblasts increased mRNA expression of COL1A1, COL3A1, ACTA2, and LOXL2, as well as matrix metalloproteinase (MMP)-9 and MMP3, with elevated pro-MMP2 and MMP9 gelatinolytic activity. Moreover, IL-12 reduced fibroblast proliferation after 96\u00a0h, without effect on migration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings indicate that IL-12 has a direct impact on the mRNA expression of fibrotic markers, MMP-2 and MMP-9 gelatinolytic activity and fibroblast proliferation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications<\/jats:title>\n                    <jats:p>This suggests a potential role for IL-12 in the processes associated with ECM remodeling.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1071\/rd26070","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:57:06Z","timestamp":1783043826000},"source":"Crossref","is-referenced-by-count":0,"title":["Interleukin 12 on extracellular matrix-related factors and functional characteristics of equine endometrial fibroblasts"],"prefix":"10.1071","volume":"38","author":[{"given":"Magda","family":"S\u0142yszewska","sequence":"first","affiliation":[{"name":"ATeam of Molecular Basis of Equine Reproduction, InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-683, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mafalda","family":"Guerreiro","sequence":"additional","affiliation":[{"name":"BC.I.I.S.A., Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Sadowska","sequence":"additional","affiliation":[{"name":"ATeam of Molecular Basis of Equine Reproduction, InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-683, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Jaworska","sequence":"additional","affiliation":[{"name":"ATeam of Molecular Basis of Equine Reproduction, InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-683, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gra\u00e7a","family":"Ferreira-Dias","sequence":"additional","affiliation":[{"name":"BC.I.I.S.A., Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal."},{"name":"CAssociate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Lisbon, Portugal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4204-1698","authenticated-orcid":true,"given":"Anna","family":"Sz\u00f3stek-Mioduchowska","sequence":"additional","affiliation":[{"name":"ATeam of Molecular Basis of Equine Reproduction, InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-683, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"67","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"issue":"13","key":"2026070221570071600_R1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11132028","article-title":"The role of the immune system in the development of endometriosis.","volume":"11","author":"Abramiuk","year":"2022","journal-title":"Cells"},{"issue":"1","key":"2026070221570071600_R2","doi-asserted-by":"publisher","DOI":"10.15252\/msb.20156423","article-title":"Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress.","volume":"12","author":"Cheng","year":"2016","journal-title":"Molecular Systems Biology"},{"issue":"5","key":"2026070221570071600_R3","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/j.fertnstert.2019.02.005","article-title":"Inflammation and uterine fibrosis: the possible role of chronic endometritis.","volume":"111","author":"de Ziegler","year":"2019","journal-title":"Fertility and Sterility"},{"key":"2026070221570071600_R4"},{"issue":"4","key":"2026070221570071600_R5","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/S0945-053X(00)00077-9","article-title":"Fibroblast-matrix interactions in wound healing and fibrosis.","volume":"19","author":"Eckes","year":"2000","journal-title":"Matrix Biology"},{"key":"2026070221570071600_R6","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2025.107873","article-title":"Substrate stiffness modifies gene expression and transcriptional response of equine endometrial fibroblasts to TGF-\u03b21.","volume":"278","author":"Elena","year":"2025","journal-title":"Animal Reproduction Science"},{"issue":"2","key":"2026070221570071600_R7","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13145","article-title":"Alteration of the mare\u2019s immune system by the synthetic progestin, altrenogest.","volume":"82","author":"Fedorka","year":"2019","journal-title":"American Journal of Reproductive Immunology"},{"issue":"2","key":"2026070221570071600_R8","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1111\/j.1439-0531.1995.tb00606.x","article-title":"Endometrosis in mares: incidence of histopathological alterations.","volume":"30","author":"Flores","year":"1995","journal-title":"Reproduction in Domestic Animals"},{"issue":"7","key":"2026070221570071600_R9","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1071\/RD12153","article-title":"Effect of cytokines and ovarian steroids on equine endometrial function: an in vitro study.","volume":"25","author":"Galv\u00e3o","year":"2013","journal-title":"Reproduction, Fertility and Development"},{"key":"2026070221570071600_R10","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1146\/annurev.immunol.16.1.495","article-title":"The