{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T08:49:49Z","timestamp":1765788589021,"version":"3.48.0"},"reference-count":23,"publisher":"CSIRO Publishing","issue":"9","license":[{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"vor","delay-in-days":6195,"URL":"https:\/\/doi.org\/10.1071\/journalslicense"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,9,5]]},"abstract":"<jats:p>Novel 3-alkyl-3',4',5,7-tetrahydroxyflavones have been prepared. The synthetic strategy involves the preparation of 1-(2-hydroxy-4,6-dimethoxyphenyl)alkan-1-ones from the Friedel\u2013Crafts acylation of phloroglucinol followed by methylation. These key compounds were submitted to the three-step Baker\u2013Venkataraman method, giving the 3-alkyl-3',4',5,7-tetramethoxyflavones, which were demethylated with boron tribromide.<\/jats:p>","DOI":"10.1071\/ch08162","type":"journal-article","created":{"date-parts":[[2009,2,8]],"date-time":"2009-02-08T21:40:19Z","timestamp":1234129219000},"page":"718-724","source":"Crossref","is-referenced-by-count":14,"title":["Synthesis of Novel 3-Alkyl-3',4',5,7-Tetrahydroxyflavones"],"prefix":"10.1071","volume":"61","author":[{"given":"Raquel S. G. R.","family":"Seixas","sequence":"first","affiliation":[{"name":"ADepartment of Chemistry & QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal."}]},{"given":"Diana C. G. A.","family":"Pinto","sequence":"additional","affiliation":[{"name":"ADepartment of Chemistry & QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal."}]},{"given":"Artur M. S.","family":"Silva","sequence":"additional","affiliation":[{"name":"ADepartment of Chemistry & QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal."},{"name":"BCorresponding author. Email: artur.silva@ua.pt"}]},{"given":"Jos\u00e9 A. S.","family":"Cavaleiro","sequence":"additional","affiliation":[{"name":"ADepartment of Chemistry & QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal."}]}],"member":"67","published-online":{"date-parts":[[2008,9,5]]},"reference":[{"key":"2025121503465343700_R1"},{"key":"2025121503465343700_R2"},{"key":"2025121503465343700_R3"},{"key":"2025121503465343700_R4"},{"key":"2025121503465343700_R5"},{"key":"2025121503465343700_R6"},{"key":"2025121503465343700_R7"},{"key":"2025121503465343700_R8"},{"key":"2025121503465343700_R9"},{"key":"2025121503465343700_R10"},{"key":"2025121503465343700_R11"},{"key":"2025121503465343700_R12"},{"key":"2025121503465343700_R13"},{"key":"2025121503465343700_R14"},{"key":"2025121503465343700_R15"},{"key":"2025121503465343700_R16"},{"key":"2025121503465343700_R17"},{"key":"2025121503465343700_R18"},{"key":"2025121503465343700_R19"},{"key":"2025121503465343700_R20"},{"key":"2025121503465343700_R21"},{"key":"2025121503465343700_R22"},{"key":"2025121503465343700_R23"}],"container-title":["Australian Journal of Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/connectsci.au\/ch\/article-pdf\/61\/9\/718\/1012534\/ch08162.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/connectsci.au\/ch\/article-pdf\/61\/9\/718\/1012534\/ch08162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T08:46:56Z","timestamp":1765788416000},"score":1,"resource":{"primary":{"URL":"https:\/\/connectsci.au\/ch\/article\/61\/9\/718\/126769\/Synthesis-of-Novel-3-Alkyl-3-4-5-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,5]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2008,9,5]]}},"URL":"https:\/\/doi.org\/10.1071\/ch08162","relation":{},"ISSN":["0004-9425","1445-0038"],"issn-type":[{"type":"print","value":"0004-9425"},{"type":"electronic","value":"1445-0038"}],"subject":[],"published":{"date-parts":[[2008,9,5]]}}}