{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T23:12:46Z","timestamp":1761347566408,"version":"build-2065373602"},"reference-count":15,"publisher":"CSIRO Publishing","issue":"4","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":2562,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,7,27]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data regarding sexually transmissible infections (STI) often originate from STI clinics, screening programs or laboratory-based studies, thus are biased for specific risk groups or lack clinical details. This real-life observational study presents sample data of most young adult Israeli population by exploiting the centralised diagnostic and documentation platforms resulting from a mandatory military service at the age of 18 years for both genders. Methods: All STI diagnoses of Israeli Defence Forces soldiers during a 6-month period were reviewed. Patients with Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) (major-STI) and Ureaplasma urealyticum (UU), Ureaplasma parvum (UP) and Mycoplasma hominis (MH) (equivocal STI) were compared with STI-negative controls. Results: Sexually transmissible infection positivity rates (n = 2816) were as follows: CT 6.6%; MG 1.9%; NG 0.7%; TV 0.5%; UU 15.7%; UP 28.2%; and MH 6.2%. The CT+MG coinfection rate was 4.1%, yet CT+NG coinfections were rare (\u02dc0.5%). More than half of the patients with ureaplasmas and\/or MH were treated; 40% of them were recommended partner treatment. Most antibiotics were prescribed to patients with equivocal infections. Classic STI symptoms in males were linked to major-STI and UU, while females were asymptomatic or presented non-specific symptoms. Conclusions: The judicious use of antibiotics in the era of antimicrobial resistance necessitates re-evaluating the significance of equivocal pathogen detection and reporting (MH, UU, UP). Likewise, universal empiric treatment for NG should be reconsidered in light of its low rates in non-high-risk groups. Conversely, a high MG rate, a pathogen with potential resistance to common STI protocols, requires evaluation of guidelines adequacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1071\/sh17190","type":"journal-article","created":{"date-parts":[[2018,4,29]],"date-time":"2018-04-29T21:20:35Z","timestamp":1525036835000},"page":"298-303","source":"Crossref","is-referenced-by-count":7,"title":["Management of sexually transmissible infections in the era of multiplexed molecular diagnostics: a primary care survey"],"prefix":"10.1071","volume":"15","author":[{"given":"Tal","family":"Brosh-Nissimov","sequence":"first","affiliation":[{"name":"AThe Infectious Disease Unit, Assuta Ashdod University Hospital, Harefua 7, Ashdod 7747629, Israel."},{"name":"BIsrael Defense Forces Medical Corps, Tel Hashomer, MilPOB 02149, Israel."},{"name":"ECorresponding author. Email: tbrosh@gmail.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Kedem","sequence":"additional","affiliation":[{"name":"BIsrael Defense Forces Medical Corps, Tel Hashomer, MilPOB 02149, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimrod","family":"Ophir","sequence":"additional","affiliation":[{"name":"BIsrael Defense Forces Medical Corps, Tel Hashomer, MilPOB 02149, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omri","family":"Shental","sequence":"additional","affiliation":[{"name":"BIsrael Defense Forces Medical Corps, Tel Hashomer, MilPOB 02149, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Keller","sequence":"additional","affiliation":[{"name":"CThe Department of Clinical Microbiology, Sheba Medical Center, Emek Haela 1, Ramat-Gan 5265601, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Amit","sequence":"additional","affiliation":[{"name":"CThe Department of Clinical Microbiology, Sheba Medical Center, Emek Haela 1, Ramat-Gan 5265601, Israel."},{"name":"DThe Department of Clinical Microbiology and Infectious Diseases, Hadassah University Hospital, Jerusalem 91120, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"67","published-online":{"date-parts":[[2018,4,30]]},"reference":[{"key":"2025102419073813000_R1","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.3201\/eid0910.030100","article-title":"Chlamydia trachomatis infections in female soldiers, Israel.","volume":"9","author":"Bamberger","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"2025102419073813000_R2","first-page":"152","article-title":"Syphilis outbreak among men who have sex with men, Tel Aviv, Israel 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Israel?","volume":"23","author":"Chemtob","year":"2012","journal-title":"Int J STD AIDS"},{"key":"2025102419073813000_R6","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1097\/OLQ.0b013e318286dba6","article-title":"Estimates of sexually transmitted infection prevalence and incidence in the United States: time to embrace uncertainty.","volume":"40","author":"Miller","year":"2013","journal-title":"Sex Transm Dis"},{"key":"2025102419073813000_R7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00008480-200308000-00006","article-title":"Sexually transmitted diseases treatment guidelines.","volume":"64","author":"Workowski","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"2025102419073813000_R8","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1177\/0956462412472837","article-title":"2012 European guideline on the diagnosis and treatment of gonorrhoea in adults.","volume":"24","author":"Bignell","year":"2013","journal-title":"Int J STD 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Rep"},{"key":"2025102419073813000_R13","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1093\/infdis\/jir517","article-title":"Ureaplasma urealyticum is associated with nongonococcal urethritis among men with fewer lifetime sexual partners: a case-control study.","volume":"204","author":"Wetmore","year":"2011","journal-title":"J Infect Dis"},{"key":"2025102419073813000_R14","doi-asserted-by":"publisher","first-page":"e113771","DOI":"10.1371\/journal.pone.0113771","article-title":"Are Ureaplasma spp. a cause of nongonococcal urethritis? A systematic review and meta-analysis.","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS One"},{"key":"2025102419073813000_R15","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1177\/0956462413515196","article-title":"Mycoplasma genitalium: a review.","volume":"25","author":"Daley","year":"2014","journal-title":"Int J STD AIDS"}],"container-title":["Sexual Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/sh\/article-pdf\/15\/4\/298\/147119\/sh17190.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/sh\/article-pdf\/15\/4\/298\/147119\/sh17190.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T23:07:43Z","timestamp":1761347263000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/sh\/article\/15\/4\/298\/21323\/Management-of-sexually-transmissible-infections-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,30]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7,27]]}},"URL":"https:\/\/doi.org\/10.1071\/sh17190","relation":{},"ISSN":["1448-5028","1449-8987"],"issn-type":[{"type":"print","value":"1448-5028"},{"type":"electronic","value":"1449-8987"}],"subject":[],"published":{"date-parts":[[2018,4,30]]}}}