interleukin-12\/interleukin-12-receptor system: role in normal and pathologic immune responses.","volume":"16","author":"Gately","year":"1998","journal-title":"Annual Review of Immunology"},{"issue":"1","key":"2026070221570071600_R11","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/0008-8749(92)90011-D","article-title":"Regulation of human cytolytic lymphocyte responses by interleukin-12.","volume":"143","author":"Gately","year":"1992","journal-title":"Cellular Immunology"},{"issue":"2","key":"2026070221570071600_R12","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1242\/dmm.012062","article-title":"Diverse functions of matrix metalloproteinases during fibrosis.","volume":"7","author":"Giannandrea","year":"2014","journal-title":"Disease Models & Mechanisms"},{"issue":"3","key":"2026070221570071600_R13","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1111\/jre.12398","article-title":"Doxycycline reduces the expression and activity of matrix metalloproteinase-2 in the periodontal ligament of the rat incisor without altering the eruption process.","volume":"52","author":"Gomes","year":"2017","journal-title":"Journal of Periodontal Research"},{"issue":"3","key":"2026070221570071600_R14","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.cell.2025.12.014","article-title":"Fibroblasts of disparate developmental origins harbor anatomically variant scarring potential.","volume":"189","author":"Griffin","year":"2026","journal-title":"Cell"},{"issue":"9","key":"2026070221570071600_R15","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1093\/ibd\/izy142","article-title":"Reversing Ongoing chronic intestinal inflammation and fibrosis by sustained block of IL-12 and IL-23 using a vaccine in mice.","volume":"24","author":"Guan","year":"2018","journal-title":"Inflammatory Bowel Diseases"},{"issue":"2","key":"2026070221570071600_R16","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1294\/jes.25.45","article-title":"Histopathological characteristics of endometrosis in thoroughbred mares in Japan: results from 50 necropsy cases.","volume":"25","author":"Hanada","year":"2014","journal-title":"Journal of Equine Science"},{"issue":"2","key":"2026070221570071600_R17","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.anireprosci.2008.03.019","article-title":"The equine endometrosis: New insights into the pathogenesis.","volume":"111","author":"Hoffmann","year":"2009","journal-title":"Animal Reproduction Science"},{"issue":"10","key":"2026070221570071600_R18","doi-asserted-by":"publisher","DOI":"10.3390\/s18103249","article-title":"Matrix Metalloproteinase-9 (MMP-9) as a cancer biomarker and MMP-9 biosensors: recent advances.","volume":"18","author":"Huang","year":"2018","journal-title":"Sensors"},{"issue":"5","key":"2026070221570071600_R19","doi-asserted-by":"publisher","first-page":"2653","DOI":"10.4049\/jimmunol.169.5.2653","article-title":"A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.","volume":"169","author":"Huaux","year":"2002","journal-title":"The Journal of Immunology"},{"issue":"6","key":"2026070221570071600_R20","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1002\/wrna.1244","article-title":"Interrelations between translation and general mRNA degradation in yeast.","volume":"5","author":"Huch","year":"2014","journal-title":"Wiley Interdisciplinary Reviews: RNA"},{"issue":"1","key":"2026070221570071600_R21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74179-6","article-title":"Dermal fibroblasts have different extracellular matrix profiles induced by TGF-\u03b2, PDGF and IL-6 in a model for skin fibrosis.","volume":"10","author":"Juhl","year":"2020","journal-title":"Scientific Reports"},{"issue":"1","key":"2026070221570071600_R22","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1172\/JCI93563","article-title":"Resolution of organ fibrosis.","volume":"128","author":"Jun","year":"2018","journal-title":"The Journal of Clinical Investigation"},{"issue":"6","key":"2026070221570071600_R23","doi-asserted-by":"publisher","DOI":"10.3390\/ani12060779","article-title":"Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares.","volume":"12","author":"Katila","year":"2022","journal-title":"Animals"},{"issue":"1","key":"2026070221570071600_R24","doi-asserted-by":"publisher","first-page":"L92","DOI":"10.1152\/ajplung.2001.281.1.L92","article-title":"IL-12 attenuates bleomycin-induced pulmonary fibrosis.","volume":"281","author":"Keane","year":"2001","journal-title":"American Journal of Physiology-Lung Cellular and Molecular Physiology"},{"issue":"3","key":"2026070221570071600_R25","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2460\/javma.1978.172.03.241","article-title":"Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on early embryonic death.","volume":"172","author":"Kenney","year":"1978","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"2026070221570071600_R26"},{"issue":"3","key":"2026070221570071600_R27","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1084\/jem.170.3.827","article-title":"Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.","volume":"170","author":"Kobayashi","year":"1989","journal-title":"The Journal of Experimental Medicine"},{"issue":"5","key":"2026070221570071600_R28","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/j.fertnstert.2019.01.006","article-title":"The impact of chronic endometritis on endometrial fibrosis and reproductive prognosis in patients with moderate and severe intrauterine adhesions: a prospective cohort study.","volume":"111","author":"Liu","year":"2019","journal-title":"Fertility and Sterility"},{"issue":"1","key":"2026070221570071600_R29","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-36416-6","article-title":"Fibroblasts are not just fibroblasts: clear differences between dermal and pulmonary fibroblasts\u2019 response to fibrotic growth factors.","volume":"13","author":"Madsen","year":"2023","journal-title":"Scientific Reports"},{"key":"2026070221570071600_R30","doi-asserted-by":"publisher","first-page":"453","DOI":"10.2741\/2692","article-title":"Macrophage activation and polarization.","volume":"13","author":"Martinez","year":"2008","journal-title":"Frontiers in Bioscience"},{"key":"2026070221570071600_R31","unstructured":"Masseno APB (2012) Avalia\u00e7\u00e3o da fibrose endometrial e dos miofibroblastos nas endometroses ativa e inativa da \u00e9guas. pp. 110. Doctoral Thesis. Faculdade de Medicina Veterin\u00e1ria e Zootecnia, Universidade Estadual Paulista, Botucatu. [In Portuguese with English abstract]"},{"issue":"6","key":"2026070221570071600_R32","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20170973","article-title":"Interleukin-12-mediated expression of matrix metalloproteinases in human periodontal ligament fibroblasts involves NF-\u03baB activation.","volume":"37","author":"Miao","year":"2017","journal-title":"Bioscience Reports"},{"issue":"1","key":"2026070221570071600_R33","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1093\/biolre\/ioaf217","article-title":"Proteomic profiling of endometrial tissue and plasma from mares with endometrial fibrosis.","volume":"114","author":"Muderspach","year":"2026","journal-title":"Biology of Reproduction"},{"issue":"3","key":"2026070221570071600_R34","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.cardiores.2005.12.002","article-title":"Structure and function of matrix metalloproteinases and TIMPs.","volume":"69","author":"Nagase","year":"2006","journal-title":"Cardiovascular Research"},{"issue":"1","key":"2026070221570071600_R35","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2025.114584","article-title":"Antifibrotic effects of IL-12-treated natural killer cells on collagen type I regulation in lung fibroblasts.","volume":"449","author":"Okuno","year":"2025","journal-title":"Experimental Cell Research"},{"issue":"6","key":"2026070221570071600_R36","doi-asserted-by":"publisher","first-page":"2116","DOI":"10.1046\/j.1523-1755.1999.00775.x","article-title":"Interferon-gamma inhibits experimental renal fibrosis.","volume":"56","author":"Oldroyd","year":"1999","journal-title":"Kidney International"},{"issue":"9401","key":"2026070221570071600_R37","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1016\/S0140-6736(03)15109-4","article-title":"Viral hepatitis C.","volume":"362","author":"Poynard","year":"2003","journal-title":"The Lancet"},{"issue":"24","key":"2026070221570071600_R38","doi-asserted-by":"publisher","first-page":"14002","DOI":"10.1073\/pnas.93.24.14002","article-title":"A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.","volume":"93","author":"Presky","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"8","key":"2026070221570071600_R39","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.matbio.2007.07.001","article-title":"Control of matrix metalloproteinase catalytic activity.","volume":"26","author":"Ra","year":"2007","journal-title":"Matrix Biology"},{"issue":"1","key":"2026070221570071600_R40","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a004978","article-title":"The collagen family.","volume":"3","author":"Ricard-Blum","year":"2011","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"issue":"3","key":"2026070221570071600_R41","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20171420","article-title":"IL-12-mediated transcriptional regulation of matrix metalloproteinases.","volume":"38","author":"Roupakia","year":"2018","journal-title":"Bioscience Reports"},{"issue":"23","key":"2026070221570071600_R42","doi-asserted-by":"publisher","DOI":"10.3390\/ijms262311344","article-title":"Transcriptomic insights into tumor necrosis factor \u03b1\u2019s role in the fibrosis-related processes of equine endometrial fibroblasts.","volume":"26","author":"Sadowska","year":"2025","journal-title":"International Journal of Molecular Sciences"},{"key":"2026070221570071600_R43","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2025.117680","article-title":"Interleukin 17A in the fibrotic-related processes in endometrosis in the mare.","volume":"249","author":"Sadowska","year":"2026","journal-title":"Theriogenology"},{"key":"2026070221570071600_R49","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/208103","article-title":"Interleukins affect equine endometrial cell function: modulatory action of ovarian steroids.","volume":"2014","author":"Sz\u00f3stek","year":"2014","journal-title":"Mediators of Inflammation"},{"key":"2026070221570071600_R44","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2019.154767","article-title":"Effect of proinflammatory cytokines on endometrial collagen and metallopeptidase expression during the course of equine endometrosis.","volume":"123","author":"Sz\u00f3stek-Mioduchowska","year":"2019","journal-title":"Cytokine"},{"key":"2026070221570071600_R45","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.theriogenology.2018.10.005","article-title":"Effect of transforming growth factor-\u03b21 on \u03b1-smooth muscle actin and collagen expression in equine endometrial fibroblasts.","volume":"124","author":"Sz\u00f3stek-Mioduchowska","year":"2019","journal-title":"Theriogenology"},{"issue":"1","key":"2026070221570071600_R46","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58109-0","article-title":"Matrix metallopeptidase expression and modulation by transforming growth factor-\u03b21 in equine endometrosis.","volume":"10","author":"Sz\u00f3stek-Mioduchowska","year":"2020","journal-title":"Scientific Reports"},{"issue":"1","key":"2026070221570071600_R47","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-43359-5","article-title":"Transcriptomic profiling of mare endometrium at different stages of endometrosis.","volume":"13","author":"Sz\u00f3stek-Mioduchowska","year":"2023","journal-title":"Scientific Reports"},{"issue":"4","key":"2026070221570071600_R50","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1002\/jlb.59.4.505","article-title":"Immunoregulation by interleukin-12.","volume":"59","author":"Trinchieri","year":"1996","journal-title":"Journal of Leukocyte Biology"},{"issue":"8","key":"2026070221570071600_R51","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1038\/ni.2366","article-title":"IL-12 family cytokines: immunological playmakers.","volume":"13","author":"Vignali","year":"2012","journal-title":"Nature Immunology"},{"issue":"5","key":"2026070221570071600_R52","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S1359-6101(03)00043-1","article-title":"The biology of IL-12: coordinating innate and adaptive immune responses.","volume":"14","author":"Watford","year":"2003","journal-title":"Cytokine & Growth Factor Reviews"},{"key":"2026070221570071600_R53","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2023.1271240","article-title":"Mare stromal endometrial cells differentially modulate inflammation depending on oestrus cycle status: an in vitro study.","volume":"10","author":"Wong","year":"2023","journal-title":"Frontiers in Veterinary Science"},{"issue":"2","key":"2026070221570071600_R54","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-026-04049-6","article-title":"Interleukin-4 changes the transcriptome, ECM-associated components and function of mare endometrial fibroblast: Insights from healthy and fibrotic cells.","volume":"403","author":"W\u00f3jtowicz","year":"2026","journal-title":"Cell and Tissue Research"},{"issue":"7","key":"2026070221570071600_R55","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.107201","article-title":"Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH.","volume":"26","author":"Yao","year":"2023","journal-title":"iScience"},{"issue":"2","key":"2026070221570071600_R56","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1101\/gad.14.2.163","article-title":"Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.","volume":"14","author":"Yu","year":"2000","journal-title":"Genes & Development"},{"issue":"8","key":"2026070221570071600_R57","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1089\/cmb.2005.12.1047","article-title":"Comprehensive algorithm for quantitative real-time polymerase chain reaction.","volume":"12","author":"Zhao","year":"2005","journal-title":"Journal of Computational Biology"}],"container-title":["Reproduction, Fertility and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/doi\/10.1071\/RD26070\/1943750\/rd26070.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/rd\/article-pdf\/doi\/10.1071\/RD26070\/1943750\/rd26070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:57:12Z","timestamp":1783043832000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/rd\/article\/38\/10\/RD26070\/273177\/Interleukin-12-on-extracellular-matrix-related"}},"subtitle":[],"editor":[{"given":"Greg","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,7,3]]},"references-count":56,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,7,10]]}},"URL":"https:\/\/doi.org\/10.1071\/rd26070","relation":{},"ISSN":["1031-3613","1448-5990"],"issn-type":[{"value":"1031-3613","type":"print"},{"value":"1448-5990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,3]]},"article-number":"RD26070"}}